This article describes possible interactions with carisoprodol oral tablet. Interactions can cause a drug to have a different effect on the body than expected. Interactions can occur due to medications, alcohol, or certain health conditions.
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Other drugs and carisoprodol
The drugs in the list below may interact with carisoprodol oral tablet. This article doesn’t include all drugs that may interact with carisoprodol.
Drug classes or drugs that may interact with carisoprodol oral tablet include:
- benzodiazepines:
- drug examples: alprazolam (Xanax), lorazepam (Ativan)
- what might happen: can increase the risk of side effects of carisoprodol and the benzodiazepine, like sleepiness
- opioids:
- certain antidepressants:
- drug examples: amitriptyline, nortriptyline (Pamelor)
- what might happen: can increase the risk of side effects of carisoprodol and the antidepressant, like sleepiness
- certain allergy medications:
- drug examples: diphenhydramine (Benadryl), cetirizine (Zyrtec)
- what might happen: can increase the risk of side effects of carisoprodol and the allergy medication, like sleepiness
- sedatives:
- drug examples: eszopiclone (Lunesta), zolpidem (Ambien)
- what might happen: can increase the risk of side effects of carisoprodol and the sedative, like sleepiness
- certain Parkinson’s disease medications:
- drug examples: entacapone (Comtan), tolcapone (Tasmar)
- what might happen: can increase the risk of side effects of carisoprodol, like dizziness and sleepiness
- certain antiepileptic drugs:
- drug examples: pregabalin (Lyrica), gabapentin (Neurontin, others)
- what might happen: can increase the risk of side effects of carisoprodol and the antiepileptic, like sleepiness
- meprobamate:
- what might happen: can increase the risk of side effects of carisoprodol
- omeprazole (Prilosec):
- what might happen: can increase the risk of side effects of carisoprodol
- clozapine (Clozaril):
- what might happen: can increase the risk of side effects of carisoprodol, like slowed breathing and low blood pressure
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Get free cardWhen to avoid carisoprodol
Certain health conditions or other factors could increase some risks with carisoprodol oral tablet. Because of this, doctors may not prescribe carisoprodol in these cases. These health conditions or other factors are called contraindications.
Here’s a list of carisoprodol contraindications:
- Acute intermittent porphyria. If you have a history of acute intermittent porphyria (a rare inherited blood condition), taking carisoprodol oral tablet may worsen your condition.
- Past allergic reaction to a group of medications called carbamates. If you’ve ever had an allergic reaction to a carbamate medication, like felbamate (Felbatol) or methocarbamol (Robaxin), taking carisoprodol may cause another allergic reaction.
Before you start taking Carisoprodol, tell your doctor if anything listed above relates to you. They can recommend whether you should take carisoprodol.
Alcohol and carisoprodol
Carisoprodol oral tablet is known to interact with alcohol.
Taking carisoprodol oral tablet and drinking alcohol may cause:
- dizziness
- sleepiness
Talk with your doctor if you have any questions about carisoprodol interactions with alcohol.
Other interactions and carisoprodol
Interactions can occur with supplements, foods, vaccines, and some lab tests. Below you can learn whether carisoprodol oral tablet has these interactions.
The information below doesn’t include all other possible interactions with carisoprodol.
Carisoprodol and supplements
Before taking carisoprodol oral tablet, tell your doctor and pharmacist about any herbs you take, as well as vitamins and supplements. Doing so may help you avoid interactions.
If you have questions about interactions that may affect you, talk with your doctor or pharmacist.
Carisoprodol interactions with herbs
Carisoprodol oral tablet may interact with St. John’s Wort. Some people take this herb to ease symptoms of depression. But taking carisoprodol and St. John’s Wort may reduce the effectiveness of carisoprodol. This is because St. John’s Wort may reduce the levels of carisoprodol in your blood.
Carisoprodol oral tablet may also interact with valerian root. Some people take this herb as a sleeping aid. But taking carisoprodol and valerian root may lead to more dizziness, sleepiness, and impaired judgment and coordination.
Because of this, ask your doctor or pharmacist before taking any of these products while taking carisoprodol oral tablet.
Carisoprodol interactions with vitamins
Carisoprodol oral tablet is not known to interact with any vitamins. But this doesn’t mean interactions with vitamins can’t happen or won’t be identified later.
Because of this, ask your doctor or pharmacist before taking any of these products while taking carisoprodol oral tablet.
Carisoprodol and food
Carisoprodol oral tablet is not known to interact with foods. But this doesn’t mean interactions with foods can’t happen or won’t be identified later.
Because of this, talk with your doctor or pharmacist about what foods you should avoid while taking carisoprodol oral tablet.
Carisoprodol and vaccines
Carisoprodol oral tablet is not known to interact with any vaccines. But this doesn’t mean interactions with vaccines can’t happen or won’t be identified later.
Because of this, talk with your doctor or pharmacist before receiving any vaccines while taking carisoprodol oral tablet.
Carisoprodol and lab tests
Carisoprodol oral tablet is not known to interact with lab tests. But this doesn’t mean interactions with lab tests can’t happen or won’t be identified later.
Because of this, talk with your doctor or pharmacist before having any tests while taking carisoprodol oral tablet.
Carisoprodol and cannabis or CBD
Reports have shown cannabis (commonly called marijuana) and cannabis products may interact with carisoprodol. Cannabidiol (CBD) is an example of a cannabis product.
Taking carisoprodol and cannabis may lead to extreme sedation and sleepiness.
Before you take carisoprodol, tell your doctor and pharmacist if you use cannabis. Doing so may help prevent possible interactions.
Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees.
Health factors and carisoprodol
Certain medical conditions or other health factors may increase the risk of interactions with carisoprodol oral tablet. Keep in mind that interactions could lead to side effects or affect how well the drug works. Before starting Carisoprodol treatment, tell your doctor about your health history. They’ll determine whether carisoprodol is right for you.
These health conditions or other factors might interact with carisoprodol oral tablet:
- history of acute intermittent porphyria (a rare inherited blood condition)*
- kidney problems
- reduced CYP2C19 activity (CYP2C19 is an enzyme that helps your body process carisoprodol)
- liver problems
- pregnancy or breastfeeding
- past allergic reaction to carisoprodol or carbamate medications*
*For more details about this health condition interaction, see the “When to avoid carisoprodol” section.
Preventing carisoprodol interactions
You may be able to help avoid certain interactions with carisoprodol oral tablet. Before taking this drug, you may want to discuss possible interactions with your doctor and pharmacist.
Things to consider include:
- Whether you drink alcohol or use cannabis.
- Other medications and herbs you take, as well as vitamins and supplements. Your doctor or pharmacist can help you fill out a medication list.
- What to do if you’re prescribed a new drug while taking carisoprodol oral tablet.
Taking carisoprodol exactly as prescribed can also help prevent interactions.
What to ask your doctor
If you have questions about carisoprodol and possible interactions, talk with your doctor.
Questions you may want to ask your doctor include:
- Can I still take carisoprodol even if it interacts with a health condition I have?
- Do other drugs used for my condition have similar interactions?
- Should I let you know if I make lifestyle changes, such as my diet or exercise routine?
Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.