Skip to main content
Medically Approved

High blood sugar: When is it a medical emergency?

twitter share buttonfacebook share buttonlinkedin share buttonemail article button
Optimal to dangerous blood sugarSymptomsCausesHigh blood sugar without diabetesCan you lower it quickly?How to lower blood sugarSummary
Rapid breathing, abdominal pain, severe thirst, mental confusion, and loss of consciousness may signal extremely high blood sugar levels. Readings above 250 mg/dL also signal the need for immediate medical assistance.
Medically reviewed by Lauren Castiello, MS, AGNP-C
Written by Rashida Ruwa, RN
Updated on

Hyperglycemia is the medical term for high blood sugar. This refers to blood glucose levels above the optimal range. Still, a wide range of possibilities go from slightly higher to significantly higher.

In some cases, extremely high blood sugar becomes a medical emergency

Blood sugar levels are measured using milligrams per deciliter (mg/dL) or millimoles per liter (mmol/L). Doctors often use a blood glucose meter to analyze a small blood sample, typically taken from a finger prick, and determine the glucose concentration in the blood.

Treatment is available and effective for high blood sugar. Timing is key for critical high blood sugar, and emergency medical care is lifesaving.

Blood sugar levels: What is ‘too high’?

Man checking his blood sugar to see if it's dangerously high
EXTREME-PHOTOGRAPHER/Getty Images

Your blood sugar levels are significantly high if you get a reading above 126 mg/dL. Anything above 180 mg/dL needs prompt medical care. Any reading above 250 mg/dL is a critical medical emergency.

A medical emergency means your blood sugar levels may jeopardize your health and life, and you need immediate medical intervention to lower those safely. Going to the emergency room is highly advised.

Blood sugar ranges

For a healthy adult, the standard range for fasting blood sugar levels (measured after an overnight fast) is generally 70–100 mg/dL

However, if you have diabetes, target ranges for blood sugar levels may differ depending on the type of diabetes, age, overall health, and other individual factors. Your healthcare professional may provide you with blood sugar ranges for your case.

According to the World Health Organization (WHO), the expected values for fasting blood glucose in adults are:

  • Normal range: 70–100 mg/dL
  • Low blood sugar (hypoglycemia): below 70 mg/dL
  • High blood sugar (hyperglycemia): 100–125 mg/dL
  • Critical high levels: above 250 mg/dL

There are generally no significant differences in blood sugar ranges between males and females, although hormonal fluctuations during the menstrual cycle may temporarily affect blood sugar levels. 

Factors like high carbohydrate foods, stress, and dehydration may also temporarily raise blood sugar levels in both males and females, although individual responses may differ.

Symptoms of high blood sugar

Symptoms of high blood sugar may vary depending on how high they are and for how long. Typically, they may include:

  • urinating often
  • feeling more thirsty
  • unexplained fatigue
  • blurred vision
  • sudden and persistent headaches

Symptoms of very high blood sugar levels, indicating a medical emergency, may include:

  • extreme thirst that does not go away by drinking fluids
  • rapid breathing
  • heart palpitations
  • abdominal pain
  • mental confusion or disorientation
  • fruity scented breath
  • numbness in one or more limbs
  • loss of consciousness

Immediate medical assistance is needed for these severe symptoms.

Causes of high blood sugar

Possible causes of persistent high blood sugar may include:

  • poor insulin production or insulin resistance
  • insufficient insulin dosage if you live with diabetes
  • untreated or undiagnosed diabetes
  • medication side effects, such as from corticosteroids 
  • health conditions like hormonal imbalances or pancreatic disorders
  • chronic stress

Persistent high blood sugar may lead to health complications if left untreated. Common complications may include:

  • diabetic ketoacidosis (DKA)
  • cardiovascular diseases
  • nerve damage
  • kidney failure
  • hyperglycemic hyperosmolar state (HSS)

Can a person without diabetes have high blood sugar levels?

A person without diabetes can have high blood sugar levels.

Causes of high blood sugar without a diagnosis of diabetes may include:

  • release of hormones due to high levels of psychological stress
  • side effects from certain medications, such as corticosteroids
  • pancreatic disorders such as pancreatitis
  • menstrual periods, which cause hormonal imbalances 
  • dehydration

How quickly can you lower blood sugar levels?

Lowering blood sugar levels quickly may depend on factors like:

  • how high your blood sugar is
  • whether you live with diabetes or other conditions
  • your blood sugar intervention method (insulin shot or oral medication)
  • whether the insulin is fast-acting or slow release
  • the cause and duration of your blood sugar spike
  • how active you are, as exercise tends to lower blood sugar levels quickly
  • your natural body’s response

Generally, a noticeable decrease in your blood sugar levels may take minutes to hours, depending on the above factors and medical intervention.

Medical intervention can lower your levels quickly and safely for significantly high blood sugar.

If you need help covering the cost of medications, the free Optum Perks Discount Card could help you save up to 80% on prescription drugs. Follow the links on drug names for savings on that medication, or search for a specific drug here.

Pill bottle with text 'Starts at $4'

Free prescription coupons

Seriously … free. Explore prices that beat the competition 70% of the time.

Get free card

How to lower blood sugar levels

During a medical emergency, a healthcare professional may lower your blood sugar levels safely by giving insulin through a vein (intravenous insulin therapy) and replacing fluid and electrolytes via IV.

You can lower your blood sugar levels through medical intervention and lifestyle modifications.

Lifestyle habits like at least 150 minutes of physical activity per week, a nutrient-dense diet, and stress management may help reverse and keep your blood sugar at an optimal level.

Your healthcare professional may prescribe medications if you live with persistently high blood sugar. Following instructions is critical in lowering high blood sugar.

Common medications used to help lower high blood sugars may include:

Insulin 

Various forms of insulin delivery are available, including rapid-acting, short-acting, intermediate-acting, and long-acting insulin shots.

Some available forms of insulin include:

A doctor may prescribe insulin when other treatment methods, such as oral medications or lifestyle changes, won’t affect your blood sugar levels effectively.

Insulin is a hormone and medication classified as an antidiabetic agent. It helps lower blood sugar levels by promoting the uptake and utilization of glucose by cells. 

Common side effects of insulin may include:

  • hypoglycemia
  • weight gain
  • injection site reactions

The benefits of insulin often outweigh these potential side effects.

Metformin

Metformin (Riomet) is an oral medication belonging to the biguanide class. It lowers blood sugar by reducing glucose production in the liver and enhancing muscle glucose uptake. 

Common side effects may include: 

  • nausea
  • vomiting
  • diarrhea

Need a refill for metformin (Glucophage)? You may be able to get an online prescription through Optum Perks in as little as 15 minutes with no video or appointment needed. Learn more here.

Man on phone in bed

100% online care

Treatment plans in 15 minutes or less for 40+ conditions.

Start consult now

Glipizide

Glipizide (Glucotrol) is an oral medication classified as a sulfonylurea. It stimulates insulin from the pancreas, helping to lower blood sugar levels.  

Common side effects may include:

  • hypoglycemia
  • weight gain
  • nausea

Sitagliptin

Sitagliptin (Januvia) is an oral medication classified as a dipeptidyl peptidase-4 (DPP-4) inhibitor. It helps increase the incretin hormone. This hormone stimulates insulin release and reduces glucagon secretion, which helps lower blood sugar levels.

Common side effects may include:

  • upper respiratory tract infections
  • headaches

Summary

Extremely high blood sugar — above 250 mg/dL — may lead to severe health challenges and is considered a medical emergency.

Persistent high blood sugar, even if slightly over the optimal range, may indicate the need for medical intervention. Checking for symptoms like constant thirst, urinating more often, and unexplained fatigue may signal higher than optimal blood sugar levels. Consulting with a healthcare professional is highly advised.

Lifestyle changes, and in some cases medications, can help you lower high blood sugar and keep it at optimal levels.

Download the free Optum Perks Discount Card to save up to 80% on some prescription medications.

Article resources