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Amlodipine oral tablet interactions: A detailed guide

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Amlodipine oral tablet is prescribed to treat certain heart problems and high blood pressure. This drug may interact with other medications and some supplements. Specifically, it can interact with nonsteroidal anti-inflammatory drugs and certain statins.
Medically reviewed by Victor Nguyen, PharmD, MBA
Updated on August 10, 2023

This article describes possible interactions with amlodipine oral tablet. Interactions can cause a drug to have a different effect on the body than expected. Interactions can occur due to medications, alcohol, or certain health conditions.

To find coupon options for amlodipine and to learn more about the drug, including its uses, see this article.

Other drugs and amlodipine

Before taking amlodipine oral tablet, tell your doctor and pharmacist about any prescription, over-the-counter, or other drugs you take. Doing so may help prevent possible interactions. If you’re concerned about possible interactions, talk with your doctor or pharmacist. They can tell you what should not be taken with amlodipine.

Drugs that may interact with amlodipine oral tablet are listed below. This article doesn’t include all drugs that may interact with amlodipine.

Drugs that may interact with amlodipine oral tablet include:

Questions about amlodipine and interactions

Here you’ll find answers to some common questions about amlodipine and possible interactions.

Do bananas and amlodipine interact?

No, amlodipine oral tablet isn’t known to interact with bananas.

Amlodipine oral tablet is prescribed to treat certain heart problems and high blood pressure. Certain other medications used for these conditions may interact with foods that are high in potassium, such as bananas. But amlodipine doesn’t have this interaction.

If you have other questions about amlodipine and certain foods, talk with your doctor or pharmacist.

What painkillers can I take with amlodipine?

Your doctor or pharmacist can recommend which pain relievers are safe to take with amlodipine oral tablet. For example, they may advise you to take acetaminophen (Tylenol) for pain relief during amlodipine treatment. This drug isn’t known to interact with amlodipine.

However, other drugs used to relieve pain are known to interact with amlodipine oral tablet. Your doctor or pharmacist will likely advise you to avoid these drugs while taking amlodipine, including:

Talk with your doctor or pharmacist before taking any pain medications during treatment with amlodipine oral tablet.

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Other interactions and amlodipine

Interactions can occur with supplements, foods, vaccines, and some lab tests. Below you can learn whether amlodipine oral tablet has these interactions.

The information below doesn’t include all other possible interactions with amlodipine.

Amlodipine and supplements

Before taking amlodipine oral tablet, tell your doctor and pharmacist about any supplements, herbs, and vitamins you take. Doing so may help you avoid possible interactions.

Amlodipine oral tablet may interact with fish oil supplements. Some people take these supplements to lower blood pressure and for other uses. Amlodipine also lowers blood pressure. So, taking amlodipine and fish oil supplements together may lead to very low blood pressure.  

Because of this, you should talk with your doctor or pharmacist before taking fish oil and other supplements with amlodipine oral tablet. They can tell you whether it’s safe to take them together.

If you have questions about interactions that may affect you, talk with your doctor or pharmacist.

Amlodipine interactions with herbs

Amlodipine oral tablet may interact with St. John’s wort. Some people use this herb for depression and other conditions.

Taking amlodipine and St. John’s wort may lead to a low level of amlodipine in your body. This could cause amlodipine to be less effective for your condition.

Because of this, you should talk with your doctor or pharmacist before taking St. John’s wort or any other herbs with amlodipine oral tablet. They can tell you whether it’s safe to take them together.

Amlodipine interactions with vitamins

Amlodipine oral tablet isn’t known to interact with any vitamins. But this doesn’t mean interactions with vitamins can’t happen or won’t be identified later.

Because of this, you should ask your doctor or pharmacist before taking any of these products during treatment with amlodipine oral tablet. They can tell you whether certain vitamins should not be taken with amlodipine.

Amlodipine and food

Amlodipine oral tablet isn’t known to interact with foods. But this doesn’t mean interactions with foods can’t happen or won’t be identified later.

Because of this, you should ask your doctor or pharmacist which foods to avoid during treatment with amlodipine oral tablet.

Amlodipine and vaccines

Amlodipine oral tablet isn’t known to interact with any vaccines. But this doesn’t mean interactions with vaccines can’t happen or won’t be identified later.

Because of this, you should talk with your doctor or pharmacist before receiving any vaccines during treatment with amlodipine oral tablet.

Amlodipine and lab tests

Amlodipine oral tablet isn’t known to interact with lab tests. But this doesn’t mean interactions with lab tests can’t happen or won’t be identified later.

Because of this, you should talk with your doctor or pharmacist before having any tests during treatment with amlodipine oral tablet.

Amlodipine and cannabis or CBD

Amlodipine oral tablet isn’t known to interact with cannabis (commonly called marijuana) or cannabis products such as cannabidiol (CBD). But this doesn’t mean interactions can’t happen or won’t be identified later.

As with any drug or supplement, tell your doctor before using cannabis with amlodipine oral tablet.

Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees.

When to avoid amlodipine

Certain health conditions or other factors could increase some risks with amlodipine oral tablet. Because of this, doctors may not prescribe amlodipine in these cases. These health conditions or other factors are called contraindications.

Here’s a contraindication for amlodipine oral tablet:

  • Past allergic reaction to amlodipine. If you’ve had an allergic reaction to amlodipine oral tablet in the past, taking amlodipine may cause another allergic reaction.

Before starting treatment with amlodipine, tell your doctor if you’ve had an allergic reaction to amlodipine oral tablet. They can recommend whether you should take it.

Alcohol and amlodipine

Amlodipine oral tablet is not known to interact with alcohol.

If you drink alcohol, talk with your doctor about whether it’s safe to consume it during your treatment
with amlodipine oral tablet.

Health factors and amlodipine

Certain medical conditions or other health factors may increase the risk of interactions with amlodipine oral tablet. Before taking amlodipine, tell your doctor about your health history. They’ll determine whether amlodipine is right for you.

Here’s a list of health conditions or other factors that might interact with amlodipine oral tablet:

Preventing amlodipine interactions

You may be able to help avoid certain interactions with amlodipine oral tablet. Before taking this drug, you may want to discuss possible interactions with your doctor and pharmacist.

Things to consider include:

  • Whether you drink alcohol or use cannabis.
  • Other medications you take, as well as any vitamins, supplements, and herbs. Your doctor or pharmacist can help you fill out a medication list.
  • What to do if your doctor prescribes a new drug during your amlodipine oral tablet treatment.

Taking amlodipine exactly as prescribed can also help prevent interactions.

What to ask your doctor

If you have questions about amlodipine and possible interactions, talk with your doctor.

Questions you may want to ask your doctor include:

  • Does my risk of interactions depend on my dosage of amlodipine oral tablet?
  • Do other drugs that could treat my condition have similar interactions?
  • Could I still take amlodipine oral tablet if it interacts with a health condition I have?

Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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