This article describes possible interactions with Jardiance. Interactions can cause a drug to have a different effect on the body than expected. Interactions can occur due to medications, supplements, alcohol, or certain health conditions.
Jardiance comes as tablets that you swallow.
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Other drugs and Jardiance
The drugs in the list below may interact with Jardiance. This article doesn’t include all drugs that may interact with Jardiance.
Drug classes or drugs that may interact with Jardiance include:
- diuretics (water pills):
- drug examples: hydrochlorothiazide (Microzide), bumetanide (Bumex)
- what might happen: can increase the risk of side effects of Jardiance and the diuretic
- insulins:
- drug examples: insulin glargine (Lantus), insulin lispro (Humalog)
- what might happen: can increase the risk of side effects of Jardiance and the insulin
- certain diabetes drugs:
- beta-blockers:
- drug examples: metoprolol (Lopressor)
- what might happen: can hide symptoms of low blood sugar levels
- certain antipsychotics:
- drug examples: aripiprazole (Abilify), quetiapine (Seroquel)
- what might happen: can make Jardiance less effective
- certain antibiotics:
- drug examples: ciprofloxacin (Cipro), levofloxacin (Levaquin)
- what might happen: can increase the risk of side effects of Jardiance
- lithium (Lithobid):
- what might happen: can make lithium less effective
- fluoxetine (Prozac):
- what might happen: can increase the risk of side effects of Jardiance
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Get free cardWhen to avoid Jardiance
Certain health conditions or other factors could increase some risks with Jardiance. If you have any of these health conditions or other factors, your doctor may not prescribe Jardiance. These health conditions or other factors are called contraindications.
Here’s a list of contraindications for Jardiance:
- Past allergic reaction to Jardiance: If you’ve ever had an allergic reaction to Jardiance, taking it again may cause another allergic reaction.
Before you start taking Jardiance, talk with your doctor about the contraindications of Jardiance. They can recommend whether you should take it.
Alcohol and Jardiance
Jardiance is not known to interact with alcohol.
But drinking alcohol while taking Jardiance can increase your risk of certain side effects or make certain side effects worse. These include:
- more frequent urination
- dizziness
- ketoacidosis
- low blood sugar levels
If you drink alcohol, talk with your doctor about whether it’s safe to consume it while taking Jardiance.
Other interactions and Jardiance
Interactions can occur with supplements, foods, vaccines, and some lab tests. Below you can learn whether Jardiance has these interactions.
The information below doesn’t include all other possible interactions with Jardiance.
Jardiance and supplements
Before taking Jardiance, tell your doctor and pharmacist about any herbs, vitamins, and supplements you take. Doing so may help you avoid interactions.
If you have questions about interactions that may affect you, talk with your doctor or pharmacist.
Jardiance and herbs
Jardiance may interact with garlic supplements. Some people use this herb to help with high blood sugar levels, high cholesterol levels, and high blood pressure.
Taking Jardiance and garlic supplements may increase your risk of low blood sugar levels.
Because of this, ask your doctor or pharmacist before taking any of these products while taking Jardiance.
Jardiance and minerals
Jardiance may interact with chromium. Some people use this mineral to manage blood sugar levels.
Taking Jardiance and chromium supplements may increase your risk of low blood sugar levels.
Because of this, ask your doctor or pharmacist before taking chromium supplements while taking Jardiance.
Jardiance and food
Jardiance may interact with certain foods, including green tea.
Green tea can lower your blood sugar levels. Drinking green tea while taking Jardiance may increase your risk of low blood sugar levels.
Jardiance may also interact with a ketogenic diet. A ketogenic diet is high in fats and low in carbs. It works by changing the main source of energy in your body from carbs to fats. But following a ketogenic diet while taking Jardiance may increase your risk of ketoacidosis.
Because of this, talk with your doctor or pharmacist about what foods to avoid while taking Jardiance.
Jardiance and vaccines
Jardiance is not known to interact with any vaccines. But this doesn’t mean interactions with vaccines can’t happen or won’t be identified later.
Because of this, talk with your doctor or pharmacist before receiving any vaccines while taking Jardiance.
Jardiance and lab tests
Jardiance may interact with a urine test used to check for glucose (sugar) in your urine. Taking Jardiance and having this test may lead to higher-than-usual glucose levels in your urine glucose test.
Jardiance may also interact with a blood test that determines how well your blood sugar levels are being managed. This test is called a 1,5-anhydroglucitol (1,5-AG) assay. Taking Jardiance and having this test may lead to inaccurate results.
Because of this, talk with your doctor or pharmacist before having any lab tests while taking Jardiance.
Jardiance and cannabis or CBD
Jardiance is not known to interact with cannabis (commonly called marijuana) or cannabis products such as cannabidiol (CBD). But this doesn’t mean interactions can’t happen or won’t be identified later.
As with any drug or supplement, tell your doctor before taking cannabis with Jardiance.
Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees.
Health factors and Jardiance
Certain medical conditions or other health factors may increase the risk of interactions with Jardiance. Keep in mind that interactions could lead to side effects or affect how well the drug works. Before taking Jardiance, tell your doctor about your health history. They’ll determine whether Jardiance is right for you.
These health conditions or other factors might interact with Jardiance:
- kidney problems
- dehydration
- genital yeast infection or urinary tract infection
- pancreas problems
- upcoming surgeries or medical procedures
- type 1 diabetes
- low salt diet or ketogenic diet
- pregnancy or breastfeeding
- past allergic reaction to Jardiance
Questions about Jardiance and interactions
Below are answers to some common questions about Jardiance and possible interactions.
Can you take ibuprofen with Jardiance?
Possibly. There are no known interactions between ibuprofen and Jardiance. Usually, it is safe to take these drugs together.
However, talk with your doctor about whether they feel it’s safe for you to take these medications together. There may be certain situations where you should not take ibuprofen with Jardiance, such as if you’re taking Jardiance for heart failure or kidney disease.
If you have more questions about this, talk with your doctor or pharmacist.
Can you take metformin, glipizide, and Jardiance together?
Typically, yes. Doctors may prescribe metformin (Fortamet, Glumetza), glipizide, and Jardiance together to help manage your blood sugar levels with type 2 diabetes.
However, all three of these medications lower your blood sugar levels. So taking them together may put you at increased risk for low blood sugar levels.
If you have more questions about taking metformin, glipizide, and Jardiance together, talk with your doctor or pharmacist.
Can you take Lantus and Jardiance together?
Typically, yes. Doctors may prescribe Lantus (insulin glargine) and Jardiance together to manage your blood sugar levels.
However, taking Jardiance with insulin medications can increase your risk of low blood sugar. To lower this risk, your doctor may reduce your Lantus dosage.
If you have more questions about taking Lantus and Jardiance together, talk with your doctor or pharmacist.
Preventing Jardiance interactions
You may be able to help avoid certain interactions with Jardiance. Before taking this drug, you may want to discuss possible interactions with your doctor and pharmacist.
Things to consider include:
- Whether you drink alcohol or use cannabis.
- Other medications and herbs you take, as well as vitamins and supplements. Your doctor or pharmacist can help you fill out a medication list.
- What to do if you’re prescribed a new drug while taking Jardiance.
Taking Jardiance exactly as prescribed can also help prevent interactions.
Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.