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Overview
This article describes possible interactions with amlodipine oral tablet. Interactions can cause a drug to have a different effect on the body than expected. Interactions can occur due to medications, alcohol, or certain health conditions.
Other drugs and amlodipine
Before taking an amlodipine oral tablet, tell your doctor and pharmacist about any prescription, over-the-counter, or other drugs you take. Doing so may help prevent possible interactions. If you’re concerned about possible interactions, talk with your doctor or pharmacist.
Drugs that may interact with amlodipine oral tablet are listed below. This article doesn’t include all drugs that may interact with amlodipine.
Drug classes or drugs that may interact with amlodipine oral tablet include:
- nonsteroidal anti-inflammatory drugs (NSAIDs):
- drug examples: ibuprofen (Advil, Motrin) and meloxicam (Mobic)
- what might happen: an increased risk of NSAID side effects, which may lead to high blood pressure
- certain statin drugs:
- drug examples: simvastatin (Zocor) and lovastatin (Altoprev)
- what might happen: an increased risk of statin side effects, such as severe muscle pain or weakness
- certain opioid drugs:
- drug examples: hydrocodone (Hysingla ER) and oxycodone (Oxycontin and others)
- what might happen: an increased risk of opioid side effects, such as sleepiness or respiratory depression (slow or shallow breathing)
- certain immunosuppressant drugs:
- drug examples: cyclosporine (Gengraf, Neoral, Sandimmune) and tacrolimus (Astagraf XL, Envarsus XR, Prograf)
- what might happen: an increased risk of immunosuppressant side effects, such as infection
- certain phosphodiesterase type 5 (PDE5) inhibitor drugs:
- drug examples: avanafil (Stendra) and sildenafil (Liqrev, Revatio, Viagra)
- what might happen: an increased risk of low blood pressure as a side effect of amlodipine and PDE5 inhibitors
- certain antifungal drugs:
- drug examples: itraconazole (Sporanox, Tolsura) and fluconazole (Diflucan)
- what might happen: an increased risk of amlodipine side effects, such as low blood pressure or swelling and fluid buildup
- certain antibiotic drugs:
- drug examples: clarithromycin and ciprofloxacin (Cipro)
- what might happen: an increased risk of amlodipine side effects, such as low blood pressure or swelling and fluid buildup
When to avoid amlodipine
Certain health conditions or other factors could increase some risks with amlodipine oral tablet. Because of this, doctors may not prescribe amlodipine in these cases. These health conditions or other factors are called contraindications.
Here’s a contraindication for amlodipine oral tablet:
- Past allergic reaction to amlodipine. If you’ve had an allergic reaction to amlodipine oral tablet in the past, taking amlodipine may cause another allergic reaction.
Before starting treatment with amlodipine, tell your doctor if you’ve had an allergic reaction to amlodipine oral tablet. They can recommend whether you should take it.
Alcohol and amlodipine
Amlodipine oral tablet is not known to interact with alcohol.
If you drink alcohol, talk with your doctor about whether it’s safe to consume it while taking amlodipine oral tablet.
Other interactions and amlodipine
Interactions can occur with supplements, foods, vaccines, and some lab tests. Below you can learn whether amlodipine oral tablet has these interactions.
The information below doesn’t include all other possible interactions with amlodipine.
Amlodipine and supplements
Before taking an amlodipine oral tablet, tell your doctor and pharmacist about any supplements, herbs, and vitamins you take. Doing so may help you avoid possible interactions.
Amlodipine oral tablet may interact with fish oil supplements. Some people take these supplements to lower blood pressure and for other uses. Amlodipine also lowers blood pressure. So, taking amlodipine and fish oil supplements together may lead to very low blood pressure.
Because of this, you should talk with your doctor or pharmacist before taking fish oil and other supplements with amlodipine oral tablet. They can tell you whether it’s safe to take them together.
If you have questions about interactions that may affect you, talk with your doctor or pharmacist.
Amlodipine and herbs
Amlodipine oral tablet may interact with St. John’s wort. Some people use this herb for depression and other conditions.
Taking amlodipine and St. John’s wort may lead to a low level of amlodipine in your body. This could cause amlodipine to be less effective for your condition.
Because of this, you should talk with your doctor or pharmacist before taking St. John’s wort or any other herbs with amlodipine oral tablet. They can tell you whether it’s safe to take them together.
Amlodipine and vitamins
Amlodipine oral tablet isn’t known to interact with any vitamins. But this doesn’t mean interactions with vitamins can’t happen or won’t be identified later.
Because of this, ask your doctor or pharmacist before taking any vitamins while taking amlodipine oral tablet.
Amlodipine and food
Amlodipine oral tablet isn’t known to interact with foods. But this doesn’t mean interactions with foods can’t happen or won’t be identified later.
Because of this, talk with your doctor or pharmacist about what foods you should avoid while taking amlodipine oral tablet.
Amlodipine and vaccines
Amlodipine oral tablet isn’t known to interact with any vaccines. But this doesn’t mean interactions with vaccines can’t happen or won’t be identified later.
Because of this, talk with your doctor or pharmacist before receiving any vaccines while taking amlodipine oral tablet.
Amlodipine and lab tests
Amlodipine oral tablet isn’t known to interact with lab tests. But this doesn’t mean interactions with lab tests can’t happen or won’t be identified later.
Because of this, talk with your doctor or pharmacist before having any lab tests while taking amlodipine oral tablet.
Amlodipine and cannabis or CBD
Amlodipine oral tablet isn’t known to interact with cannabis (commonly called marijuana) or cannabis products such as cannabidiol (CBD). But this doesn’t mean interactions can’t happen or won’t be identified later.
As with any drug or supplement, tell your doctor before taking cannabis or CBD with amlodipine.
Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees.
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Get free cardHealth factors and amlodipine
Certain medical conditions or other health factors may increase the risk of interactions with amlodipine oral tablet. Keep in mind that interactions could lead to side effects or affect how well the drug works.
Before taking amlodipine, tell your doctor about your health history. They’ll determine whether amlodipine is right for you.
These health conditions or other factors that might interact with amlodipine oral tablet:
- liver problems, such as liver failure
- pregnancy or breastfeeding
- past allergic reaction to amlodipine
Questions about amlodipine and interactions
Here you’ll find answers to some common questions about amlodipine and possible interactions.
Do bananas and amlodipine interact?
No, amlodipine oral tablet isn’t known to interact with bananas.
Amlodipine oral tablet is prescribed to treat certain heart problems and high blood pressure. Certain other medications used for these conditions may interact with foods that are high in potassium, such as bananas. But amlodipine doesn’t have this interaction.
If you have other questions about amlodipine and certain foods, talk with your doctor or pharmacist.
What painkillers can I take with amlodipine?
Your doctor or pharmacist can recommend pain relievers that are safe to take with an amlodipine oral tablet. For example, they may advise you to take acetaminophen (Tylenol) for pain relief during amlodipine treatment. This drug isn’t known to interact with amlodipine.
However, other drugs used to relieve pain are known to interact with amlodipine oral tablet. Your doctor or pharmacist will likely advise you to avoid these drugs while taking amlodipine, including:
- NSAIDs, such as ibuprofen (Advil, Motrin) and meloxicam (Mobic)
- certain opioid drugs, such as hydrocodone (Hysingla ER) and oxycodone (Oxycontin, Xtampza ER, others)
Talk with your doctor or pharmacist before taking any pain medications during treatment with amlodipine oral tablet.
Preventing amlodipine interactions
You may be able to help avoid certain interactions with amlodipine oral tablet. Before taking this drug, you may want to discuss possible interactions with your doctor and pharmacist.
Things to consider include:
- Whether you drink alcohol or use cannabis.
- Other medications you take, as well as any vitamins, supplements, and herbs. Your doctor or pharmacist can help you fill out a medication list.
- What to do if your doctor prescribes a new drug while taking amlodipine oral tablet.
Taking amlodipine exactly as prescribed can also help prevent interactions.
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Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.