Anastrozole oral tablet interactions: A detailed guide

This article describes possible interactions with anastrozole oral tablet. Interactions can cause a drug to have a different effect on the body than expected. Interactions can occur due to medications, alcohol, or certain health conditions.

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Other drugs and anastrozole

The drugs in the list below may interact with anastrozole oral tablet. This article doesn’t include all drugs that may interact with anastrozole.

Drug classes or drugs that may interact with anastrozole oral tablet include:

• estrogen (Menest, Premarin, other estrogen-containing products):
  • what might happen: can make anastrozole less effective
• prasterone (Intrarosa):
  • what might happen: can make anastrozole less effective
• tamoxifen (Soltamox):
  • what might happen: can make anastrozole less effective

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Other interactions and anastrozole

Interactions can occur with supplements, foods, vaccines, and some lab tests. Below you can learn whether anastrozole oral tablet has these interactions. 

The information below doesn’t include all other possible interactions with anastrozole.

Anastrozole and supplements

Before taking anastrozole oral tablet, tell your doctor and pharmacist about any herbs you take, as well as vitamins and supplements. Doing so may help you avoid interactions.

Anastrozole oral tablet may interact with dehydroepiandrosterone (DHEA). This supplement is often used for sexual health, mood, pro-aging effects, and more. Taking anastrozole oral tablet and DHEA can make anastrozole less effective. It can also make DHEA less effective.

If you have questions about interactions that may affect you, talk with your doctor or pharmacist.

Anastrozole interactions with herbs

Anastrozole oral tablet isn’t known to interact with any herbs. But this doesn’t mean interactions with herbs can’t happen or won’t be identified later.

Because of this, ask your doctor or pharmacist before taking any of these products while taking anastrozole oral tablet.

Anastrozole interactions with vitamins

Anastrozole oral tablet isn’t known to interact with any vitamins. But this doesn’t mean interactions with vitamins can’t happen or won’t be identified later.

Because of this, ask your doctor or pharmacist before taking any of these products while taking anastrozole oral tablet.

Anastrozole and food

Anastrozole oral tablet isn’t known to interact with foods. But this doesn’t mean interactions with foods can’t happen or won’t be identified later. Anastrozole can be taken with or without food.

Because of this, talk with your doctor or pharmacist about what foods to avoid when taking anastrozole oral tablet.

Anastrozole and vaccines

Anastrozole oral tablet isn’t known to interact with any vaccines. But this doesn’t mean interactions with vaccines can’t happen or won’t be identified later.

Because of this, talk with your doctor or pharmacist before receiving any vaccines while taking anastrozole oral tablet.

Anastrozole and lab tests

Anastrozole oral tablet isn’t known to interact with lab tests. But this doesn’t mean interactions with lab tests can’t happen or won’t be identified later.

Because of this, talk with your doctor or pharmacist before having any tests while taking anastrozole oral tablet.

Anastrozole and cannabis or CBD

Anastrozole oral tablet isn’t known to interact with cannabis (commonly called marijuana) or cannabis products such as cannabidiol (CBD). But this doesn’t mean interactions can’t happen or won’t be identified later.

As with any drug or supplement, tell your doctor before taking cannabis with anastrozole.

Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees.

When to avoid anastrozole

Certain health conditions or other factors could increase some risks with anastrozole oral tablet. Because of this, doctors may not prescribe anastrozole in these cases. These health conditions or other factors are called contraindications.

Here’s a contraindication for anastrozole:

• Past allergic reaction to anastrozole: If you’ve ever had an allergic reaction to anastrozole oral tablet, taking it again may cause a life threatening allergic reaction.

Before you start taking anastrozole, talk with your doctor about anastrozole contraindications. Your doctor can recommend whether you should take anastrozole.

Anastrozole interactions with alcohol

Anastrozole oral tablet isn’t known to interact with alcohol. If you drink alcohol, talk with your doctor about whether it’s safe to consume it while taking anastrozole oral tablet.

Health factors and anastrozole

Certain medical conditions or other health factors may increase the risk of interactions with anastrozole oral tablet. Keep in mind that interactions could lead to side effects or affect how well the drug works. Before taking anastrozole, tell your doctor about your health history. They’ll determine whether anastrozole is right for you.

These health conditions or other factors might interact with anastrozole oral tablet:

• premenopause
• heart problems
• high cholesterol
• liver disease
• osteoporosis
• pregnancy or breastfeeding
• past allergic reaction to anastrozole

Preventing anastrozole interactions

You may be able to help avoid certain interactions with anastrozole oral tablet. Before taking this drug, you may want to discuss possible interactions with your doctor and pharmacist.

Things to consider include:

• Whether you drink alcohol or use cannabis.
• Other medications and herbs you take, as well as vitamins and supplements. Your doctor or pharmacist can help you fill out a medication list.
• What to do if you’re prescribed a new drug while taking anastrozole oral tablet.

Taking anastrozole exactly as prescribed can also help prevent interactions.

What to ask your doctor

If you have questions about anastrozole and possible interactions, talk with your doctor.

Questions you may want to ask your doctor include:

• Could I still take anastrozole oral tablet even if it interacts with a health condition I have?
• Should I tell you if I start taking another medication or supplement during my anastrozole treatment?
• Do other drugs that could treat my condition have similar interactions?

Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.