Skip to main content
Medically Approved

Apriso dosage: A detailed guide

twitter share buttonfacebook share buttonlinkedin share buttonemail article button
Form and strengthDosageFAQHow it’s takenCouponOverdoseAsk your doctor
Doctors prescribe Apriso for ulcerative colitis in adults. You take it by mouth once per day in the morning.
Medically reviewed by Christina Bookwalter PharmD, MS MEd, BCPS, BCACP
Updated on

This article describes Apriso’s dosage and strength and gives details on how to take it. You’ll also find information on cost savings and coupon options for Apriso. If you want to know more about Apriso, see this overview article. It covers details about the drug’s uses and side effects, ways to save on cost, and more.

Apriso is a brand-name medication that comes as an extended-release (ER) oral capsule. Extended release means the drug is slowly released into your body over a long period of time. It’s available in a generic version called mesalamine. This article describes dosages of Apriso.

Need a diagnosis or prescription quickly? For certain health conditions, Optum Perks offers personalized on-demand care with no appointment required. For $25, answer a few questions online and receive a diagnosis and treatment plan from a board certified healthcare professional in 15 minutes or less. Get started here.

Form and strength of Apriso

Apriso comes as follows:

  • Form: oral capsule that you swallow
  • Strength: 0.375 grams (g)

Dosage of Apriso

This article describes the recommended dosage for Apriso. The drugmaker provides these dosages.

If your doctor prescribes this medication, you should follow the dosage they prescribe. Your doctor will determine the dosage that best meets your needs. Do not change your dosage of Apriso without your doctor’s recommendation.

Usual recommended dosage of Apriso in adults

Apriso is approved to be used for ulcerative colitis (UC) in adults.

The recommended dosage of Apriso is:

  • Dose: 1.5 g (four 0.375 g capsules)
  • Frequency: once per day in the morning

Missed dose of Apriso

Talk with your doctor or pharmacist right away if you realize you forgot to take a dose of Apriso. They may advise you to take the missed dose. Or they may advise you to skip it and take your next dose as scheduled.

For tips on how to plan your doses of Apriso and avoid missing a dose, read this article. You could also try:

  • downloading a reminder app on your phone
  • setting an alarm
  • putting a note where you’ll see it, such as on your calendar, bathroom mirror, or bedside table

Frequently asked questions

Below are answers to some commonly asked questions about Apriso and its dosage.

Man on phone in bed

100% online care

Treatment plans in 15 minutes or less for 40+ conditions.

Start consult now

How does the dosage of Apriso compare with the dosage of Pentasa or Lialda?

Apriso, Pentasa, and Lialda are all used to treat UC. They all contain the active ingredient mesalamine. An active ingredient is what makes a drug work.

The recommended dosages of Apriso, Pentasa, and Lialda for adults are outlined in the following table.

ConditionApriso dosagePentasa dosageLialda dosage
Ulcerative colitis1.5 g once per day in the morning1 g four times per day2.4–4.8 g once per day

If you have more questions about how the dosage of Apriso compares with the dosage of Pentasa or Lialda, talk with your doctor.

Is Apriso taken long term?

Possibly. UC is a chronic (long-term) condition. You may have periods of symptoms or no symptoms at all. This is called remission.

Apriso helps maintain remission of UC. So, your doctor may prescribe Apriso as a long-term treatment. If you and your doctor determine that it’s safe and effective for your condition, you’ll likely take it long term.

If you have questions about how long you should take Apriso, talk with your doctor.

How Apriso is taken

You’ll swallow Apriso capsules once per day in the morning. It can be taken with or without food. Be sure to stay hydrated by drinking plenty of fluids while taking Apriso.

Your doctor may advise that you take this medication around the same time each day. This helps keep a consistent amount of the drug in your body. And that can help the drug work more effectively.

Swallow the capsules whole. Don’t break, cut, crush, or chew them. If it’s hard for you to swallow capsules, view this article. It provides suggestions on how to swallow medications that come in pill form.

Also, be sure to talk with your doctor or pharmacist if you’re having difficulty taking your medication. They can offer recommendations about taking it.

Apriso coupon

Visit this page to access Optum Perks coupons and get price estimates for Apriso when you use the coupons. These coupons can provide significant savings on your prescription costs.

Note: Optum Perks coupons cannot be used with insurance copays or benefits.

Download the free Optum Perks Discount Card to save up to 80% on some prescription medications.

Pill bottle with text 'Starts at $4'

Free prescription coupons

Seriously … free. Explore prices that beat the competition 70% of the time.

Get free card

Overdose of Apriso

It’s important that you do not take more Apriso than your doctor prescribes. Doing so can lead to harmful effects.

Symptoms of Apriso overdose

Symptoms of an overdose can include:

What to do if you take too much Apriso

If you think you’ve taken too much Apriso, call your doctor or pharmacist right away. Or you could call 800-222-1222 to speak with someone at America’s Poison Centers. You can also use its online resource. If you have severe symptoms, call 911 or a local emergency number immediately. You can also go to the closest emergency room.

What to ask your doctor

This article describes the usual recommended dosage for Apriso. If your doctor prescribes this medication, they’ll determine the dosage that’s best for you.

Do not change your dosage of Apriso without your doctor’s recommendation. You should take Apriso exactly as your doctor prescribes it. Let your doctor know if you have concerns or questions about your treatment plan.

Here’s a list of some possible questions you may want to ask your doctor:

  • How long will I need to take Apriso?
  • Should I continue taking Apriso if I don’t have any symptoms?
  • Would other forms of mesalamine (the active ingredient in Apriso) work better for my condition?

Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

Article resources