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Depression and hair loss: What to know

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The linkInfluencing factorsTreatmentSummary
If you receive a diagnosis of depression, you may have a higher chance of experiencing hair loss. This link works both ways in that developing hair loss can also trigger depressive symptoms.
Medically reviewed by Yalda Safai, MD, MPH
Written by D. M. Pollock
Updated on

Depression, or major depressive disorder, is a common mental health condition that causes emotional distress, such as feelings of sadness, hopelessness, and numbness. These symptoms can become severe, affecting your ability to complete daily tasks and even stop you enjoying your hobbies or social life.

Depression may also lead to physical symptoms, including hair loss.

Hair loss can be unpleasant and may appear as thinning hair, bald patches, or a receding hairline. Experiencing this may cause psychological symptoms and can develop as a result of health conditions, emotional distress, or traumatic events. 

Hair loss and depression can often occur at the same time, and research suggests that they may cause each other.

Adult female brushing long hair over half of their face as they could be wondering if there is a link between depression and hair loss
Dmytro Betsenko/Getty Images

Depression, or major depressive disorder, is a common yet serious mental health condition. According to the World Health Organization (WHO), it affects around 5% of adults globally.

Recent research from 2019 assessed over 6 million individuals with diagnoses of depression and alopecia areata.

Alopecia is a health condition where your immune system attacks your hair follicles, causing hair loss.

This research explores the link between alopecia and depression and suggests that if you have a diagnosis of major depressive disorder, you are 90% more likely to experience hair loss.

What’s more, they noticed that this link goes both ways and if you have hair loss, you are 34% more likely to develop a major depressive disorder.

This shows the potential for experiencing hair loss to have a significant effect on your mental well-being and that depression may affect your chance of developing alopecia.

Researchers are still uncertain about the exact reasons for these links. However, the emotional strain and stress that both hair loss and depression can cause are likely to play a role in the connection. 

Factors influencing depression and hair loss

Depression causes a range of symptoms, and everyone experiences them differently. You may experience many different symptoms or just a few.

You may experience symptoms of depression that cause physiological changes that may contribute to hair loss. Certain treatments for depression may also have side effects that include hair loss.

Stress and hormonal changes

Symptoms of depression can vary greatly among individuals. Some symptoms that you may notice include:

  • irritability
  • restlessness
  • feeling on edge
  • impulsivity
  • isolation

These stressful symptoms can present as physiological effects. These may appear as the following:

  • headaches
  • racing heart
  • tightening in your chest
  • digestion problems

Feelings of stress may lead to an increased chance of developing depression, as well as sometimes presenting as a symptom of the condition.

Long-term stress, as well as the digestive problems and trouble sleeping that stress often leads to, can put you at risk of many health problems. One of which is hair loss, or telogen effluvium.

While scientists do not yet fully understand the causes of the link between stress and hair loss, recent research on the hair growth cycles of mice may help us understand. Your hair grows in three main phases:

  • growth phase (anagen)
  • degeneration, where your hair stops growing (catagen)
  • rest, where your hair sheds to make room for more growth (telogen)

During periods of stress, your body releases cortisol. This is a hormone that the adrenal glands produce. The researchers found that higher concentrations of the stress hormone cause hair follicles to remain dormant in the resting (telogen) phase.

This means that the hair is shedding without being replaced. Hair loss can be distressing, which may cause further depressive symptoms.  

Antidepressant medications

Some case reports suggest that certain antidepressant medications may also contribute to hair loss.

For example, some 2021 research noted that one patient taking escitalopram (Lexapro) noticed hair loss symptoms. Even though the drug helped their depression, the hair loss made them wish to stop taking the medication. After switching to vortioxetine (Trintellix), the hair loss improved.

And one 2017 review notes two case studies of patients noticing hair loss after taking sertraline (Zoloft). While it comments that hair loss is more likely to be an uncommon side effect of selective serotonin reuptake inhibitors (SSRIs), it recommends people taking this medication are aware of the possibility.

However, research into the link between depression and hair loss found that antidepressant use lessened the risk of experiencing hair loss in people with alopecia. This is likely because relieving the stress that comes with depression may lower the chance of stress-induced hair loss.

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Treatment

If you are experiencing both depression and hair loss, it is important to treat both. As there is a connection between the two conditions, treating one may help treat the other and vice versa.

Hair loss

There are many different causes of hair loss. If you are experiencing hair loss, it is important to speak with a doctor, as they will be able to determine the cause and, therefore, a suitable treatment.

However, there are several steps you can take to reduce your hair loss and try to encourage new growth.

These include:

  • Diet and nutrition: If you are not eating a nutritious and mineral-rich range of foods, it will not be supporting your hair growth. It is important to ensure you receive enough of the following vitamins and minerals in your diet for healthy hair:
    • vitamin C
    • vitamin B
    • vitamin E
    • iron
    • zinc
  • Topical medications: Minoxidil (Rogaine) is a topical hair growth medication that you can buy over the counter. This medication can help prolong the growth phase of your hair growth cycle.
  • Managing stress: Exercising and meditation can help lower stress levels, keep you in the present moment, and even improve your sleep.

Depression

If you receive a diagnosis of depression, it can feel daunting. However, there are plenty of different types of treatment, from medications to therapy.

For example, some treatments a doctor may recommend include:

  • Talk therapy: Speaking with a professional can help teach you how to cope with your passing thoughts and feelings. For example, cognitive behavioral therapy (CBT) can help rewire your mind and identify unhealthy ways of thinking.
  • Tricyclic antidepressants: These medications help to treat depression by boosting the amount of two neurotransmitters, serotonin and norepinephrine, in your brain. They include doxepin (Sinequan) and amitriptyline (Elavil).
  • Serotonin and norepinephrine reuptake inhibitors (SNRIs): These medications also increase the amount of these two neurotransmitters in your brain but with fewer side effects than tricyclic antidepressants. These include venlafaxine (Effexor XR).

Summary

The emotional and psychological effects of losing your hair can be severe, while depression can increase your chance of hair loss. While the link between these two conditions is well documented, researchers are still looking for the reason why.

If you receive a diagnosis of depression, it is important to be aware that certain antidepressant medications may increase your risk of hair loss. However, there are plenty of different treatment options, so if you notice signs of hair loss, you may want to speak with a doctor. They will work with you to create an alternative treatment plan.

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