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Lurasidone oral tablet dosage: A detailed guide

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Doctors prescribe lurasidone oral tablet for schizophrenia and for depression related to bipolar I disorder in adults and some children. You take it by mouth once per day.
Medically reviewed by Bryson Russell, PharmD, MHSA, MSc
Updated on

This article describes lurasidone oral tablet’s dosages and strengths and gives details on how to take it. You’ll also find information on cost savings and coupon options for lurasidone. To learn more about lurasidone, talk with your doctor.

Lurasidone oral tablet is a generic version of the brand-name drug Latuda.

This drug has a boxed warning. A boxed warning is the most serious warning from the Food and Drug Administration (FDA). For details, see the end of this article.

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Form and strengths of lurasidone

Lurasidone oral tablet comes as follows:

  • Form: oral tablet that you take by swallowing
  • Strengths: 20 milligrams (mg), 40 mg, 60 mg, 80 mg, 120 mg

Dosage of lurasidone

This article describes the recommended dosages for lurasidone oral tablet. The drugmaker provides these dosages. In some cases, doctors may adjust your dosage from those shown below.

If your doctor prescribes this medication, you should follow the dosage they prescribe. Your doctor will determine the dosage that best meets your needs. Do not change your dosage of lurasidone oral tablet without your doctor’s recommendation.

Usual recommended dosages of lurasidone in adults

Usually, doctors start by prescribing a low dosage of lurasidone oral tablet. Then, they’ll adjust it over time until the right dosage is reached. Ultimately, your doctor will prescribe the smallest dosage of lurasidone oral tablet that gives the desired outcome.

Lurasidone dosage for schizophrenia

The recommended dosages of lurasidone oral tablet for schizophrenia in adults are:

  • Starting dose: 40 mg once per day
  • Maintenance dose: 40 to 160 mg once per day
  • Maximum dose: 160 mg once per day

Lurasidone dosage for bipolar depression

The recommended dosages for depression related to bipolar I disorder in adults are:

  • Starting dose: 20 mg once per day
  • Maintenance dose: 20 to 120 mg once per day
  • Maximum dose: 120 mg once per day

You need to take lurasidone oral tablet with food to help your body absorb the drug. It’s recommended that you consume at least 350 calories when you take lurasidone oral tablet.

You can take lurasidone oral tablet at any time of day. But take it at the same time each day. This will help keep a consistent level of the drug in your body.

Dosages of lurasidone in children

The recommended dosages of lurasidone oral tablet for use in children are:

Condition and ageStarting doseMaintenance doseMaximum dose
schizophrenia in adolescents ages 13 to 17 years40 mg once per day40 to 80 mg once per day80 mg once per day
bipolar depression in children and adolescents ages 10 to 17 years20 mg once per day20 to 80 mg once per day80 mg once per day

Frequently asked questions

Below are answers to some commonly asked questions about lurasidone oral tablet and its dosage.

Is there a lurasidone dosing twice daily?

No. The recommended dosing frequency of lurasidone oral tablet is once per day. You can take it at any time of day. If you’re having side effects such as sleepiness, try taking it before bed.

Follow your doctor’s directions for taking lurasidone oral tablet. Talk with your doctor or pharmacist if you have questions about how to take lurasidone oral tablet or when to take it.

Is lurasidone taken long term?

Yes, doctors typically prescribe lurasidone oral tablet as a long-term treatment. If you and your doctor determine that it’s safe and effective for your condition, you’ll likely take it long term.

If you have questions about how long you should take lurasidone oral tablet, talk with your doctor.

Lurasidone coupon

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Overdose of lurasidone

It’s important that you do not take more lurasidone oral tablet than your doctor prescribes. Doing so can lead to harmful effects.

What to do if you take too much lurasidone

If you think you’ve taken too much lurasidone, call your doctor or pharmacist right away. Or you could call 800-222-1222 to speak with someone at America’s Poison Centers. You can also use its online resource. If you have severe symptoms, call 911 or a local emergency number immediately. You can also go to the closest emergency room.

Boxed warnings for lurasidone

Lurasidone has boxed warnings about the risk of:

A boxed warning is the most serious warning from the FDA.

Risk of death in older adults with dementia-related psychosis: Older adults with dementia-related psychosis who take antipsychotic medications have a higher risk of death. (Lurasidone oral tablet is an antipsychotic medication.) Dementia is a loss of memory and thinking abilities. People with dementia can experience psychosis, which is when they lose contact with reality.

Due to this risk, lurasidone isn’t approved for use in older adults with dementia-related psychosis. 

Risk of suicidal thoughts or behaviors in children and young adults: Taking lurasidone may increase the risk of suicidal thoughts or behaviors in people ages 24 years and younger. The risk is highest in the first few months of treatment and during dosage changes. Keep in mind that depression and other mental health problems can also cause suicidal thoughts and actions.

Talk with your doctor to learn more.

Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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