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Oxycodone oral tablet dosage: A detailed guide

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Form and strengthsDosageFAQsHow it’s takenCouponOverdoseAsk your doctorBoxed warnings
Oxycodone oral tablet is prescribed for severe pain in adults. It’s taken by mouth once every 4 to 6 hours as needed.
Medically reviewed by Elizabeth Scheffel, PharmD
Updated on

Oxycodone oral tablet is a generic version of the brand-name drug Roxicodone. Oxycodone also comes in another oral form called Oxaydo, which has features to prevent misuse. But this form isn’t described in this article. To learn more about this form, talk with your doctor.

This article describes oxycodone oral tablet’s dosage, its strengths, and details on how to take it. You’ll also find information on cost savings and coupon options for oxycodone.

If you want to know more about oxycodone oral tablet, see this overview article. It covers details about the drug’s uses, side effects, ways to save on cost, and more.

Boxed warnings

This drug has boxed warnings about certain risks. Boxed warnings are serious warnings from the Food and Drug Administration (FDA). The warnings are for:

  • risk of misuse and addiction
  • risk of respiratory depression
  • risk of overdose with accidental ingestion
  • risk of neonatal opioid withdrawal syndrome
  • risk if taken together with certain drugs

To learn more, see “Dosage adjustments for oxycodone” in the “Dosage of oxycodone” section below. Additionally, talk with your doctor and see the end of this article for more information about these warnings.

Form and strengths of oxycodone

Oxycodone oral tablet comes as follows:

  • Form: tablet that you swallow
  • Strengths:
    • 5 milligrams (mg)
    • 10 mg
    • 15 mg
    • 20 mg
    • 30 mg

Dosage of oxycodone

This article describes the recommended dosage* for oxycodone oral tablet.

If your doctor prescribes this medication, you should take the dosage they prescribe. Your doctor will determine the dosage that best meets your needs. Do not change your dosage of oxycodone oral tablet without your doctor’s recommendation.

* The drugmaker provides this recommended dosage.

Usual recommended dosage of oxycodone

Usually, doctors start by prescribing a dosage that depends on your level of pain. They may adjust the hours between doses or the strength to meet your pain relief needs. Ultimately, your doctor will prescribe the smallest dosage of oxycodone oral tablet that gives the desired outcome.

The usual recommended dosage of oxycodone oral tablet is as follows:

  • Dose: 5 milligrams (mg) to 15 mg
  • Frequency: once every 4 to 6 hours as needed for pain

Dosage adjustments for oxycodone

Your doctor will prescribe a dosage of oxycodone oral tablet based on several factors, including:

  • how severe your pain is
  • your age and weight
  • other health conditions you may have
  • other medications you take
  • whether you’ve taken an opioid in the past and what kind
  • whether your pain is short term or long term
  • how your body responds to the drug
  • your risk of misuse or addiction

To learn more about misuse and addiction, see “Boxed warnings for oxycodone” at the end of this article.

Missed dose of oxycodone

Talk with your doctor or pharmacist right away if you realize you forgot to take a dose of oxycodone oral tablet. They may advise you to take the missed dose. Or they may advise you to skip it and take your next dose as scheduled.

For tips on how to plan your doses of oxycodone oral tablet and avoid missing a dose, read this article. You could also try:

  • downloading a reminder app on your phone
  • setting an alarm
  • putting a note where you’ll see it, such as on your calendar, bathroom mirror, or bedside table

Frequently asked questions

Below are answers to some commonly asked questions about oxycodone oral tablet and its dosage.

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Will my oxycodone dose be calculated based on weight?

No, it won’t. The dosage for oxycodone oral tablet isn’t based on weight.

The drugmaker does recommend that doctors consider your age and weight when prescribing oxycodone. But if you’re otherwise healthy, your weight isn’t the main factor in determining dosage. Doctors usually start your treatment by prescribing a dosage for your level of pain.

If you have questions or concerns about your weight and dosage, talk with your doctor or pharmacist.

How does the dosage of oxycodone compare with the dosage of hydrocodone?

Hydrocodone and oxycodone oral tablet are opioid drugs. Hydrocodone relieves severe pain and carries many of the same risks and warnings as oxycodone oral tablet. This includes the risk of misuse and addiction. Misuse is taking a drug in a way that’s different from how a doctor prescribes it. Addiction is feeling unable to stop taking a drug even though it may be causing harm. But hydrocodone comes in different strengths and has different dosing.

If you’d like to learn more about hydrocodone, talk with your doctor. They can tell you the best option for managing your pain.

Is oxycodone taken long term?

It depends. If your pain is short term, your doctor will prescribe oxycodone oral tablet for a limited time. But if the pain is long lasting, doctors may prescribe oxycodone oral tablet as a long-term treatment.

If you have questions about how long you should take oxycodone oral tablet, talk with your doctor.

Is there a risk of misuse with oxycodone?

Yes, oxycodone has a risk of misuse. In fact, oxycodone oral tablet has a boxed warning for the risk of misuse and addiction. Boxed warnings are serious warnings from the Food and Drug Administration (FDA).

Misuse means taking a drug in a way that’s different from how a doctor prescribes it. People might misuse oxycodone oral tablet to get a “high” feeling from the drug.

Misusing oxycodone oral tablet in this way can lead to addiction and a fatal overdose. Addiction means feeling unable to stop taking a drug even though it may be causing harm.

You should take oxycodone oral tablet exactly as directed by your doctor. This means taking the tablet by mouth and waiting the prescribed number of hours between doses. If you feel like oxycodone oral tablet isn’t managing your pain, let your doctor know. Do not change how often you take the drug on your own.

Discuss any concerns you have about taking oxycodone oral tablet with your doctor.

How oxycodone is taken

Oxycodone oral tablet is swallowed. You’ll likely take it once every 4 to 6 hours as needed for pain. You can take it with food or without it.

If it’s hard for you to swallow tablets, view this article. It provides suggestions on how to swallow medications that come in pill form. Oxycodone oral tablets can also be chewed, split, or crushed to make taking them easier.

Be sure to talk with your doctor or pharmacist if you’re having difficulty taking your medication. They can offer recommendations about taking it.

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Overdose of oxycodone

It’s important that you do not take more oxycodone oral tablet than your doctor prescribes. Doing so can lead to serious side effects.

Symptoms of oxycodone overdose

Symptoms of an overdose can include:

  • cold and clammy skin
  • extreme drowsiness or sleepiness
  • limp muscles
  • loss of consciousness, which can lead to coma and death in extreme cases
  • slow or shallow breathing
  • very small eye pupils

What to do if you take too much oxycodone

If you think you’ve taken too much oxycodone, call your doctor or pharmacist right away. Or you could call 800-222-1222 to speak with someone at America’s Poison Centers. You can also use its online resource. If you have severe symptoms, call 911 or a local emergency number immediately. You can also go to the closest emergency room.

What to ask your doctor

This article describes the usual recommended dosage for oxycodone oral tablet. If your doctor prescribes this medication, they’ll determine the dosage that’s best for you.

Do not change your dosage of oxycodone oral tablet without your doctor’s recommendation. You should take oxycodone oral tablet exactly as your doctor prescribes it. Let your doctor know if you have concerns or questions about your treatment plan.

Here’s a list of some possible questions you may want to ask your doctor:

  • Is there a liquid form of oxycodone I can take instead of the tablets?
  • How long do you recommend I take oxycodone oral tablet?
  • Would a higher dose of oxycodone oral tablet increase my risk of misuse and addiction?
  • Does my dosage of oxycodone oral tablet need to be adjusted for the other medications I take?

Boxed warnings for oxycodone

This drug has boxed warnings about certain risks. Boxed warnings are serious warnings from the Food and Drug Administration (FDA).

Risk of misuse and addiction. Taking oxycodone oral tablet exposes you to a risk of addiction and misuse. Misuse is taking a drug in a way that’s different from how a doctor prescribes it. Addiction is feeling unable to stop taking a drug, even though it may be causing harm. Due to this risk, doctors will assess your treatment routinely.

Risk of respiratory depression. Taking oxycodone oral tablet can lead to respiratory depression. This serious condition occurs when breathing becomes very slow or shallow, and it can be fatal. Because of this risk, doctors typically won’t prescribe oxycodone if you take other medications that slow breathing. This includes benzodiazepines. If you drink alcohol, they’ll advise you to avoid it while taking oxycodone as it can slow your breathing.

Risk of overdose with accidental ingestion. Accidentally taking oxycodone oral tablet can lead to a fatal overdose. Children especially are at risk of a fatal overdose. Oxycodone is not approved for use in children. It’s important to store your medication in a safe place that can’t be easily accessed by others, especially children.

Risk of neonatal opioid withdrawal syndrome. Taking oxycodone oral tablet for an extended time during pregnancy can cause problems in a newborn. This includes withdrawal symptoms, which can be fatal. Withdrawal refers to side effects that occur when you stop taking a drug on which your body is dependent. Dependence is when your body needs the drug to feel like you usually do. Due to this risk, doctors typically won’t prescribe oxycodone during pregnancy unless the benefit outweighs the risk.

Risk if taken together with certain drugs. Taking oxycodone together with certain drugs can cause dangerous drug interactions. These include central nervous system (CNS) depressants that slow brain function. Oxycodone is a CNS depressant. Other CNS depressants include muscle relaxers, such as cyclobenzaprine and methocarbamol.

Other drugs include pain medications such as tramadol and benzodiazepines such as alprazolam.

The risk also includes drugs that affect certain liver enzymes. Examples include erythromycin, ketoconazole, ritonavir, rifampin, carbamazepine, and phenytoin. If you take any of these, your oxycodone dose may need to be adjusted.

Doctors will need to review your medication list periodically to assess possible drug interactions.

You’ll find other details in “Dosage adjustments for oxycodone” in the “Dosage of oxycodone” section above. You can also speak with your doctor to learn more about these warnings.

Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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