Key takeaways
- Antibiotic eye drops treat bacterial eye infections by killing bacteria that enter the cornea. They should clear an infection within 3 days, but they have no effect on viral infections.
- Common antibiotic eye drops include azithromycin (Azasite), ciprofloxacin (Ciloxan), moxifloxacin (Vigamox), and erythromycin ophthalmic (Ilotycin). A doctor must prescribe these medications.
- Bacterial eye infections often cause eye redness, pus discharge, and matted eyelashes in the morning, while viral infections typically cause watery discharge and almost always affect only one eye. Contact a doctor if symptoms don’t improve within 3 days of treatment.
Overview
Viruses and bacteria can cause eye infections. An eye infection, such as pink eye, may cause discomfort, including redness, tearing, and pus discharge.
Antibiotic eye drops are the first-line treatment for eye infections. Doctors typically recommend antibiotic eye drops for treating bacterial eye infections. A doctor may prescribe antibiotic eye drops if you have developed a bacterial infection. However, other treatment options for eye infections are available, including oral medications.
Need a diagnosis or prescription quickly? Optum Perks offers personalized on-demand care in as little as 15 minutes. For $29, answer a few questions online and receive a diagnosis and treatment plan from a US-licensed healthcare professional. Get started here.
What are antibiotic eye drops?

A doctor may prescribe antibiotic eye drops to people with a bacterial eye infection. These medications kill the bacteria that have entered the cornea, which is the transparent layer of the front of the eye.
Antibiotic eye drops may look similar to artificial tears. However, they contain a medication to treat infections.
There are various antibiotic eye drops available for treating eye infections, including:
- azithromycin (Azasite)
- bacitracin (Ocu-Tracin)
- ciprofloxacin (Ciloxan)
- erythromycin ophthalmic (Ilotycin)
- gatifloxacin (Zymar)
- gentamicin (Garamycin)
- moxifloxacin (Vigamox)
- ofloxacin ophthalmic (Ocuflox)
- polymyxin B-trimethoprim (Polytrim)
- tobramycin (Tobrex)
The type of antibiotic eye drops doctors may prescribe varies depending on the type of infection you have.
The eyedrops should clear a bacterial infection within 3 days. If it doesn’t clear in this time, you should contact your eye doctor for further advice.
If you need help covering the cost of medications, the free Optum Perks Discount Card could help you save up to 80% on prescription drugs. Plus, you can now get them delivered to your home in as little as 3 days. Search for your medication here.

Free prescription coupons
Seriously … free. Explore prices that beat the competition 70% of the time.
Get free cardCommon questions about antibiotic eye drops
Here are some common questions about antibiotic eye drops and their answers.
Are all eyedrops for bacterial infections prescription-only?
A doctor must prescribe you antibiotic eye drops. If you suspect you may have an eye infection, consider contacting a doctor, as they can recommend the most appropriate treatment for your eye condition.
Are there any over-the-counter options?
Over-the-counter options may help with the symptoms of an eye infection. However, you should contact a doctor if an infection gets worse or does not show signs of improvement.
You may also consider contacting a doctor if you experience eye pain or if you have any other concerns about your eyes.
Do eye drops have side effects?
Antibiotic eye drops may have side effects, including:
- blurred vision
- mild stinging
- a strange taste in your mouth
Some people may also develop an allergic reaction after using antibiotic eye drops. The symptoms of an allergic reaction may include:
- skin rash
- redness or swelling in your eyes and eyelids
- swelling in your face or lips
- difficulty breathing
If you experience any signs of an allergic reaction, you should immediately contact a doctor or healthcare professional.
Topical and oral options for eye infections
For bacterial infections, topical ointments include neomycin polymyxin (Bacitracin) and erythromycin.
However, topical antibiotics do not enter the eye as well as drops, so once the infection reaches inside the eye, an eye doctor, or ophthalmologist, relies on intravenous (IV) and intraocular drug administration. Intraocular is when the medication is injected directly into a part of the eye.
Viral infection treatments
Instead of antibiotic eye drops, doctors may recommend topical or oral medications for treating eye infections. Typically, doctors only use topical and oral antibiotics for viral eye infections. These may include:
- topical aciclovir (Zovirax)
- systemic aciclovir (Zovirax)
- topical ganciclovir (Virgan)
- topical trifluridine (Viroptic)
- topical idoxuridine (Dendrid, Herplex, Stoxil)
- famciclovir (Famvir) tablets
The type of medication a doctor may prescribe you may vary depending on the infection that requires treatment.
Viral infection vs. bacterial infection
Viruses and bacteria can both cause eye infections. While antibiotic eye drops can effectively treat bacterial infections, antibacterial eye drops have no effect if the infection is viral.
People with a viral eye infection may experience symptoms, including:
- eye redness
- feeling as though something is in your eye
- light sensitivity
- itching
- burning
- watery discharge
Viral eye infections almost always affect only one eye.
People with a bacterial eye infection may experience symptoms such as:
- eye redness
- feeling as though something is in your eye
- matting of your eyelashes in the morning
- white-yellow pus discharge
- swollen lymph nodes
- the development of small bumps called papillae in the lining of your eyelids, known as the palpebral conjunctiva
Bacterial eye infections may occur in only one eye but can eventually end up affecting both.
Doctors may prescribe antibiotic eye drops or a topical ointment to treat bacterial infections. In some cases, they may also suggest taking oral antibiotics.
If you have a viral infection, a doctor may recommend taking antiviral medications, depending on the severity. However, mild infections may go away without treatment within a couple of weeks and without any long-term consequences.
What can cause bacterial eye infections?
Bacterial eye infections are the most common type of eye infection, and touching your eyes without first washing your hands could lead to a bacterial infection.
Other common causes of bacterial eye infections have a link to contact lens use. Wearing dirty contact lenses or sleeping in lenses that are not for overnight use may cause an infection.
Conjunctivitis is the most common eye infection, and a virus is often the cause. Other eye infections may include infectious keratitis and endophthalmitis.
When to contact a doctor
If you think you may have an eye infection, you should contact a doctor regardless of the type of infection. They can diagnose which infection affects your eyes and recommend the most appropriate treatment for your condition.
You should also contact a doctor if, about 3 days after starting your treatment, your eye infection does not improve.
Online care services, including Optum Perks Online Care, may make getting treatment easier. With these services, you can submit an online form answering a few questions about your symptoms, and a US-licensed healthcare professional will respond soon after to prescribe a treatment plan.
Summary
Antibiotic eye drops are often the first-line treatment for bacterial eye infections. However, they are ineffective in treating viral infections. But antiviral eyedrops are available for several common viral eye infections. Doctors may also prescribe topical ointments or oral tablets for treating some eye infections.
People with a bacterial eye infection often experience redness in the affected eye, the feeling of a foreign body, and a discharge of pus.
If you suspect you may have an eye infection, you should consider contacting a doctor or healthcare professional. They can recommend the most appropriate treatment for your infection.
Download the free Optum Perks Discount Card to save up to 80% on many prescription medications. Plus, you can now get them delivered to your home in as little as 3 days. Search for your medication here.