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Medically Approved

Lupkynis dosage: A detailed guide

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Form and strengthDosageFAQHow it's takenCouponOverdoseAsk your doctorBoxed warnings
Doctors prescribe Lupkynis for lupus nephritis in adults. It should only be used together with other drugs that weaken your immune system. You take it by mouth twice per day.
Medically reviewed by Paul Hetrick, PharmD
Updated on

This article describes Lupkynis oral capsule’s dosage and strength and gives details on how to take it. You’ll also find information on cost savings and coupon options for Lupkynis. If you want to know more about Lupkynis oral capsule, see this overview article. It covers details about the drug’s uses and side effects, ways to save on cost, and more.

Lupkynis is a brand-name medication that comes as oral capsules. Its active ingredient is voclosporin. (An active ingredient is what makes a medication work.) It isn’t available in a generic version. This article describes dosages of Lupkynis.

Boxed warnings

This drug has boxed warnings about the risks of serious infection and cancer. A boxed warning is the most serious warning from the Food and Drug Administration (FDA).

See the end of this article for more information about these warnings.

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Form and strength of Lupkynis

Lupkynis oral capsule comes as follows:

  • Form: capsule that you’ll swallow whole
  • Strength: 7.9 milligrams (mg)

Dosage of Lupkynis

This article describes the recommended dosage for Lupkynis oral capsule. The drugmaker provides these dosages.

If your doctor prescribes this medication, you should follow the dosage they prescribe. Your doctor will determine the dosage that best meets your needs. Do not change your dosage of Lupkynis oral capsule without your doctor’s recommendation.

Usual recommended dosage of Lupkynis in adults

The usual recommended dosage of Lupkynis for lupus nephritis is as follows:

  • Dose: 23.7 mg
  • Frequency: twice per day

Dosage adjustments for Lupkynis

Your doctor will prescribe a dosage of Lupkynis oral capsule based on several factors. These include:

  • how well your kidneys function
  • how well your liver functions
  • other medications you’re taking

Missed dose of Lupkynis

Talk with your doctor or pharmacist right away if you realize you forgot to take a dose of Lupkynis oral capsule. You should wait at least 8 hours between doses. Depending on timing, they may advise you to take the missed dose. Or they may advise you to skip it and take your next dose as scheduled.

For tips on how to plan your doses of Lupkynis and avoid missing a dose, read this article. You could also try:

  • downloading a reminder app on your phone
  • setting an alarm
  • putting a note where you’ll see it, such as on your calendar, bathroom mirror, or bedside table

Frequently asked questions

Below are answers to some commonly asked questions about Lupkynis oral capsule and its dosage.

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How does the dosage of Lupkynis compare with the dosage of Benlysta?

Lupkynis is a capsule that you swallow whole twice per day. Benlysta is a solution that’s given as an intravenous (IV) infusion (an injection into your vein given over time) or an injection under your skin.

An IV infusion of Benlysta is given by a healthcare professional. At first, it’s given every 2 weeks. Once established, it’s given every 4 weeks. The dosage is based on your body weight.

Benlysta may also be given as an injection under your skin. This injection is given once weekly, and it does not require a healthcare professional.

Talk with your doctor about which medication is best for you.

Is Lupkynis taken long term?

Yes, doctors can prescribe Lupkynis oral capsule as a long-term treatment. If you and your doctor find that it’s safe and effective for your condition, you’ll likely take it long term. But if you do not see improvement by 24 weeks, your doctor will likely take you off the medication.

Keep in mind, it is not known whether it’s safe and effective to take Lupkynis for longer than 1 year. If you’ve been on it for longer than that, your doctor may consider stopping the medication.

If you have questions about how long you should take Lupkynis, talk with your doctor.

How Lupkynis is taken

You’ll swallow Lupkynis oral capsule twice per day. Your doses should be taken as close as possible to 12 hours apart each day. Wait at least 8 hours between doses. The capsule must be swallowed whole on an empty stomach.

Your doctor may advise that you take this medication around the same time each day. This helps keep a consistent amount of the drug in your body. And that can help the drug work more effectively.

If it’s hard for you to swallow capsules, view this article. It provides suggestions on how to swallow medications that come in pill form.

Also, be sure to talk with your doctor or pharmacist if you’re having difficulty taking your medication. They can offer recommendations for how to take it.

Lupkynis coupon

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Note: Optum Perks coupons cannot be used with insurance copays or benefits.

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Overdose of Lupkynis

It’s important that you do not take more Lupkynis oral capsule than your doctor prescribes. Doing so can lead to harmful effects.

Symptoms of Lupkynis overdose

Symptoms of an overdose can include:

  • tremors (involuntary movements or shaking)
  • headache
  • nausea and vomiting
  • fast heartbeat
  • infections
  • fatigue or lethargy

What to do if you take too much Lupkynis

If you think you’ve taken too much Lupkynis, call your doctor or pharmacist right away. Or you could call 800-222-1222 to speak with someone at America’s Poison Centers. You can also use its online resource. If you have severe symptoms, call 911 or a local emergency number immediately. You can also go to the closest emergency room.

What to ask your doctor

This article describes the usual recommended dosage for Lupkynis oral capsule. If your doctor prescribes this medication, they’ll determine the dosage that’s best for you.

Do not change your dosage of Lupkynis oral capsule without your doctor’s recommendation. You should take Lupkynis oral capsule exactly as your doctor prescribes it. Let your doctor know if you have concerns or questions about your treatment plan.

Here’s a list of some possible questions you may want to ask your doctor:

  • How often will I need to get blood tests while I’m taking Lupkynis?
  • Am I taking any medications that would require a lower dose of Lupkynis?
  • Will decreasing my Lupkynis dose relieve any of my side effects?

Boxed warnings for Lupkynis

Lupkynis has boxed warnings about the risks of serious infection and cancer. Boxed warnings are the most serious warnings from the FDA.

Risk of serious infection: Drugs that weaken your immune system (immunosuppressants), like Lupkynis, can increase your risk of infection. These infections can be serious and life threatening. Seek medical care if you think you may be developing an infection.

Risk of cancer: Drugs that weaken your immune system (immunosuppressants), like Lupkynis, can raise your risk of developing certain cancers. These cancers are most commonly lymphoma or ones affecting the skin. Limit your sun exposure. And use sunscreen or protective clothing. Talk with your doctor if you notice any changes to your skin.

To learn more about these risks, talk with your doctor.

Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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