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Metoprolol tartrate oral tablet interactions: A detailed guide

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Metoprolol tartrate oral tablet is prescribed to treat certain heart problems. This drug may interact with other medications. Specifically, it can interact with fluoxetine and clonidine.
Medically reviewed by Dena Westphalen, PharmD
Updated on

This article describes possible interactions with metoprolol tartrate oral tablet. Interactions can cause a drug to have a different effect on the body than expected. Interactions can occur due to medications, alcohol, or certain health conditions.

To find coupon options for metoprolol tartrate and to learn more about the drug, including its uses, see this article.

Metoprolol tartrate comes as tablets that you’ll swallow. It’s also available as a solution that’s injected into your vein.

Other drugs and metoprolol tartrate 

Drugs that may interact with metoprolol tartrate oral tablet are listed below. This article doesn’t include all drugs that may interact with metoprolol tartrate.

Drugs that may interact with metoprolol tartrate oral tablet include:

  • monoamine oxidase inhibitors (MAOIs):
  • certain calcium channel blockers:
    • drug examples: diltiazem (Cardizem CD, others) and verapamil (Verelan)
    • what might happen: can increase the risk of slow heart rate as a side effect from metoprolol tartrate, diltiazem, or verapamil
  • certain heart rhythm drugs:
    • drug examples: quinidine and propafenone (Rythmol SR)
    • what might happen: can increase the severity and risk of side effects from metoprolol tartrate
  • other drugs that slow the heart rate:
    • drug examples: amiodarone (Pacerone), disopyramide (Norpace)
    • what might happen: can increase the risk of slow heart rate as a side effect from metoprolol tartrate or other drugs that slow heart rate
  • fluoxetine (Prozac):
    • what might happen: can increase the severity and risk of side effects from metoprolol tartrate
  • paroxetine (Paxil, Brisdelle):
    • what might happen: can increase the severity and risk of side effects from metoprolol tartrate
  • digoxin (Lanoxin):
    • what might happen: can increase the risk of slow heart rate as a side effect from metoprolol tartrate or digoxin
  • clonidine (Nexiclon XR, Catapres):
    • what might happen: can increase the risk of slow heart rate as a side effect from metoprolol tartrate or clonidine

When to avoid metoprolol tartrate

Certain health conditions or other factors could increase some risks with metoprolol tartrate oral tablet. Because of this, doctors may not prescribe metoprolol tartrate in these cases. These health conditions or other factors are called contraindications.

Here’s a list of contraindications for metoprolol tartrate oral tablet:

  • Severe bradycardia. If you have severe bradycardia (slow heart rate), taking metoprolol tartrate oral tablet may worsen your condition.
  • Heart block. If you have second– or third-degree heart block, taking metoprolol tartrate oral tablet may cause your condition to worsen.
  • Sick sinus syndrome. If you have sick sinus syndrome, taking metoprolol tartrate oral tablet may worsen your condition.
  • Decompensated heart failure. If you have decompensated heart failure, taking metoprolol tartrate oral tablet may cause your condition to worsen.
  • Past allergic reaction to metoprolol tartrate. If you’ve had an allergic reaction to metoprolol tartrate oral tablet in the past, taking it may cause the allergic reaction to reoccur.

Before starting treatment with metoprolol tartrate, tell your doctor if anything listed above relates to you. They can recommend whether you should take metoprolol tartrate.

Questions about metoprolol tartrate and interactions

Here you’ll find answers to some common questions about metoprolol tartrate and possible interactions.

What vitamins should I not take with metoprolol tartrate?

If you take metoprolol tartrate, you should check with your doctor before taking a multivitamin.

Multivitamins often contain potassium. Rarely, metoprolol tartrate can cause hyperkalemia (high level of potassium in the blood) as a side effect. If you take a multivitamin that’s high in potassium, the risk of this side effect may increase.

It’s often safe to take a multivitamin with metoprolol tartrate with your doctor’s recommendation. But if you’re taking metoprolol tartrate, your doctor may want to check the amount of potassium in the multivitamin and in your blood. This is to make sure that your potassium level is not too high.

Talk with your doctor to learn more about taking vitamins with metoprolol tartrate.

Can I eat bananas with metoprolol tartrate?

It depends. Bananas are rich in potassium. And rarely, metoprolol tartrate can cause a high level of potassium in the blood as a side effect.

One banana contains about 422 milligrams (mg) of potassium. The recommended daily value of potassium is around 3,500–4,700 mg. Unless you’re eating multiple bananas per day, eating bananas is unlikely to cause high blood potassium.

Talk with your doctor about whether you should follow a specific diet while taking metoprolol tartrate.

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Does metoprolol tartrate oral tablet have different interactions than metoprolol succinate extended-release oral tablet?

No, reported interactions with metoprolol tartrate oral tablet are the same as those reported with metoprolol succinate extended-release tablet. (Extended release means the drug is slowly released in your body over time.)

Metoprolol tartrate and metoprolol succinate are very similar drugs. Both medications are prescribed to treat angina pectoris (chest pain) and high blood pressure. But unlike metoprolol tartrate, metoprolol succinate is prescribed to treat heart failure, and metoprolol tartrate is prescribed to treat a heart attack that just occurred. Metoprolol succinate isn’t approved for this use.

Talk with your doctor or pharmacist if you’d like to know more about how metoprolol tartrate and metoprolol succinate compare.

Alcohol and metoprolol tartrate

Metoprolol tartrate oral tablet is known to interact with alcohol.

Taking metoprolol tartrate oral tablet and drinking alcohol may cause:

Metoprolol is a type of drug called a beta-blocker. There are risks associated with taking a beta-blocker and drinking alcohol. To learn more, refer to this article.

If you drink alcohol and have concerns about avoiding it during treatment with metoprolol tartrate oral tablet, talk with your doctor.

Other interactions and metoprolol tartrate

Interactions can occur with supplements, foods, vaccines, and some lab tests. Below you can learn whether metoprolol tartrate oral tablet has these interactions.

The information below doesn’t include all other possible interactions with metoprolol tartrate.

Metoprolol tartrate and supplements

Before taking metoprolol tartrate oral tablet, tell your doctor and pharmacist about any supplements, herbs, and vitamins you take. Doing so may help you avoid possible interactions.

If you have questions about interactions that may affect you, talk with your doctor or pharmacist.

Metoprolol tartrate interactions with herbs

Metoprolol tartrate oral tablet isn’t known to interact with any herbs. But this doesn’t mean interactions with herbs can’t happen or won’t be identified later.

Because of this, you should ask your doctor or pharmacist before taking any of these products during treatment with metoprolol tartrate oral tablet.

Metoprolol tartrate interactions with vitamins

Metoprolol tartrate oral tablet isn’t known to interact with any vitamins. But this doesn’t mean interactions with vitamins can’t happen or won’t be identified later.

Because of this, you should ask your doctor or pharmacist before taking any of these products during treatment with metoprolol tartrate oral tablet.

Metoprolol tartrate and food

Metoprolol tartrate oral tablet isn’t known to interact with foods. But this doesn’t mean interactions with foods can’t happen or won’t be identified later.

Because of this, talk with your doctor or pharmacist about what foods you should avoid during treatment with metoprolol tartrate oral tablet.

Metoprolol tartrate and vaccines

Metoprolol tartrate oral tablet isn’t known to interact with any vaccines. But this doesn’t mean interactions with vaccines can’t happen or won’t be identified later.

Because of this, you should talk with your doctor or pharmacist before receiving any vaccines during treatment with metoprolol tartrate oral tablet.

Metoprolol tartrate and lab tests

Metoprolol tartrate oral tablet isn’t known to interact with lab tests. But this doesn’t mean interactions with lab tests can’t happen or won’t be identified later.

Because of this, you should talk with your doctor or pharmacist before having any tests during treatment with metoprolol tartrate oral tablet.

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Metoprolol tartrate and cannabis or CBD

Metoprolol tartrate oral tablet isn’t known to interact with cannabis (commonly called marijuana) or cannabis products such as cannabidiol (CBD). But this doesn’t mean interactions can’t happen or won’t be identified later.

As with any drug or supplement, tell your doctor before using cannabis with metoprolol tartrate.

Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees.

Health factors and metoprolol tartrate

Certain medical conditions or other health factors may increase the risk of interactions with metoprolol tartrate oral tablet. Before taking metoprolol tartrate, tell your doctor about your health history. They’ll determine whether metoprolol tartrate is right for you.

Here’s a list of some health conditions or other factors that might interact with metoprolol tartrate oral tablet:

Preventing metoprolol tartrate interactions

You may be able to help avoid certain interactions with metoprolol tartrate oral tablet. Before taking this drug, you may want to discuss possible interactions with your doctor and pharmacist.

Things to consider include:

  • Whether you drink alcohol or use cannabis.
  • Other medications you take, as well as any vitamins, supplements, and herbs. Your doctor or pharmacist can help you fill out a medication list.
  • What to do if you’re prescribed a new drug during your metoprolol tartrate oral tablet treatment.

Taking metoprolol tartrate exactly as prescribed can also help prevent interactions.

What to ask your doctor

If you have questions about metoprolol tartrate and possible interactions, talk with your doctor.

Questions you may want to ask your doctor include:

  • If metoprolol tartrate interacts with one of my health conditions, will you prescribe a lower dose?
  • How do interactions of metoprolol tartrate compare with other treatments for my condition?
  • If I take metoprolol tartrate and have certain health conditions, will I be monitored more closely during treatment?
  • Does my metoprolol tartrate dosage affect my risk of interactions?

Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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