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Does ibuprofen raise blood pressure?

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Can I take it?Ibuprofen alternativesNSAIDs and blood pressureDrug safetyGetting medical adviceSummary
You may notice your blood pressure rise after taking ibuprofen. If you have high blood pressure (hypertension) or are at risk of developing the condition, caution is vital when taking most anti-inflammatory drugs.
Medically reviewed by Carissa Stephens, R.N., CCRN, CPN
Updated on

Nonsteroidal anti-inflammatory drugs (NSAIDs) are typically the medication of choice for pain and inflammation relief.

Though NSAIDs are effective pain relievers (analgesics), they may be unsuitable for you, especially if you have high blood pressure.

Can I take ibuprofen if I have high blood pressure?

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Ibuprofen may not be safe for some people with hypertension.

In a 2017 trial including 444 participants, researchers found that participants taking ibuprofen noticed a significant rise in their blood pressure, which could increase the risk of cardiovascular diseases and other complications.

Also, ibuprofen may interact with and alter the effectiveness of some medications, especially if you take multiple prescription drugs for chronic conditions.

A 2021 report from the American College of Cardiology stated that NSAIDs are among the top three medications that can increase blood pressure but did not specifically study ibuprofen.

Additionally, according to a 2017 article, doctors should prescribe fewer NSAIDs to patients, particularly older adults with cardiovascular disease risk.

Taking ibuprofen requires caution if you have high blood pressure, and you should always seek advice from a doctor or other healthcare professional before taking it.

However, when it comes to ibuprofen, in particular, more research is needed to confirm its effect on blood pressure.

Which anti-inflammatory can someone with high blood pressure take?

Medical experts do not typically recommend taking anti-inflammatory drugs if you are at risk of or have high blood pressure, due to its potential to either trigger a rise in blood pressure or make the condition worse.

Doctors typically suggest alternatives such as acetaminophen. Yet it’s important to note that acetaminophen may also not be the best choice for some individuals.

In a 2022 study, researchers found that regular acetaminophen intake may increase systolic blood pressure by 5 millimeters of mercury (mmHg) in people with hypertension. Systolic blood pressure is the first number in a blood pressure reading and indicates the amount of pressure your blood exerts against artery walls with every heartbeat.

It’s important to note that larger studies are needed to confirm these effects. In addition, more research including People of Color is needed, since the 2022 study discussed above involved only white people.

It’s best to consult your doctor or healthcare professional before taking any medication to help prevent the risk of developing complications related to a rise in blood pressure.

Is there an anti-inflammatory that does not raise blood pressure?

Aspirin is an anti-inflammatory drug that, according to a 2014 research summary, does not raise blood pressure.

But aspirin may not be suitable if you have multiple medical conditions. For instance, doctors do not recommend aspirin for individuals with peptic ulcer disease or asthma because it can worsen these conditions.

Most anti-inflammatory medications typically have an effect on blood pressure, to varying degrees. These effects may be different for each person.

That’s why speaking with a doctor or healthcare professional is crucial before taking any anti-inflammatory medication if you are at risk of or have high blood pressure. They can recommend the most appropriate medication that fits your personal medical history.

About high blood pressure and drug safety

Individuals taking high blood pressure medications must consider both drug effectiveness and safety. High blood pressure medications may work well, but a 2018 study found that some other medications can interact with hypertension drugs.

High blood pressure treatment requires strict management within a narrow blood pressure range, so it is essential to monitor your blood pressure regularly. If your blood pressure drops considerably while taking antihypertensive medications, it can cause dizziness, nausea, blurry vision, and fainting spells.

If you notice any of these symptoms or significant blood pressure changes, consult a doctor. They may need to adjust your medication dosage.

Additionally, as ibuprofen can increase blood pressure and the risk of cardiovascular disease, you should take it with caution if you have hypertension and take medication for high blood pressure.

If you take ibuprofen and notice your blood pressure increasing despite taking antihypertensive medications, it’s best to stop taking the ibuprofen and contact a doctor as soon as possible.

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Discussing high blood pressure with a doctor 

When discussing high blood pressure with a doctor or a healthcare professional, consider asking questions related to the severity of your high blood pressure, what the cause could be, and the most appropriate treatment for you.

Diet and lifestyle modifications are typically the initial methods recommended for preventing and managing mild cases of high blood pressure, especially if it is stress induced.

Also, discuss with your doctor the types of medications that can increase your blood pressure, like some anti-inflammatories, and which to avoid. Be sure to alert your doctor if you have other chronic medical conditions and any medication history.

Doctors and healthcare professionals typically combine findings from your clinical history and a physical examination to decide on the appropriate treatment for you.

Summary

You could notice a rise in your blood pressure after taking ibuprofen. This is because some anti-inflammatory drugs may trigger an increase in blood pressure or worsen already high blood pressure.

Doctors do not typically recommend ibuprofen or other NSAIDs if you have high blood pressure. Consult a doctor before taking anti-inflammatory drugs.

Doctors typically consider an individual’s clinical and medication history to decide the most appropriate medication to prescribe. As a result, it is crucial to inform a doctor if you are taking medications for chronic medical conditions. 

Download the free Optum Perks Discount Card to save up to 80% on some prescription medications.

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