This article describes possible interactions with Mounjaro. Interactions can cause a drug to have a different effect on the body than expected. Interactions can occur due to medications, alcohol, or certain health conditions.
Mounjaro comes as a solution inside a pre-filled syringe or single-dose vial for injection under your skin.
Mounjaro has a boxed warning. A boxed warning is the most serious warning from the Food and Drug Administration (FDA). For details, see the end of this article.
Need a diagnosis or prescription quickly? For certain health conditions, Optum Perks offers personalized on-demand care with no appointment required. For $25, answer a few questions online and receive a diagnosis and treatment plan from a board certified healthcare professional in 15 minutes or less. Get started here.
Other drugs and Mounjaro
The drugs in the list below may interact with Mounjaro. This article doesn’t include all drugs that may interact with Mounjaro.
Drug classes or drugs that may interact with Mounjaro include:
- other medications you take by mouth
- birth control pills
- insulin drugs
- sulfonylureas
- drug examples: glipizide (Glucotrol XL), glimepiride (Amaryl)
- what might happen: can increase the risk of low blood sugar as a side effect of Mounjaro or the sulfonylurea drug
For more information about drugs that may interact with Mounjaro and what drugs you cannot take with Mounjaro, talk with your doctor or pharmacist.
Download the free Optum Perks Discount Card to save up to 80% on some prescription medications.
When to avoid Mounjaro
Certain health conditions or other factors could increase some risks with Mounjaro. Because of this, doctors may not prescribe Mounjaro in these cases. These health conditions or other factors are called contraindications.
Here’s a list of contraindications for Mounjaro:
- Personal or family history of medullary thyroid carcinoma (MTC): To learn more, see the “Boxed warning” section at the end of this article.
- If you have multiple endocrine neoplasia syndrome type 2 (MEN2): To learn more, see the “Boxed warning” section at the end of this article.
- Past allergic reaction to Mounjaro: If you’ve ever had an allergic reaction to Mounjaro, using it again may cause another allergic reaction.
Before you start using Mounjaro, tell your doctor if anything listed above relates to you. They can recommend whether you should use Mounjaro.
Alcohol and Mounjaro
Mounjaro is not known to interact with alcohol.
However, your doctor may suggest limiting alcohol consumption while using Mounjaro. Alcohol can affect blood sugar levels, and Mounjaro is prescribed to treat high blood sugar caused by type 2 diabetes. Consuming alcohol can make it difficult to determine how well Mounjaro is working to manage your blood sugar level.
If you drink alcohol, talk with your doctor about whether it’s safe to consume it while using Mounjaro.
Other interactions and Mounjaro
Interactions can occur with supplements, foods, vaccines, and some lab tests. Below you can learn whether Mounjaro has these interactions.
The information below doesn’t include all other possible interactions with Mounjaro.
Mounjaro and supplements
Before using Mounjaro, tell your doctor and pharmacist about any herbs you take, as well as vitamins and supplements. Doing so may help you avoid interactions.
It’s important to note that Mounjaro may interact with any supplement you take by mouth. Mounjaro can cause your body to absorb less of any supplement that is taken by mouth. This can lower the effect of the supplement.
If you have questions about interactions that may affect you, talk with your doctor or pharmacist.
Mounjaro interactions with herbs
Interactions between Mounjaro and specific herbal supplements haven’t been reported. But Mounjaro could interact with any supplement taken by mouth. This includes herbal supplements taken by mouth. Mounjaro may lessen the effect of the herbal supplement.
In addition, certain herbal supplements may affect your blood sugar. For example, certain herbal supplements may reduce blood sugar levels and raise the risk of low blood sugar if they’re taken with Mounjaro.
Because of this, ask your doctor or pharmacist before taking any of these products while using Mounjaro.
Mounjaro interactions with vitamins
Interactions between Mounjaro and specific vitamins haven’t been reported. But Mounjaro could interact with any supplement taken by mouth, including vitamins. Mounjaro could lessen the effect of the supplement by lowering how much of the vitamin your body absorbs.
Because of this, ask your doctor or pharmacist before taking any vitamin supplements while using Mounjaro.
Mounjaro and food
Mounjaro isn’t known to interact with foods. But this doesn’t mean interactions with foods can’t happen or won’t be identified later.
Because of this, talk with your doctor or pharmacist about what foods you should avoid while using Mounjaro.
Mounjaro and vaccines
Mounjaro isn’t known to interact with any vaccines. But this doesn’t mean interactions with vaccines can’t happen or won’t be identified later.
Because of this, talk with your doctor or pharmacist before receiving any vaccines while using Mounjaro.
Mounjaro and lab tests
Mounjaro isn’t known to interact with lab tests. But this doesn’t mean interactions with lab tests can’t happen or won’t be identified later.
Because of this, talk with your doctor or pharmacist before having any lab tests performed while you’re using Mounjaro.
Mounjaro and cannabis or CBD
Mounjaro isn’t known to interact with cannabis (commonly called marijuana) or cannabis products such as cannabidiol (CBD). But this doesn’t mean interactions can’t happen or won’t be identified later.
As with any drug or supplement, tell your doctor before taking cannabis with Mounjaro.
Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees.
Health factors and Mounjaro
Certain medical conditions or other health factors may increase the risk of interactions with Mounjaro. Keep in mind that interactions could lead to side effects or affect how well the drug works. Before using Mounjaro, tell your doctor about your health history. They’ll determine whether Mounjaro is right for you.
These health conditions or other factors might interact with Mounjaro:
Preventing Mounjaro interactions
You may be able to help avoid certain interactions with Mounjaro. Before using this drug, you may want to discuss possible interactions with your doctor and pharmacist.
Things to consider include:
- Whether you drink alcohol or use cannabis.
- Other medications and herbs you take, as well as vitamins and supplements. Your doctor or pharmacist can help you fill out a medication list.
- What to do if you’re prescribed a new drug while using Mounjaro.
Using Mounjaro exactly as prescribed can also help prevent interactions.
Boxed warning for Mounjaro
Mounjaro has a boxed warning for the risk of thyroid cancer. A boxed warning is the most serious warning from the FDA.
It has been reported that Mounjaro and similar drugs caused an increased risk of thyroid cancer in animal studies. However, animal studies don’t always predict what would happen in humans. It’s not currently known whether Mounjaro can also raise the risk of thyroid cancer when used in humans.
Because of this risk, doctors usually won’t prescribe Mounjaro if you:
Symptoms of thyroid cancer include a hoarse voice, a lump in your throat, and neck pain. Let your doctor know immediately if you notice these or other symptoms of thyroid cancer while using Mounjaro.
To learn more, talk with your doctor.
Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking or using any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
