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Medically Approved

Myfembree dosage: A detailed guide

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Form and strengthDosageFAQHow it’s takenCouponOverdoseAsk your doctorBoxed warning
Doctors prescribe Myfembree for heavy menstrual bleeding related to uterine fibroids and pain associated with endometriosis. You take it by mouth once per day.
Medically reviewed by Elizabeth Scheffel, PharmD
Updated on

This article describes Myfembree’s dosage and strength and gives details on how to take it. You’ll also find information on cost savings and coupon options for Myfembree. If you want to know more about Myfembree, see this overview article. It covers details about the drug’s uses and side effects, ways to save on cost, and more.

Myfembree is a brand-name medication that comes as a tablet that you swallow. It isn’t available in a generic version. This article describes the dosage of Myfembree.

Boxed warning: Risk of blood clots and blood vessel disorders

Myfembree has a boxed warning for the risk of blood clots and blood vessel disorders. A boxed warning is the most serious warning from the Food and Drug Administration (FDA).

See the end of this article for more information about this warning.

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Form and strength of Myfembree

Myfembree comes as follows:

  • Form: a tablet that you swallow
  • Strength: a combination of relugolix 40 milligrams (mg), estradiol 1 mg, and norethindrone acetate 0.5 mg

Dosage of Myfembree

This article describes the recommended dosage for Myfembree. The drugmaker provides these dosages.

If your doctor prescribes this medication, you should follow the dosage they prescribe. Your doctor will determine the dosage that best meets your needs. Do not change your dosage of Myfembree without your doctor’s recommendation.

Usual recommended dosage of Myfembree in adults

Myfembree is used to manage heavy menstrual bleeding related to uterine fibroids and pain associated with endometriosis.

There is one dosage of Myfembree, which is as follows:

  • Dose: 1 tablet (relugolix 40 mg, estradiol 1 mg, and norethindrone acetate 0.5 mg)
  • Frequency: once per day

Missed dose of Myfembree

If you miss a dose of Myfembree, take it as soon as possible on the same day. Your next dose can be taken at your usual time the next day.

If you’re not sure whether you should take your missed dose, talk with your doctor or pharmacist right away. They may advise you to take the missed dose. Or they may advise you to skip it and take your next dose as scheduled.

For tips on how to plan your doses of Myfembree and avoid missing a dose, read this article. You could also try:

  • downloading a reminder app on your phone
  • setting an alarm
  • putting a note where you’ll see it, such as on your calendar, bathroom mirror, or bedside table

Frequently asked questions

Below are answers to some commonly asked questions about Myfembree and its dosage.

Can Myfembree be used for endometriosis? If so, what’s the dosage?

Myfembree is used to treat moderate to severe pain associated with endometriosis. It doesn’t treat or cure your condition. It’s for females ages 18 years and older who haven’t gone through menopause yet.

Myfembree is taken by mouth once per day. You should take it at the same time each day, with or without food. You should start it as soon as possible after the start of your period. But start it no later than 7 days after your period starts.

Talk with your doctor or pharmacist to learn more about the dosage of Myfembree for endometriosis pain.

Note: Sex and gender exist on spectrums. In this article, we use the term “female” to refer to a person’s sex assigned at birth.

How long does it take Myfembree to start working?

Myfembree starts to work within 4 weeks of starting treatment. But you may experience continued improvement for 8–12 weeks.

Talk with your doctor if you have questions or concerns about managing your symptoms with Myfembree.

Is Myfembree taken long term?

Yes, doctors typically prescribe Myfembree as a long-term treatment. If you and your doctor determine that it’s safe and effective for your condition, you can take it for up to 24 months. It’s not recommended that you take it for longer than 24 months because of the risk of permanent bone loss.

If you have questions about how long you should take Myfembree, talk with your doctor.

How Myfembree is taken

You’ll swallow Myfembree once per day.

Your doctor may advise that you take this medication around the same time each day, with or without food. This helps keep a consistent amount of the drug in your body. And that can help the drug work more effectively.

If it’s hard for you to swallow tablets, view this article. It provides suggestions on how to swallow medications that come in pill form.

Also, be sure to talk with your doctor or pharmacist if you’re having difficulty taking your medication. They can offer recommendations about taking it.

Myfembree coupon

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Overdose of Myfembree

It’s important that you do not take more Myfembree than your doctor prescribes. Doing so can lead to harmful effects.

Symptoms of Myfembree overdose

Symptoms of an overdose can include:

  • nausea or vomiting
  • breast tenderness
  • abdominal pain
  • drowsiness or fatigue
  • withdrawal bleeding

What to do if you take too much Myfembree

If you think you’ve taken too much Myfembree, call your doctor or pharmacist right away. Or you could call 800-222-1222 to speak with someone at America’s Poison Centers. You can also use its online resource. If you have severe symptoms, call 911 or a local emergency number immediately. You can also go to the closest emergency room.

What to ask your doctor

This article describes the usual recommended dosage for Myfembree. If your doctor prescribes this medication, they’ll determine the dosage that’s best for you.

Do not change your dosage of Myfembree without your doctor’s recommendation. You should take Myfembree exactly as your doctor prescribes it. Let your doctor know if you have concerns or questions about your treatment plan.

Here’s a list of some possible questions you may want to ask your doctor:

  • Can I take Myfembree at the same time as my other medications?
  • What lab work needs to be monitored while I’m taking Myfembree?
  • When should I stop taking Myfembree if I’m having surgery or getting a procedure?

Boxed warning for Myfembree

Myfembree has a boxed warning for the risk of blood clots and blood vessel disorders. A boxed warning is the most serious warning from the Food and Drug Administration (FDA).

Blood clots and blood vessel disorders: Myfembree increases your risk of having a blood clot in your limb (deep vein thrombosis) or lung (pulmonary embolism). The blood clot can also travel to your heart or brain, causing a heart attack or a stroke. Those who are most at risk of this problem are people older than 35 years who smoke. People with high blood pressure, high cholesterol, or circulatory issues are also at high risk.

If you suspect you have a blood clot or blood vessel disorder, stop taking Myfembree and get medical attention.

Talk with your doctor to learn more about this risk.

Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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