Sumatriptan oral tablet is a generic version of the brand-name drug Imitrex. Sumatriptan also comes as a solution for injection under the skin, a nasal spray, and a nasal powder. But this article doesn’t describe those forms. To learn more about these forms, talk with your doctor.
This article describes sumatriptan oral tablet’s dosage and strengths and gives details on how to take it. You’ll also find information on cost savings and coupon options for sumatriptan. If you want to know more about sumatriptan oral tablet, see this overview article. It covers details about the drug’s uses, side effects, and more.
Form and strengths of sumatriptan
Sumatriptan oral tablet comes as follows:
- Form: tablet that you swallow
- Strengths: 25 milligrams (mg), 50 mg, 100 mg
Dosage of sumatriptan
This article describes the recommended dosage for sumatriptan oral tablet. These are provided by the drugmaker.
If your doctor prescribes this medication, you should follow the dosage they prescribe. Your doctor will determine the dosage that best meets your needs. Do not change your dosage of sumatriptan oral tablet without your doctor’s recommendation.
Usual recommended dosage of sumatriptan in adults
Usually, doctors start by prescribing a low dosage of sumatriptan oral tablet. Then, they may adjust it over time until the right dosage is reached. Ultimately, your doctor will prescribe the smallest dosage of sumatriptan oral tablet that relieves your symptoms.
Sumatriptan oral tablet is prescribed for treating migraine with or without aura in adults. You take it as needed, as soon as you feel symptoms of a migraine episode, such as a headache.
The recommended dosage of sumatriptan oral tablet is as follows:
- Starting dosage: 25 milligrams (mg), 50 mg, or 100 mg, taken at the start of a migraine episode
- Maximum dosage: 200 mg per day (24 hours)
Note: For migraine not responding to your first dose, your doctor may recommend a second dose. For example, if your doctor prescribes 25 mg, they’ll recommend another 25-mg dose. You’ll need to wait at least 2 hours after the first dose before taking the second. It’s unknown whether it’s safe to take sumatriptan to treat an average of more than four migraine episodes in a 30-day period.
Dosage adjustments for sumatriptan
Your doctor will prescribe a dosage of sumatriptan oral tablet based on several factors, including:
- your migraine symptoms and severity
- other health conditions you may have
If you have liver problems, your doctor will lower your maximum daily dose of sumatriptan. For severe liver disease, such as liver failure, doctors typically won’t prescribe the drug. If you have questions about dosage adjustments, talk with your doctor.
Frequently asked questions
Below are answers to some commonly asked questions about sumatriptan oral tablet and its dosage.
Is the dosage of sumatriptan oral tablet similar to the dosage of the injection form of the drug?
No, the sumatriptan oral tablet dosage is different from the dosage of the injection form of the drug. Sumatriptan injection comes as a liquid solution that you inject under your skin.
Both forms of the drug are taken at the first sign of a migraine episode. However, the dosage of sumatriptan oral tablet is higher than that of sumatriptan injection. This is because your body absorbs more sumatriptan after injecting it under your skin than after taking the oral tablet. Absorbing more of the drug means you need less medication to get the same effect.
To learn about sumatriptan oral tablet dosages, see the “Dosage of sumatriptan” section above. If you’re interested in sumatriptan injection, talk with your doctor for more information.
What is the maximum dosage of sumatriptan per week?
There’s no recommended maximum dosage of sumatriptan per week. Sumatriptan oral tablet is taken as needed for migraine relief. The maximum dosage per day is 200 milligrams (mg).
Taking migraine medications, including sumatriptan, too often can cause medication overuse headache (formerly “rebound headache”). Due to this side effect, doctors limit the use of sumatriptan oral tablet to no more than four migraine episodes per month. To learn more about sumatriptan oral tablet side effects, see this article.
If your sumatriptan oral tablet dosage isn’t relieving your symptoms, talk with your doctor. They’ll determine whether to adjust your dosage or treatment plan. If you experience frequent migraine episodes, your doctor may recommend a different treatment option.
Is sumatriptan taken long term?
No, doctors don’t typically prescribe sumatriptan oral tablet as a long-term treatment. Instead, it’s usually recommended for use as needed to treat a migraine episode.
Typically, doctors recommend limiting sumatriptan use to up to four migraine episodes a month. Your doctor will tell you how often you can take sumatriptan oral tablet.
Talk with your doctor if you’re interested in long-term treatment for migraine. They’ll be able to recommend a treatment option that’s right for you.
How sumatriptan is taken
Sumatriptan oral tablet is taken by mouth. You’ll take your dose as needed for a migraine episode. If this dose doesn’t relieve your symptoms, follow your doctor’s instructions for a second dose. Be sure to wait at least 2 hours after the first dose before taking the second. It’s important that you do not take more than 200 milligrams (mg) of sumatriptan oral tablet in a 24-hour period.
If it’s hard for you to swallow tablets, view this article. It provides suggestions on how to swallow medications that come in pill form.
Also, be sure to talk with your doctor or pharmacist if you’re having difficulty taking your medication. They can offer recommendations about taking it. They may also suggest a different form of sumatriptan, such as the nasal spray.

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Overdose of sumatriptan
It’s important that you do not take more sumatriptan oral tablet than your doctor prescribes. Doing so can lead to harmful effects. To learn about sumatriptan oral tablet side effects, see this article.
What to do if you take too much sumatriptan
If you think you’ve taken too much sumatriptan, call your doctor or pharmacist right away. Or you could call 800-222-1222 to speak with someone at America’s Poison Centers. You can also use its online resource. If you have severe symptoms, call 911 or a local emergency number immediately. You can also go to the closest emergency room.
What to ask your doctor
This article describes the usual recommended dosages for sumatriptan oral tablet. If your doctor prescribes this medication, they’ll determine the dosage that’s best for you.
Do not change your dosage of sumatriptan oral tablet without your doctor’s recommendation. You should take sumatriptan oral tablet exactly as your doctor prescribes it. Let your doctor know if you have concerns or questions about your treatment plan.
Here’s a list of some possible questions you may want to ask your doctor:
- Can you prescribe a higher dosage of sumatriptan oral tablet after my first dose?
- Will you change my dosage of sumatriptan oral tablet if I take other medication for migraine?
- Will I need a new sumatriptan oral tablet prescription if you change my dosage?
Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.