Interactions and warnings for ramipril

Below you’ll find information about ramipril’s possible interactions and warnings.

Interactions of ramipril

Certain things may affect how a drug works. These include getting vaccines, consuming alcohol or certain foods, or taking the drug with other medications. This effect is called a drug interaction.

Before you take ramipril, ask your doctor to check for possible interactions. Be sure to tell them about any of the following you take or use:

prescription or over-the-counter drugs
vitamins, herbs, or supplements

To learn about drug-condition interactions, see the “Warnings for ramipril” section below.

Warnings for ramipril

Some people should not take ramipril, and others should take it cautiously.

Boxed warning: Risk of fetal harm

Ramipril has a boxed warning about the risk of fetal harm. Boxed warnings are the most serious warnings from the Food and Drug Administration (FDA).

For details, see the “Pregnancy or breastfeeding and ramipril” section below.

Other warnings

Ramipril could cause harm to people with certain health conditions. This effect is called a drug-condition interaction. Other factors can also affect whether ramipril is a safe option for you.

Ask your doctor about specific warnings for ramipril, and be sure to tell your doctor about your:

current health, including any allergies to medications
past health conditions or surgeries

Allergic reaction

Ramipril can cause an allergic reaction in some people. Severe allergic reactions are rare but possible.

If you’ve had an allergic reaction to ramipril or any of its ingredients, your doctor will likely not prescribe ramipril. They can tell you about medications that are safer options for you.

A mild allergic reaction may cause the following symptoms:

skin rash
itchiness
flushing (temporary warmth, redness, or deepening of skin color)

A severe allergic reaction may cause the following symptoms:

swelling under your skin, usually in your hands, feet, eyelids, or lips
swelling of your mouth, throat, or tongue, which can cause breathing problems

If you have an allergic reaction to ramipril, call your doctor right away. If you have severe symptoms, call 911 or a local emergency number.

Overdose of ramipril

You should not take more ramipril than your doctor prescribes. For some drugs, doing so may lead to harmful effects or overdose.

If you think you’ve taken too much ramipril, call your doctor or pharmacist right away. Or you could call 800-222-1222 to speak with someone at America’s Poison Centers. You can also use its online resource. If you have concerning symptoms, call 911 or a local emergency number immediately. You can also go to the closest emergency room.

Pregnancy or breastfeeding and ramipril

Information about ramipril and pregnancy and breastfeeding is described below.

Ramipril and pregnancy

Ramipril should not be taken during pregnancy. If you’re planning a pregnancy or can become pregnant, talk with your doctor before taking this medication. Your doctor may suggest birth control options to use during treatment with ramipril.

Boxed warning: Risk of fetal harm

Ramipril has a boxed warning about the risk of fetal harm. Boxed warnings are the most serious warnings from FDA.

Ramipril and similar drugs may increase the chances of fetal harm and even death if taken during the second and third trimester of pregnancy.

If you become pregnant during ramipril treatment, stop taking the drug and contact your doctor immediately.

To learn more, talk with your doctor or pharmacist.

Ramipril and breastfeeding

Ramipril should not be taken while breastfeeding. If you’re currently breastfeeding or planning to do so, talk with your doctor before using this medication. Your doctor can recommend other ways to feed your child during treatment with ramipril.