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Bactrim dosage: A detailed guide

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Doctors prescribe Bactrim for certain types of bacterial infections in adults and some children. Typically, you take it by mouth two times per day.
Medically reviewed by Melissa Badowski, PharmD, MPH, FCCP
Updated on

This article describes Bactrim’s dosages and strengths and gives details on how to take it. You’ll also find information on cost savings and coupon options for Bactrim. If you want to know more about Bactrim, see this overview article. It covers details about the drug’s uses and side effects, ways to save on cost, and more.

Bactrim is a brand-name medication that comes as an oral tablet. It’s available in a generic version called sulfamethoxazole trimethoprim. This article describes dosages of Bactrim.

Form and strengths of Bactrim

Bactrim comes as follows:

  • Form: tablet that you swallow
  • Strengths:
    • 400 milligrams (mg) sulfamethoxazole/80 mg trimethoprim
    • 800 mg sulfamethoxazole/160 mg trimethoprim

Dosage of Bactrim

This article describes the recommended dosages for Bactrim. The drugmaker provides these dosages.

If your doctor prescribes this medication, you should follow the dosage they prescribe. Your doctor will determine the dosage that best meets your needs. Do not change your dosage of Bactrim without your doctor’s recommendation.

Usual recommended dosages of Bactrim in adults

Bactrim is approved to treat certain types of bacterial infections in adults.

Your doctor will determine how long you need to take Bactrim. This will depend on what type of infection you have and how severe it is.

The following table contains the recommended dosages of Bactrim.

PurposeRecommended doseFrequency
treat urinary tract infection (UTI)1 Bactrim double strength (DS) tablet* or 2 Bactrim tablets†twice per day
treat shigellosis1 Bactrim DS tablet* or 2 Bactrim tablets†twice per day
treat chronic bronchitis flare-ups1 Bactrim DS tablet or 2 Bactrim tabletstwice per day
treat pneumocystis pneumonia your doctor will determine your dose based on your body weightfour times per day
prevent Pneumocystis pneumonia1 Bactrim DS tabletonce per day
treat traveler’s diarrhea1 Bactrim DS tablet or 2 Bactrim tabletstwice per day

*Bactrim double strength (DS) tablets contain 800 milligrams (mg) sulfamethoxazole/160 mg trimethoprim.
†Bactrim tablets contain 400 mg sulfamethoxazole/80 mg trimethoprim.

Dosages of Bactrim in children

Bactrim is approved to treat certain bacterial infections in some children. This includes children ages 2 months and older. Children under the age of 2 months should not take Bactrim.

The following table contains the recommended dosages of Bactrim in milligrams (mg) and kilograms (kg).*

PurposeRecommended doseFrequency
treat urinary tract infection (UTI)40 mg/kg of body weight sulfamethoxazole and 8 mg/kg of body weight trimethoprimdivided into two doses throughout the day
treat shigellosis40 mg/kg of body weight sulfamethoxazole and 8 mg/kg of body weight trimethoprimdivided into two doses throughout the day
treat middle ear infection40 mg/kg of body weight sulfamethoxazole and 8 mg/kg of body weight trimethoprimdivided into two doses throughout the day
treat pneumocystis pneumonia75–100 mg/kg of body weight sulfamethoxazole and 15–20 mg/kg of body weight trimethoprimdivided into four doses throughout the day
prevent pneumocystis pneumoniayour child’s doctor will determine the dose based on your child’s height and body weighttwice per day

* For reference, 1 kg is about 2.2 pounds (lb). The unit mg/kg represents milligrams per kilogram.

Dosage adjustments for Bactrim

Your doctor will prescribe a dosage of Bactrim based on several factors. These include:

  • the specific condition being treated and how severe it is
  • other health conditions you may have
  • body weight (in children and some adults)

Missed dose of Bactrim

Talk with your doctor or pharmacist right away if you realize you forgot to take a dose of Bactrim. They may advise you to take the missed dose. Or they may advise you to skip it and take your next dose as scheduled.

For tips on how to plan your doses of Bactrim and avoid missing a dose, read this article. You could also try:

  • downloading a reminder app on your phone
  • setting an alarm
  • putting a note where you’ll see it, such as on your calendar, bathroom mirror, or bedside table

Frequently asked questions

Below are answers to some commonly asked questions about Bactrim and its dosage.

Is there a 3-day dosage of Bactrim for a urinary tract infection (UTI)?

It’s possible. However, the recommended dosage of Bactrim for a UTI is 1 Bactrim double strength (DS) tablet* or 2 Bactrim tablets† twice per day for 10–14 days.

In some cases, doctors may prescribe Bactrim for 3 days. If you have questions about how long you need to take Bactrim, talk with your doctor.

*Bactrim double strength (DS) tablets contain 800 milligrams (mg) sulfamethoxazole/160 mg trimethoprim.
†Bactrim tablets contain 400 mg sulfamethoxazole/80 mg trimethoprim.

Is Bactrim taken long term?

No, doctors don’t typically prescribe Bactrim as a long-term treatment. It’s usually recommended for short-term use.

If you have questions about how long you should take Bactrim, talk with your doctor.

How Bactrim is taken

You’ll typically swallow Bactrim oral tablet twice per day, or as prescribed by your doctor. You can take the drug with or without food. Taking it with food can lower your risk of stomach upset.

Your doctor may advise that you take this medication around the same time each day. This helps keep a consistent amount of the drug in your body. And that can help the drug work more effectively.

The drugmaker hasn’t specified whether Bactrim tablets can be cut, crushed, or dissolved. If it’s hard for you to swallow tablets, view this article. It provides suggestions on how to swallow medications that come in pill form.

Also, be sure to talk with your doctor or pharmacist if you’re having difficulty taking your medication. They can offer recommendations about taking it.

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Overdose of Bactrim

It’s important that you do not take more Bactrim than your doctor prescribes. Doing so can lead to harmful effects.

Symptoms of Bactrim overdose

Symptoms of an overdose can include:

What to do if you take too much Bactrim

If you think you’ve taken too much Bactrim, call your doctor or pharmacist right away. Or you could call 800-222-1222 to speak with someone at America’s Poison Centers. You can also use its online resource. If you have severe symptoms, call 911 or a local emergency number immediately. You can also go to the closest emergency room.

What to ask your doctor

This article describes the usual recommended dosages for Bactrim. If your doctor prescribes this medication, they’ll determine the dosage that’s best for you.

Do not change your dosage of Bactrim without your doctor’s recommendation. You should take Bactrim exactly as your doctor prescribes it. Let your doctor know if you have concerns or questions about your treatment plan.

Here’s a list of some possible questions you may want to ask your doctor:

  • Will a higher dosage of Bactrim increase my risk of side effects?
  • How long do I need to take Bactrim?
  • Will you be changing my dosage of Bactrim if I take other drugs with it?

Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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