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Dicyclomine oral capsule side effects: A detailed guide

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More common side effectsMild side effectsSerious side effectsFAQCouponSide effects in detailWarningsAsk your doctor
Dicyclomine oral capsule is prescribed for treating symptoms of irritable bowel syndrome (IBS) in adults. It’s an anticholinergic drug that may cause mild or serious side effects. These include dizziness and dry mouth.
Medically reviewed by Amber R. Watson, PharmD
Updated on

This article describes possible side effects of dicyclomine oral capsule. You’ll also find information on cost savings and coupon options for dicyclomine. You can explore this overview article to learn more about dicyclomine oral capsule, including the drug’s uses, side effects, and more.

Dicyclomine oral capsule is a generic medication. It isn’t available in a brand-name version.

Dicyclomine also comes in other oral forms and an injectable form. But those forms aren’t described in this article. To learn more about those forms, talk with your doctor.

More common side effects of dicyclomine

Dicyclomine oral capsule may cause mild or serious side effects. Below are some of the more common side effects of this medication.

Commonly reported side effects of dicyclomine oral capsule include:

  • dizziness
  • dry mouth
  • blurry vision
  • nausea
  • sleepiness

Mild side effects of dicyclomine

Dicyclomine may cause certain mild side effects. Most often, mild side effects are temporary and can be managed easily. Tell your doctor or pharmacist if you have side effects that don’t go away or become bothersome.

Mild side effects of dicyclomine oral capsule that occurred in studies include:

* An allergic reaction is possible with dicyclomine oral capsule. But it wasn’t reported in the drug’s studies.

Dicyclomine oral capsule may cause more mild side effects than those listed above. For details, see the drug’s prescribing information.

Serious side effects of dicyclomine

Dicyclomine may cause certain serious side effects. If you have any serious side effects from dicyclomine oral capsule, call your doctor right away. But if you think you’re having a medical emergency or your side effects feel life threatening, act immediately. Call 911 or a local emergency number, or go to the nearest emergency room.

After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. Visit MedWatch’s website if you’d like to notify the FDA about a side effect you’ve had with dicyclomine.

Serious side effects of dicyclomine oral capsule that occurred in studies include:

* To learn more about this side effect, see the “Side effects of dicyclomine in detail” section below.
† An allergic reaction is possible with dicyclomine oral capsule. But it wasn’t reported in the drug’s studies.

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Common questions about side effects of dicyclomine

Here are answers to some common questions about side effects of dicyclomine oral capsule. If you have other questions, talk with your doctor or pharmacist.

Can dicyclomine cause weight loss?

No, it’s not thought to cause weight loss. It’s not a side effect reported in studies of dicyclomine.

Dicyclomine belongs to a group of drugs called anticholinergics. Drugs in this group often cause weight gain as a side effect, but not weight loss. But neither weight gain nor weight loss were reported in studies of dicyclomine.

Talk with your doctor if you have concerns about your weight and your medications affecting it.

Can dicyclomine cause certain side effects in older adults?

It’s possible. Dicyclomine isn’t known to cause side effects in older adults that are different from those in younger adults. (Older adults usually refers to people ages 65 years and older.) But older adults may have a higher risk of psychosis or delirium.*

In general, older adults may also have liver or kidney problems. These conditions can increase their risk of side effects from dicyclomine. For this reason, doctors may prescribe a lower dosage of dicyclomine for older adults. Doing so can help reduce the risk of side effects from the drug.

If you have questions about this, talk with your doctor or pharmacist.

* To learn more about this side effect, see the “Side effects of dicyclomine in detail” section below.

Does dicyclomine cause long-term side effects?

Yes, in some cases dicyclomine oral capsule may cause long-term side effects. With dicyclomine, the risk of these side effects lasts throughout treatment. The side effects may begin during treatment and last for a long time as you continue treatment. But they typically go away if the drug is stopped.

Examples of long-term side effects reported with dicyclomine oral capsule include:

* To learn more about this side effect, see the “Side effects of dicyclomine in detail” section below.

Talk with your doctor to learn more about these side effects and how to manage them. Your doctor can tell you more about how long these side effects of dicyclomine may last.

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Visit this page to access Optum Perks coupons and get price estimates for dicyclomine when you use the coupons. These coupons can provide significant savings on your prescription costs. 

Note: Optum Perks coupons cannot be used with insurance copays or benefits.

Side effects of dicyclomine in detail

Below you’ll find details on some of the side effects of dicyclomine oral capsule.

Central nervous system depression

In studies, the side effect central nervous system (CNS) depression was rare in people taking dicyclomine oral capsule. This side effect may be serious.

Your CNS is made up of your brain and spinal cord. It’s your body’s command center because it communicates to coordinate actions throughout your body. A slowing of CNS functions is called CNS depression.

Symptoms of CNS depression include confusion and memory problems. Other symptoms are problems with coordination and inappropriate habits or traits. You could also have difficulty driving or operating machinery.

Consuming alcohol can increase the risk of CNS depression with dicyclomine oral capsule. 

Ways to manage

If you experience symptoms of CNS depression, tell your doctor. They will advise you based on your symptoms. For example:

  • For mild symptoms, they may suggest waiting to see whether your symptoms go away on their own. They may recommend a treatment to help relieve them.
  • For serious symptoms, they will likely suggest you stop taking dicyclomine.

When you first begin taking dicyclomine, avoid driving or operating machinery until you know how the drug will affect you. This will lower your risk of an accident if CNS depression does occur.

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Heatstroke

In studies, heatstroke was rare in people taking dicyclomine oral capsule. This side effect is serious.

With heatstroke, your core body temperature reaches 104°F (40°C) or higher. Symptoms may include high fever, muscle cramps, confusion, and irregular or erratic behavior.

Exposure to high environmental temperatures increases the risk of heatstroke with dicyclomine oral capsule.

Ways to manage

Heatstroke is life threatening. If you have symptoms of heatstroke, seek emergency medical help (such as calling 911).

If you experience this side effect during dicyclomine treatment, your doctor will likely have you stop taking the drug.

Psychosis or delirium

In studies, psychosis or delirium was rare in people taking dicyclomine oral capsule. This side effect may be serious.

With psychosis, you have an impaired reality. Symptoms may include:

  • disorganized or impulsive behavior
  • hallucinations (seeing or hearing things that aren’t real)
  • expressing little or no emotion

With delirium, you experience a sudden change in your thinking and alertness. Symptoms may include:

  • difficulty concentrating
  • confusion or disorientation
  • mood changes

People ages 65 years and older generally have a higher risk of psychosis or delirium with dicyclomine oral capsule.

Ways to manage

If you experience symptoms of psychosis or delirium, tell your doctor. They’ll likely recommend stopping treatment with dicyclomine. These symptoms typically go away within a day once treatment with dicyclomine is stopped.

Allergic reaction

For some people, dicyclomine oral capsule can cause an allergic reaction. But this side effect wasn’t reported in the drug’s studies.

Symptoms can be mild or serious, and they may include:

  • itchiness
  • skin rash
  • swelling under the skin, usually affecting eyelids, lips, hands, or feet
  • swelling of the mouth, tongue, or throat, which can make it hard to breathe
  • flushing (temporary warmth, redness, or deepening of skin color)

Ways to manage

For mild allergic reaction symptoms, such as a mild rash, call your doctor right away. They may recommend treatments to help manage your symptoms. They’ll also let you know whether you should keep taking the medication.

For severe allergic reaction symptoms, such as swelling or trouble breathing, call 911 or your local emergency number right away. These symptoms require immediate medical care because they can become life threatening. If you’ve had a serious allergic reaction to dicyclomine oral capsule, your doctor may recommend taking a different medication instead.

Warnings for dicyclomine

Below are some factors you may want to discuss with your doctor before taking dicyclomine oral capsule.

Warnings

It may not be safe for you to take dicyclomine oral capsule if you have specific health conditions. These are sometimes called drug-condition interactions. Other things may also affect whether dicyclomine oral capsule is a safe treatment option for you.

Before taking dicyclomine oral capsule, tell your doctor about your health and medications you take. Things to consider include:

Dicyclomine and pregnancy

It’s not known whether dicyclomine oral capsule should be taken during pregnancy. If you’re planning a pregnancy or can become pregnant, talk with your doctor before taking this medication.

Dicyclomine and breastfeeding

Dicyclomine oral capsule should not be taken while breastfeeding. If you’re currently breastfeeding or planning to do so, talk with your doctor before taking this medication. Your doctor may recommend other ways to feed your child during treatment with dicyclomine.

Dicyclomine and alcohol

Dicyclomine oral capsule is known to interact with alcohol.

Consuming alcohol raises your risk of central nervous system (CNS) depression as a side effect from taking dicyclomine. Drinking alcohol also can worsen other side effects of dicyclomine, including nausea, dry mouth, and dizziness.

If you drink alcohol, talk with your doctor about whether it’s safe to consume it during your treatment with dicyclomine oral capsule.

What to ask your doctor

This article describes common and serious side effects of dicyclomine oral capsule. If your doctor prescribes this medication, they can discuss possible side effects with you. Let your doctor know if you have concerns or questions about treatment with this medication.

Here’s a list of some possible questions you may want to ask your doctor:

  • How do side effects of dicyclomine oral capsule compare with other treatments for irritable bowel syndrome (IBS)?
  • Does my risk of side effects depend on the dicyclomine oral capsule dosage I’m prescribed?
  • If I have side effects from taking dicyclomine oral capsule, can a lower dosage be prescribed?

Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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