Permethrin cream is a generic medication that doctors use to treat scabies. It’s only available with a prescription from a doctor or licensed healthcare professional.
If you have a prescription for permethrin cream, you’ll be able to get it at most pharmacy chains in the United States, such as CVS, Walgreens, RiteAid, and local pharmacies.
You can also buy permethrin cream at an online pharmacy if you have a valid prescription. If you already have a prescription and need a refill, an online health service may be a convenient option.

Can you buy permethrin cream over the counter?
No, you can’t buy permethrin cream over the counter. You’ll need to consult with a doctor or licensed healthcare professional to get a prescription for this medication.
Permethrin cream, like many drugs, can have side effects and may not be safe for everyone. That’s why it’s important for a healthcare professional to review your specific symptoms, overall health, and other medications that you may be taking. This information can help them decide about the type of treatment plan that may be most effective for you, with the lowest risk of side effects or negative interactions.
Although you can’t buy permethrin cream over the counter, permethrin lotion (Nix) is an over-the-counter (OTC) product that you can get at most pharmacies or big-box stores. However, it’s important to note that these two products are used for different purposes. You can’t use one in place of the other.
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What is the difference between permethrin cream and permethrin lotion?
Permethrin cream is a generic medication approved by the Food and Drug Administration (FDA) to get rid of scabies in adults and children ages 2 months of age and older. Permethrin cream is available by prescription only. It’s usually prescribed as a one-time treatment that you apply all over your skin from the neck down.
Permethrin lotion, on the other hand, is a generic medication that’s used to treat head lice. It’s available as the brand-name drug Nix. You can buy permethrin lotion over the counter at most big-box stores or pharmacies, or online.
What is scabies?
Scabies is a skin infestation that’s caused by tiny parasitic mites. These mites can burrow into your skin to lay eggs, causing an itchy skin rash. Symptoms of scabies can include:
- an intensely itchy skin rash
- itching that gets worse at night
- a rash that looks like tiny bites or bumps under the skin
- squiggly-looking lines or burrows on the skin
Scabies is usually treated with a topical prescription medication like permethrin cream. Other treatment options may include Crotan (crotamiton) lotion or oral ivermectin.
What are head lice?
Head lice are tiny, wingless bugs that can infest your hair and lay eggs on or near your scalp. Head lice infestations are especially common among preschool- and elementary school-age children and their families.
Head lice don’t always cause symptoms, but when symptoms are present, they may include:
- an itchy scalp
- a crawling sensation on the scalp
- sores on the scalp can contract infection due to scratching
Head lice can be treated with both OTC and prescription medications. If an OTC product like permethrin lotion doesn’t work, you may want to get a prescription medication.
You can consult with your doctor or use an online health service, like the one offered by Optum Perks, to get a prescription medication for head lice.
Can you buy permethrin cream online?
You can’t buy permethrin cream online without a prescription. But, you can buy it at an online pharmacy if you have a prescription. Or, you may be able to get a refill through an online health service. This may be especially helpful if you need a refill as soon as possible or after hours when your doctor isn’t available.
If you have any questions about how to get a prescription for permethrin cream or where to buy it, talk with your doctor or pharmacist.
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Get free cardHow much does permethrin cream cost?
The amount you’ll pay for permethrin cream depends on several factors such as:
- whether you have insurance
- the type of insurance plan you have
- the pharmacy you use
- your treatment plan
Typically, the cost of permethrin cream with insurance is lower than the cost of this drug without insurance. Keep in mind that you may have an insurance copay or a deductible that can affect the cost of permethrin cream.
If you don’t have insurance, you may be able to save money on the cost of permethrin cream by using a drug coupon, or assistance programs. Also, talk with your doctor or pharmacist about resources that may help lower the cost of permethrin cream.
Summary
Permethrin cream is a generic medication that’s used to treat scabies and can be bought at most pharmacies. You need a prescription from a doctor or healthcare professional for this drug. You can’t buy it over the counter. But, if you already have a prescription and need a refill, you can look into using an online health service.
Permethrin lotion is a generic medication that’s available as the brand-name drug Nix. It’s used to treat head lice and is available over the counter. However, if OTC products don’t get rid of head lice, you can consult with your doctor or use an online health service to get a prescription medication.