Cold sores or fever blisters are symptoms of a viral infection caused by the herpes simplex virus (HSV-1). These sores are transmissible, and you contract it through direct contact with someone who has the virus.
Cold sores usually present as small blisters filled with fluid. They may be painful or itchy and typically appear on or around the lips. You may also develop cold sores in other parts of the mouth or face.
You may have heard that Vaseline, a common brand of petroleum jelly, may help with cold sores. While it may ease some pain, there is no evidence it is effective.
Need a prescription or refill? You can get discreet and expert on-demand care in as little as 15 minutes. For $29, answer a few questions online and get a treatment plan from a US-licensed healthcare professional. Get started here.
Is Vaseline an effective treatment for cold sores?
Some people may find Vaseline lowers some of the discomfort cold sores can cause. It moisturizes the affected area, preventing cracking or bleeding, and can serve as a protective layer over the cold sore.
Vaseline does not heal cold sores or remove the virus. HSV-1 may resolve on its own within 7 to 14 days.
Vaseline, or petroleum jelly, may help relieve dryness and itchiness by acting as a moisturizer. This might help prevent more cold sores from developing. It may also prevent further cracking and drying associated with cold sores.
Evidence does not indicate Vaseline helps cold sores heal faster. The healing process for cold sores varies from person to person depending on various factors, such as immune response and symptom severity.
How to use Vaseline for cold sores
Consulting a healthcare professional is always recommended when managing pain. If you’re experiencing mild discomfort from cold sores, Vaseline may help.
To use Vaseline as a treatment for cold sores, follow these steps:
- Prepare the area: Clean around cold sores with water and a mild soap. Pat the area dry with a clean towel or allow it to air dry. This step may help prevent the spread of cold sores.
- Patch test: Before applying the Vaseline, test the product on a small area. Only apply to the whole area if the patch test confirms you are not allergic to Vaseline.
- Application: Apply Vaseline to the cold sores directly a few times throughout the day. When applying, a thin layer is generally enough. Excessive amounts may delay the healing process or create an uncomfortable, greasy sensation.
- Wash your hands: Remember to wash your hands after touching cold sores.
Although Vaseline is a commonly used brand of petroleum jelly, other similar products may also be effective. Look for pure petroleum jelly products without added fragrances or other ingredients.
If you need help covering the cost of medications, the free Optum Perks Discount Card could help you save up to 80% on prescription drugs. Plus, you can now get them delivered to your home in as little as 3 days. Search for your medication here.

Free prescription coupons
Seriously … free. Explore prices that beat the competition 70% of the time.
Get free cardNatural remedies for cold sores
Some natural strategies for cold sores may include:
- Applying a cool compress: Using ice wrapped in a cloth or an ice pack on the cold sore for 5 to 10 minutes a few times daily may help reduce pain and swelling. Ice works by numbing the area and providing temporary relief.
- Using aloe vera gel: Aloe vera extracts may help promote healing and lower discomfort when you apply it directly to your cold sore. Aloe vera has been used for centuries for its anti-inflammatory and moisturizing effects. But it’s a good idea to test a small area before putting it on your lesions.
- Zinc oxide: Topical creams or ointments containing zinc oxide may help dry out the cold sore. But more research is necessary to confirm its effectiveness.
- Increasing lysine intake: Including lysine-rich foods in your diet, such as dairy products, fish, and legumes, may help with HSV infections. Some 2023 research suggests that 3 to 5 grams of lysine per day may be effective against future outbreaks.
- Keeping the area clean: Gently washing the cold sore with mild soap and water can help prevent the risk of infection and promote healing. Remember to pat the area dry gently afterward.
Here’s what not to do when using natural remedies for cold sores:
- Picking or popping the cold sore: Picking at the sore can lead to further infection and scarring and delay healing.
- Applying toothpaste: Despite anecdotal reports supporting its use, no scientific studies recommend it for treating cold sores.
- Applying witch hazel: Witch hazel has astringent properties, but limited scientific evidence supports its effectiveness in treating cold sores.
Medications for cold sores
Treatments for cold sores may include:
- Over-the-counter (OTC) medications: You can apply creams or ointments containing antiviral ingredients, such as docosanol (Abreva), directly to your cold sore. Applying this medication at the first sign of symptoms may shorten the healing time.
- Prescription medications: Oral antiviral drugs are available by prescription only. These medications are more effective when started early and can help reduce the frequency and severity of cold sore flare-ups. Examples include:
- acyclovir (Zovirax)
- famciclovir (Famvir)
- valacyclovir (Valtrex)
Aciclovir also comes in cream and ointment form.
It’s important to note that while these medications may provide relief, they do not cure cold sores or HSV-1. The virus might stay inactive in your body for a long time.
Download the free Optum Perks Discount Card to save up to 80% on many prescription medications. Plus, you can now get them delivered to your home in as little as 3 days. Search for your medication here.
Summary
While Vaseline may help relieve symptoms of cold sores for some people, it does not cure cold sores or the virus that causes them. OTC and prescription medications may be more effective at managing discomfort.
If you have concerns about your cold sores or experience frequent or severe outbreaks, consider talking with a healthcare professional to determine the best treatment options according to your needs.
Download the free Optum Perks Discount Card to save up to 80% on many prescription medications. Plus, you can now get them delivered to your home in as little as 3 days. Search for your medication here.
