Skip to main content
Medically Approved

Mydayis side effects: A detailed guide

twitter share buttonfacebook share buttonlinkedin share buttonemail article button
More common side effectsMild side effectsSerious side effectsSide effects in childrenFAQMisuseSide effects in detailWarningsAsk your doctor
Mydayis is prescribed for attention deficit hyperactivity disorder (ADHD). It’s a stimulant drug that may cause mild or serious side effects. These include trouble sleeping and risk of misuse and addiction.
Medically reviewed by Audrey Amos, PharmD
Updated on

This article describes possible side effects of Mydayis. You can explore this overview article to learn more about Mydayis, including the drug’s uses, ways to save on cost, and more.

Mydayis is a brand-name medication that comes as an extended-release capsule. It’s available in a generic version called dextroamphetamine saccharate, amphetamine aspartate monohydrate, dextroamphetamine sulfate, and amphetamine sulfate (mixed-salts of a single-entity amphetamine product).

This article describes possible side effects of Mydayis.

Boxed warning: Risk of misuse and addiction

Mydayis has a boxed warning for the risk of misuse and addiction. A boxed warning is the most serious warning from the Food and Drug Administration (FDA).

For details, see the “Misuse and Mydayis” section below.

Need a diagnosis or prescription quickly? For certain health conditions, Optum Perks offers personalized on-demand care with no appointment required. For $25, answer a few questions online and receive a diagnosis and treatment plan from a board certified healthcare professional in 15 minutes or less. Get started here.

More common side effects of Mydayis

Mydayis may cause mild or serious side effects. Below are some of the more common side effects of this medication.

Commonly reported side effects of Mydayis include:

* To learn more about this side effect, see the “Side effects of Mydayis in detail” section below.

Mild side effects of Mydayis

Mydayis may cause certain mild side effects. Typically, mild side effects are temporary and can be easily managed. Tell your doctor or pharmacist if you have side effects that don’t go away or become bothersome.

Mild side effects of Mydayis that occurred in studies include:

Mydayis may cause more mild side effects than those listed above. For details, see the drug’s prescribing information.

* To learn more about this side effect, see the “Side effects of Mydayis in detail” section below.
† An allergic reaction is possible with Mydayis. But it’s unclear whether it occurred in the drug’s studies.

Serious side effects of Mydayis

Mydayis may cause certain serious side effects. If you have any serious side effects from Mydayis, call your doctor right away. But if you think you’re having a medical emergency or your side effects feel life threatening, take immediate action. Call 911 or a local emergency number, or go to the nearest emergency room.

After the FDA approves a drug, it tracks and reviews side effects of the medication. Visit MedWatch’s website if you’d like to notify the FDA about a side effect you’ve had with Mydayis.

Serious side effects of Mydayis that occurred in studies include:

* To learn more about this side effect, see the “Side effects of Mydayis in detail” section below.
Mydayis has a boxed warning for this side effect. A boxed warning is the most serious warning from the FDA. To learn more, see the “Misuse and Mydayis” section below.
‡ An allergic reaction is possible with Mydayis. But it’s unclear whether it occurred in the drug’s studies.

Download the free Optum Perks Discount Card to save up to 80% on some prescription medications.

Pill bottle with text 'Starts at $4'

Free prescription coupons

Seriously … free. Explore prices that beat the competition 70% of the time.

Get free card

Side effects of Mydayis in children

For children, doctors prescribe Mydayis to treat ADHD. The drug is used for this purpose in children ages 13 years and older.

In studies, the following side effects were more common in children than in adults:

If you’d like to know more about side effects in children taking Mydayis, talk with your doctor or pharmacist.

Common questions about side effects of Mydayis

Here are answers to some common questions about side effects of Mydayis. If you have other questions, talk with your doctor or pharmacist.

Are side effects of Mydayis similar to those seen with Vyvanse?

Yes, the side effects of Mydayis are similar to the side effects of Vyvanse. Both of these medications are stimulant drugs that treat ADHD. Both of them are also long-acting medications. So they cause many of the same mild side effects.

This includes anxiety, decreased appetite, and weight loss. They also have many of the same serious side effects, including a boxed warning for abuse, misuse, and addiction.

You can learn more about how these two drugs compare by talking with your doctor or pharmacist.

How long do side effects of Mydayis usually last?

It depends. Many of the side effects of Mydayis are mild and temporary. They may improve or go away within a few days or weeks as your body gets used to the drug. But for some people, certain side effects may continue as long as they take Mydayis.

Talk with your doctor or pharmacist to learn more about what to expect with Mydayis. If you have side effects that don’t go away or become bothersome, talk with your doctor.

Does Mydayis cause long-term side effects?

Yes, in some cases Mydayis may cause long-term side effects. These can occur if you take the drug for a long time.

Examples of long-term side effects reported with Mydayis include:

Talk with your doctor to learn more about these side effects and how to manage them. Ask your doctor for more information about how long these side effects of Mydayis may last.

* To learn more about this side effect, see the “Side effects of Mydayis in detail” section below.
Mydayis has a boxed warning for this side effect. A boxed warning is the most serious warning from the FDA. To learn more, see the “Misuse and Mydayis” section below.

Misuse and Mydayis

Mydayis has a boxed warning for the risk of misuse and addiction. A boxed warning is the most serious warning from the FDA.

Mydayis has a high risk of misuse. This can lead to substance use problems, including addiction. Addiction refers to feeling unable to stop taking a drug, even though it may be causing harm. Addiction can lead to overdose or death.

Misusing Mydayis also increases the risk of suicidal thoughts or behaviors.

Taking Mydayis for a long time can also lead to drug dependence. With dependence, your body needs the drug in order to function like usual. Withdrawal symptoms can occur if you are dependent on a drug and you suddenly stop taking it. 

The risk of misuse and addiction may be higher in people who have misused drugs or alcohol in the past.

Talk with your doctor if you have concerns about misuse or addiction with Mydayis. If you experience misuse or addiction, tell your doctor. They’ll likely recommend ways to get help. If you have thoughts about hurting yourself, call 911.

Suicide prevention

If you or someone you know is in crisis and considering suicide or self-harm, please seek support:

If you’re calling on behalf of someone else, stay with them until help arrives. You may remove weapons or substances that can cause harm if you can do so safely.

If you are not in the same household, stay on the phone with them until help arrives.

Side effects of Mydayis in detail

Below you’ll find details on some of the side effects of Mydayis.

Decreased appetite

In studies, decreased appetite was very common in people taking Mydayis. This side effect is usually mild, but may be serious for some people.

With Mydayis, you may not feel hungry or want to eat. This is because stimulant drugs curb your appetite. For some people, it’s a temporary side effect as their body gets used to the medication. For others, it leads to unwanted weight loss.

Ways to manage

Managing appetite loss can be challenging. It’s hard to eat when a medication makes you feel like not eating. But there are some things you can try. First, try to eat a balanced meal before taking Mydayis in the morning.

Then, eat several smaller meals or snacks throughout the day. If you feel like eating more in the evening, have another nutritious meal.

If problems with appetite continue, tell your doctor. They may be able to suggest other ways to increase the amount of food or calories you eat.

Weight loss

In studies, weight loss was common in people taking Mydayis. This side effect is usually mild, but may be serious for some people.

With Mydayis, weight loss is usually due to its effect on appetite. Losing your appetite is very common with Mydayis. Some people get used to this effect or are still able to eat enough calories to maintain their weight.

Other people lose weight while taking Mydayis. This may not be a problem for some people. But for others, the weight loss isn’t wanted and their weight goes too low.

Ways to manage

To manage weight loss with Mydayis, start with the lack of appetite. Try getting as many calories as possible when the drug’s effects are lowest. For example, eat a high calorie, nutritious breakfast before taking Mydayis in the morning.

Choose calorie-dense snacks throughout the day, such as cheese, nuts, or protein bars or drinks. If the effects wear off in the evening, try to eat another larger, nutritious meal.

Tell your doctor if you’re unable to stop the weight loss or you’re having difficulty gaining back any weight. They may be able to suggest other ways to increase your intake of food and calories.

Slowed growth in children

Slowed growth in height and weight is possible with stimulant drugs, such as Mydayis. This side effect may be serious.

With slowed growth, children may not grow as tall or gain as much as weight as expected. In studies of Mydayis, weight loss was common in children.

But these studies weren’t long enough to know how it affected growth long term. With other stimulant drugs, this effect is usually temporary and children catch up on their growth.

Taking Mydayis for a long time increases the risk of having slowed growth.

Ways to manage

Due to the risk of slowed growth in children, doctors check children’s height and weight often during Mydayis treatment. They may stop Mydayis treatment if a child isn’t growing or gaining weight as expected.

If you have concerns about slowed growth in children, talk with your doctor.

Allergic reaction

For some people, Mydayis can cause an allergic reaction. But it’s not clear whether this side effect occurred in the drug’s studies.

Symptoms can be mild or serious and may include:

  • itchiness
  • skin rash
  • swelling under the skin, typically affecting eyelids, lips, hands, or feet
  • swelling of the mouth, tongue, or throat, which can make it hard to breathe
  • flushing (temporary warmth, redness, or deepening of skin color)

Ways to manage

For mild allergic reaction symptoms, such as a mild rash, call your doctor right away. They may recommend treatments to help manage your symptoms. They’ll also let you know whether you should keep taking the medication.

For severe allergic reaction symptoms, such as swelling or trouble breathing, call 911 or your local emergency number right away. These symptoms require immediate medical care because they can become life threatening. If you’ve had a serious allergic reaction to Mydayis, your doctor may recommend taking a different medication instead.

Warnings for Mydayis

Below are some factors you may want to discuss with your doctor before taking Mydayis.

Boxed warning: Risk of misuse and addiction

Mydayis has a boxed warning for the risk of misuse and addiction. A boxed warning is the most serious warning from the FDA.

For details, see the “Misuse and Mydayis” section above.

Other warnings

It may not be safe for you to take Mydayis if you have specific health conditions. These are sometimes called drug-condition interactions. Other things may also affect whether Mydayis is a safe treatment option for you.

Before taking Mydayis, tell your doctor about your health and medications you take. Things to consider include:

Mydayis and pregnancy

It’s not known whether Mydayis should be taken during pregnancy. If you’re planning a pregnancy or can become pregnant, talk with your doctor before taking this medication.

Your doctor may talk with you about a pregnancy registry. This registry monitors the outcome of taking Mydayis during pregnancy. It helps scientists learn more about the effects of Mydayis during pregnancy. You can learn more or register by visiting the website or calling 866-961-2388.

Mydayis and breastfeeding

Mydayis should not be taken while breastfeeding. If you’re currently breastfeeding or planning to do so, talk with your doctor before taking this medication. Your doctor may recommend other ways to feed your child during treatment with Mydayis.

Mydayis and alcohol

Mydayis is known to interact with alcohol.

In studies, alcohol caused a faster release of Mydayis into the body. This may cause you to absorb Mydayis faster and increase the risk of side effects, including serious side effects. Due to this risk, drinking alcohol should be avoided during Mydayis treatment.

If you drink alcohol, talk with your doctor for more information about whether it’s safe to consume it during your treatment with Mydayis.

What to ask your doctor

This article describes common and serious side effects of Mydayis. If your doctor prescribes this medication, they can discuss possible side effects with you. Let your doctor know if you have concerns or questions about treatment with this medication.

Here’s a list of some possible questions you may want to ask your doctor:

  • Do I have a higher risk of side effects than other people?
  • Does my risk of side effects depend on the dosage I take?
  • How do the side effects of Mydayis compare to those of other drugs that could treat my condition?

Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

Article resources