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Trulance dosage: A detailed guide

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Doctors prescribe Trulance oral tablet for treating constipation due to certain causes in adults. You take it by mouth once per day.
Medically reviewed by Bryson Russell, PharmD, MHSA, MSc
Updated on

This article describes Trulance oral tablet’s dosage and strength and gives details on how to take it. You’ll also find information on cost savings and coupon options for Trulance. If you want to know more about Trulance oral tablet, see this overview article. It covers details about the drug’s uses and side effects, ways to save on cost, and more.

Trulance is a brand-name medication that comes as a tablet which you swallow. It isn’t available in a generic version. This article describes dosages of Trulance.

Trulance oral tablet has a boxed warning for the risk of serious dehydration in children. A boxed warning is the most serious warning from the Food and Drug Administration (FDA). For details, see the end of this article.

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Form and strength of Trulance

Trulance oral tablet comes as follows:

  • Form: oral tablet, which you’ll take by swallowing
  • Strength: 3 milligrams (mg)

Dosage of Trulance

This article describes the recommended dosage for Trulance oral tablet. The drugmaker provides these dosages.

If your doctor prescribes this medication, you should follow the dosage they prescribe. Your doctor will determine the dosage that best meets your needs. Do not change your dosage of Trulance oral tablet without your doctor’s recommendation.

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Usual recommended dosage of Trulance in adults

Trulance is prescribed to adults to treat:

Dosage for constipation (CIC and IBS-C)

  • Dose: 3 mg
  • Frequency: once per day

Frequently asked questions

Below are answers to some commonly asked questions about Trulance oral tablet and its dosage.

What is the maximum dosage of Trulance?

The maximum dosage of Trulance recommended is 3 mg taken once per day. This is also the recommended starting and maintenance dosage of Trulance.

So if taking Trulance 3 mg per day isn’t working for your symptoms, talk with your doctor. Since Trulance doesn’t have other recommended dosages, they may suggest exploring other treatments for your constipation instead.

Is 6 mg a recommended dosage of Trulance? Can I take Trulance twice a day?

No, 6 mg is not a recommended dosage of Trulance. And taking Trulance twice a day isn’t a recommended dosage, either.

Let your doctor know if your constipation symptoms don’t ease or get worse while taking Trulance. They can recommend whether you should stop taking Trulance and explore other treatments for your symptoms instead.

How does the dosage of Trulance compare vs. Linzess?

Trulance and Linzess are both approved to treat the following conditions in adults:

For treating CIC or IBS-C, Trulance and Linzess are taken once daily. But the actual dose differs, since Trulance and Linzess have different active ingredients (what makes a drug work).

With Trulance, the dosage is the same whether you’re taking it to treat CIC or IBS-C. But Linzess has different recommended dosages depending on the condition it’s prescribed to treat. You can read this article to learn more about Linzess dosages for treating CIC and IBS-C.

Linzess is also approved to treat functional constipation (FC) in children ages 6 to 17 years. Trulance isn’t approved for this or any use in people under the age of 18 years. To learn more about why Trulance isn’t recommended for use in children, see the “Boxed warning for Trulance” section at the end of this article.

Talk with your doctor or pharmacist if you’d like to learn more about how Trulance and Linzess compare.

Trulance coupon

Visit this page to access Optum Perks coupons and get price estimates for Trulance when you use the coupons. These coupons can provide significant savings on your prescription costs. 

Note: Optum Perks coupons can’t be used with insurance copays or benefits.

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Overdose of Trulance

It’s important that you do not take more Trulance oral tablet than your doctor prescribes. Doing so can lead to harmful effects.

What to do if you take too much Trulance

If you think you’ve used too much Trulance, call your doctor or pharmacist right away. Or you could call 800-222-1222 to speak with someone at America’s Poison Centers. You can also use its online resource. If you have severe symptoms, call 911 or a local emergency number immediately. You can also go to the closest emergency room.

Boxed warning for Trulance

Trulance has a boxed warning for the risk of serious dehydration in children. A boxed warning is the most serious warning from the FDA.

Based on animal studies, Trulance could cause severe diarrhea and serious dehydration. Symptoms of dehydration include dry mouth, headache, and disorientation. Animal studies don’t always predict a drug’s effects when used by people.

But due to this risk, Trulance should not be prescribed for use in in children under 6 years of age. It’s also recommended that anyone under age 18 years avoids using Trulance. It isn’t known whether Trulance is safe or effective for treating any condition in people under 18 years of age. Trulance is only approved for use in adults.

Talk with your doctor to learn more.

Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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