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Medically Approved

Metolazone oral tablet dosage: A detailed guide

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Doctors prescribe metolazone oral tablet for high blood pressure and fluid retention due to kidney disease or heart failure. You take it by mouth once per day.
Medically reviewed by Amber R. Watson, PharmD
Updated on

This article describes metolazone oral tablet’s dosages and strengths and gives details on how to take it. You’ll also find information on cost savings and coupon options for metolazone. If you want to know more about metolazone oral tablet, see this overview article. It covers details about the drug’s uses and side effects, ways to save on cost, and more.

Metolazone oral tablet is a generic medication. It’s not available in a brand-name version. Metolazone only comes in oral tablet form.

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Form and strengths of metolazone

Metolazone oral tablet comes as follows:

  • Form: tablet that you swallow
  • Strengths: 2.5 milligrams (mg), 5 mg, and 10 mg

Dosage of metolazone

This article describes the recommended dosages for metolazone oral tablet. The drugmaker provides these dosages.

If your doctor prescribes this medication, you should follow the dosage they prescribe. Your doctor will determine the dosage that best meets your needs. Do not change your dosage of metolazone oral tablet without your doctor’s recommendation.

Usual recommended dosages of metolazone in adults

Usually, doctors start by prescribing a low dosage of metolazone oral tablet. Then, they’ll adjust it over time until the right dosage is reached. Ultimately, your doctor will prescribe the smallest dosage of metolazone oral tablet that gives the desired outcome.

The dosage for fluid retention caused by kidney disease or heart failure is:

  • Starting dosage: 5 mg once per day
  • Maximum dosage: 20 mg once per day

The dosage for high blood pressure is:

  • Starting dosage: 2.5 mg once per day
  • Maximum dosage: 5 mg once per day

Dosages of metolazone in children

The safety and effectiveness of metolazone has not been established in children. But your doctor may determine that your child may benefit from metolazone oral tablet.

Usual doses are based on your child’s weight in kilograms (kg). Doses generally range from 0.05 mg to 0.1 mg per kg of body weight and are taken once per day. For example, if your child weighs 100 pounds (lb), which is about 50 kg, their dose will range from 2.5–5 mg taken once per day.

Dosage adjustments for metolazone

Your doctor will prescribe a dosage of metolazone oral tablet based on several factors. These include:

  • the specific condition being treated and how severe it is
  • your age
  • other health conditions you may have

Missed dose of metolazone

Talk with your doctor or pharmacist right away if you realize you forgot to take a dose of metolazone oral tablet. They may advise you to take the missed dose. Or they may advise you to skip it and take your next dose as scheduled.

For tips on how to plan your doses of metolazone oral tablet and avoid missing a dose, read this article. You could also try:

  • downloading a reminder app on your phone
  • setting an alarm
  • putting a note where you’ll see it, such as on your calendar, bathroom mirror, or bedside table

Frequently asked questions

Below are answers to some commonly asked questions about metolazone oral tablet and its dosage.

Can I take metolazone and Lasix together? If so, what is the dosage?

Metolazone and Lasix should only be taken together if your doctor prescribes both of them for you. Either drug may be prescribed for high blood pressure and fluid retention due to kidney disease or heart failure. Your doctor will likely want to see how your symptoms are managed at the maximum dosage of either drug alone before adding the other.

Taking metolazone and Lasix together may have a greater effect on your condition than taking the maximum dosage of either drug alone. Specifically, taking them together may result in greater decreases in blood pressure and fluid levels. So close monitoring is needed when both are taken together.

Dosing can vary depending on the severity of your condition and how well your body responds to the drugs. Your doctor will likely start with a low dose and slowly increase it over time.

Talk with your doctor if you want to learn more about taking metolazone and Lasix together.

Is metolazone taken long term?

Yes, doctors typically prescribe metolazone oral tablet as a long-term treatment. If you and your doctor determine that it’s safe and effective for your condition, you’ll likely take it long term.

If you have questions about how long you should take metolazone oral tablet, talk with your doctor.

How metolazone is taken

You’ll swallow metolazone oral tablet once per day.

Your doctor may advise that you take this medication around the same time each day. This helps keep a consistent amount of the drug in your body. And that can help the drug work more effectively.

If it’s hard for you to swallow tablets, view this article. It provides suggestions on how to swallow medications that come in pill form.

Also, be sure to talk with your doctor or pharmacist if you’re having difficulty taking your medication. They can offer recommendations about taking it.

Metolazone coupon

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Overdose of metolazone

It’s important that you do not take more metolazone oral tablet than your doctor prescribes. Doing so can lead to harmful effects.

Symptoms of metolazone overdose

Symptoms of an overdose can include:

  • dizziness or lightheadedness
  • drowsiness or lethargy
  • fainting
  • decreased breathing

What to do if you take too much metolazone

If you think you’ve taken too much metolazone, call your doctor or pharmacist right away. Or you could call 800-222-1222 to speak with someone at America’s Poison Centers. You can also use its online resource. If you have severe symptoms, call 911 or a local emergency number immediately. You can also go to the closest emergency room.

What to ask your doctor

This article describes the usual recommended dosages for metolazone oral tablet. If your doctor prescribes this medication, they’ll determine the dosage that’s best for you.

Do not change your dosage of metolazone oral tablet without your doctor’s recommendation. You should take metolazone oral tablet exactly as your doctor prescribes it. Let your doctor know if you have concerns or questions about your treatment plan.

Here’s a list of questions you may want to ask your doctor:

  • What lab work will you need to monitor while I’m taking metolazone?
  • What determines whether my dosage of metolazone is right?
  • How often will you increase my dosage of metolazone?

Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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