This article describes Auvelity’s dosages and strength and gives details on how to take it. You’ll also find information on cost savings and coupon options for Auvelity. If you want to know more about Auvelity, see this overview article. It covers details about the drug’s uses and side effects, ways to save on cost, and more.
Auvelity is a brand-name medication that comes as an extended-release oral tablet. (“Extended release” means the drug is slowly released into your body over a long period of time.) It isn’t available in a generic version.
Auvelity has a boxed warning. A boxed warning is the most serious warning from the Food and Drug Administration (FDA). For details, see the end of this article.
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Form and strength of Auvelity
Auvelity comes as follows, with strength in milligrams (mg):
- Form: an extended-release oral tablet, which you’ll take by swallowing
- Strength: dextromethorphan 45 mg/bupropion 105 mg
Dosage of Auvelity
This article describes the recommended dosages for Auvelity. The drugmaker provides these dosages. In some cases, doctors may adjust your dosage from those shown below.
If your doctor prescribes this medication, you should follow the dosage they prescribe. Your doctor will determine the dosage that best meets your needs. Do not change your dosage of Auvelity without your doctor’s recommendation.
Usual recommended dosages of Auvelityin adults
Usually, doctors prescribe a standard dosage of Auvelity.
The recommended dosage of Auvelity for major depressive disorder in adults is typically as follows:
- Starting dosage: one tablet once per day in the morning for 3 days
- Maintenance dosage: one tablet twice per day
- Maximum dosage: one tablet twice per day
When you take Auvelity twice per day, the doses need to be spaced at least 8 hours apart. It’s important to take your doses at the same times each day.
You can take Auvelity with or without food. You’ll need to swallow Auvelity whole. Do not crush, chew, or cut the tablet.
Frequently asked questions
Below are answers to some commonly asked questions about Auvelity and its dosage.
What is Auvelity’s half-life?
A drug’s half-life is the amount of time it takes for your body to remove half of the amount of a drug from your system. The length of time it takes varies from one medication to another. Knowing about a drug’s half-life helps drugmakers know how often you need to take a drug.
There are two active ingredients in Auvelity. (An active ingredient is what makes a drug work.) The first is dextromethorphan. Its half-life is 22 hours. The other active ingredient is bupropion. Its half-life is 15 hours. Based on this information, the maintenance dosage of one tablet twice per day helps keep a steady level of Auvelity in your body.
You can talk with your doctor or pharmacist to learn more about Auvelity’s half-life.
Can I take Auvelity at night?
Yes, after the first 3 days, you’ll take Auvelity twice per day. The two doses need to be spaced at least 8 hours apart. So, you’ll take one dose in the morning and another dose at night.
Follow your doctor’s instructions for taking Auvelity. If you have questions or don’t understand the instructions, talk with your doctor or pharmacist.
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Get free cardOverdose of Auvelity
It’s important that you do not take more Auvelity than your doctor prescribes. Doing so can lead to harmful effects.
Symptoms of Auvelity overdose
Symptoms of an overdose can include:
- nausea
- vomiting
- slowed breathing
- fast heart rate
- coordination problems
- hallucinations
- muscle pain
- seizures
- blurry vision
- loss of consciousness or coma
What to do if you take too much Auvelity
If you think you’ve taken too much Auvelity, call your doctor or pharmacist right away. Or you could call 800-222-1222 to speak with someone at America’s Poison Centers. You can also use its online resource. If you have severe symptoms, call 911 or a local emergency number immediately. You can also go to the closest emergency room.
Boxed warning for Auvelity
Auvelity has a boxed warning for the risk of suicidal thoughts and behaviors. A boxed warning is the most serious warning from the Food and Drug Administration (FDA).
Taking Auvelity may increase the risk of suicidal thoughts or behaviors in people ages 24 years and younger. The risk is highest in the first few months of treatment and when there’s a change in dosage. Keep in mind that depression and other mental health problems can also cause suicidal thoughts and actions.
Due to this boxed warning, Auvelity isn’t approved for use in children. Doctors will monitor anyone who starts treatment with Auvelity for new or worsening mental health symptoms. They’ll also ask family and caregivers to watch for certain signs and symptoms. Symptoms may include changes in thoughts, feelings, behaviors, or mood.
If you have thoughts of suicide during Auvelity treatment, call the Suicide and Crisis Lifeline by dialing 988. Or tell your doctor right away. You can also refer to this Suicide Prevention Guide for ways to get help and support.
Talk with your doctor or pharmacist to learn more.
Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.