Your kidneys perform the essential work of removing toxins, waste products, and excess fluid from your blood. They also play an important part in red blood cell production and maintaining healthy blood pressure.
When your kidneys are no longer performing this work at an ideal level, you may develop kidney disease. Most people with a condition are unaware that they have it.
Several treatment options can help with kidney disease, such as following a kidney-healthy diet and taking medication to help slow the disease progression.
What are the signs of kidney disease?

Kidney disease can start without symptoms. According to the Centers for Disease Control and Prevention (CDC), more than 1 in 7 U.S. adults have kidney disease, and most don’t know they have it.
Several signs can help you identify whether you have kidney disease, according to the National Kidney Foundation (NKF). Although these only typically occur after you’ve had the condition for some time.
You might experience:
- fatigue
- trouble concentrating
- problems sleeping
- dry or itchy skin
- blood in urine
- increased urination
- foamy urine
- puffiness around the eyes
- swollen ankles and feet
- poor appetite
- muscle cramping
According to the NKF, these symptoms don’t always show up until the disease has progressed toward the late stages, where there are high amounts of protein in the urine or the kidneys are failing.
You might only find out that you have kidney disease if a doctor does a blood or urine test to check for the condition.
How is kidney disease diagnosed?
If you’re at high risk of kidney disease, a doctor might recommend regular testing for kidney disease. The two most common ways of checking for the condition are:
- a urine albumin-creatinine ratio (uACR) test
- your estimated glomerular filtration rate (eGFR)
The uACR test measures the amount of a protein called albumin in the urine. If the kidneys are working as usual, there should be no albumin in the urine.
An eGFR value can estimate how well your kidneys are filtering blood. Your body naturally produces a waste product called creatinine during the process of breaking down muscles.
Kidneys filter out creatinine from the blood. High creatinine levels in the blood can mean the kidneys are not filtering as well as they should be.
Doctors use these tests to monitor the progress of kidney disease. If the treatment is working, your eGFR should stay the same, and the urine albumin should either stay the same or decrease.
Treatment options
If you have a diagnosis of kidney disease, you can take several steps to help manage the condition. A healthcare professional may recommend medications and lifestyle measures to help stop or slow the progression of kidney disease.