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Vivelle-dot dosage: A detailed guide

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Form and strengthsDosageCouponOverdoseBoxed warnings
Doctors prescribe Vivelle-dot skin patch for symptoms caused by menopause. You apply it to your skin twice per week.
Medically reviewed by Molly Becze, PharmD, BCPS
Updated on

This article describes Vivelle-dot skin patch’s dosages and strengths and gives details on how it’s used. You’ll also find information on cost savings and coupon options for Vivelle-dot. To learn more about Vivelle-dot, talk with your doctor.

Vivelle-dot is a brand-name medication that comes as a skin patch. It’s available in a generic version called estradiol. This article describes dosages of Vivelle-dot.

Vivelle-dot skin patch has a boxed warning. A boxed warning is the most serious warning from the Food and Drug Administration (FDA). For details, see the end of this article.

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Form and strengths of Vivelle-dot

Vivelle-dot skin patch comes as follows:

  • Form: Transdermal patch system, which you’ll apply to your skin. A transdermal patch system means the patch will release a certain amount of medication each day that it is on your skin.
  • Strengths: 0.025 milligrams(mg) per day (mg/day), 0.0375 mg/day, 0.05 mg/day, 0.075 mg/day, or 0.1 mg/day

Dosage of Vivelle-dot

This article describes the recommended dosages for Vivelle-dot skin patch. The drugmaker provides these dosages. In some cases, doctors may adjust your dosage from those shown below.

If your doctor prescribes this medication, you should follow the dosage they prescribe. Your doctor will determine the dosage that best meets your needs. Do not change your dosage of Vivelle-dot skin patch without your doctor’s recommendation.

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Usual recommended dosages of Vivelle-dot in adults

Usually, doctors start by prescribing a low dosage of Vivelle-dot skin patch. Then, they’ll adjust it over time until the right dosage is reached. Ultimately, your doctor will prescribe the smallest dosage of Vivelle-dot skin patch that gives the desired outcome.

Dosage for hot flashes caused by menopause and other conditions

Condition/PurposeRecommended doseFrequency
Severe hot flashes caused by menopause0.0375 mg/day patchTwice per week
Severe thinning of the vaginal and vulva skin caused by menopause0.0375 mg/day patchTwice per week
Low estrogen caused by ovary issuesDepends on lab valuesDepends on lab values
Prevention of osteoporosis after menopause0.025 mg/day patchTwice per week

In individuals who don’t have a uterus, Vivelle-dot will be given continuously, meaning there will be no breaks. In individuals who do have a uterus, Vivelle-dot will be given on a cyclic schedule that is determined by their doctor.

An example of a cyclic schedule would be using Vivelle-dot for 3 weeks, and then taking 1 week off the medication.

Vivelle-dot coupon

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Overdose of Vivelle-dot

It’s important that you do not use more Vivelle-dot skin patch than your doctor prescribes. Doing so can lead to harmful effects.

Symptoms of Vivelle-dot overdose

Symptoms of an overdose can include:

  • nausea and vomiting
  • breast tenderness
  • drowsiness

What to do if you use too much Vivelle-dot

If you think you’ve used too much Vivelle-dot, call your doctor or pharmacist right away. Or you could call 800-222-1222 to speak with someone at America’s Poison Centers. You can also use its online resource. If you have severe symptoms, call 911 or a local emergency number immediately. You can also go to the closest emergency room.

Boxed warnings for Vivelle-dot

Vivelle-dot has a boxed warning for the increased risk of endometrial cancer, heart issues, dementia, and breast cancer. A boxed warning is the most serious warning from the FDA.

Risk of endometrial cancer: ln individuals who have a uterus and use certain estrogens, endometrial cancer risk is increased.

Risk of blood clots and heart issues: Individuals who take medication that only contains an estrogen or that have an estrogen and a progesterone may be at an increased risk of certain issues such as deep vein thrombosis, pulmonary embolism, stroke, and heart attack.

Risk of dementia: Individuals who are 65 years of age and older and who take medication that only contains an estrogen or an estrogen plus a progesterone may be at an increased risk of developing dementia after menopause.

Risk of breast cancer: Individuals who take medication that contains an estrogen and a progesterone may have an increased risk of breast cancer.

Due to these risks, doctors may not prescribe Vivelle-dot if you have a uterus, are a certain age, or have certain details in your health history. You can also talk with your doctor to learn more.

Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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