Provayblue

Methylene Blue

(METH i leen bloo)

ProvayBlue

A severe and sometimes deadly problem called serotonin syndrome may happen. The risk may be greater if you also take certain other drugs. Call your doctor right away if you have agitation; change in balance; confusion; hallucinations; fever; fast or abnormal heartbeat; flushing; muscle twitching or stiffness; seizures; shivering or shaking; sweating a lot; severe diarrhea, upset stomach, or throwing up; or very bad headache. Talk with your doctor if you take any drugs (prescription or OTC, natural products, vitamins) that must not be taken with this drug, like certain drugs that are used for low mood (depression), other mental or mood problems, or migraine headaches. There are many drugs that must not be taken with this drug or for some time before this drug is started. Ask your doctor or pharmacist.

It is used to treat methemoglobinemia. It may be given to you for other reasons. Talk with the doctor.

If you have an allergy to methylene blue or any other part of this drug. If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had. If you have G6PD deficiency. If you are pregnant or may be pregnant. Do not take this drug if you are pregnant. If you are breast-feeding. Do not breast-feed while you take this drug or within 8 days after your last dose. If this drug is not being given into a vein. This drug must not be given into the spine. Talk with the doctor. This is not a list of all drugs or health problems that interact with this drug. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists. Have blood work checked as you have been told by the doctor. Talk with the doctor. Check blood pressure and heart rate as the doctor has told you. You may need to have an ECG checked before starting this drug and while taking it. Talk with your doctor. This drug may affect certain lab tests. Tell all of your health care providers and lab workers that you take this drug. Avoid driving and doing other tasks or actions that call for you to be alert until you see how this drug affects you. You may get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen and wear clothing and eyewear that protects you from the sun. This drug may cause harm to the unborn baby if you take it while you are pregnant. If you are pregnant or you get pregnant while taking this drug, call your doctor right away.

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Dizziness or passing out. Feeling confused. Headache. Upset stomach or throwing up. Sweating a lot. A heartbeat that does not feel normal. Shortness of breath. Chest pain. Fever. Feeling very tired or weak. Pale skin. A burning, numbness, or tingling feeling that is not normal.

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Diarrhea. Change in color of urine or stool to blue or green. Belly pain. Change in color of skin to blue-green. Pain in arms or legs. Feeling hot or cold. Change in taste. Muscle pain. Pain where the shot was given. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely. It is given as a shot into a vein.

Call your doctor to find out what to do.

If you need to store this drug at home, talk with your doctor, nurse, or pharmacist about how to store it.

If your symptoms or health problems do not get better or if they become worse, call your doctor. Do not share your drugs with others and do not take anyone else's drugs. Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area. Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider. If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.