Prempro dosage: A detailed guide

This article describes Prempros oral tablet’s dosages and strengths and gives details on how to take it. You’ll also find information on cost savings and coupon options for Prempro. If you want to know more about Prempro, talk with your doctor or pharmacist.

Prempro is a brand-name medication that comes as a tablet that you swallow. It isn’t available in a generic version. This article describes dosages of Prempro oral tablet.

Boxed warnings

This drug has boxed warnings about the risk of dementia and breast cancer. It also has a boxed warning about the risk of serious heart and blood vessel problems. A boxed warning is the most serious warning from the Food and Drug Administration (FDA).

For details, see the “Dosage of Prempro” section below. See the end of this article for more information about these warnings.

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Form and strengths of Prempro

Prempro comes as a tablet that you swallow. It is a combination of estrogen (conjugated estrogen) and progestin (medroxyprogesterone). Prempro comes in four different strengths in milligrams (mg) with varying amounts of estrogen and progestin.

• 0.3 mg conjugated estrogen with 1.5 mg medroxyprogesterone
• 0.45 mg conjugated estrogen with 1.5 mg medroxyprogesterone
• 0.625 mg conjugated estrogen with 2.5 mg medroxyprogesterone
• 0.625 mg conjugated estrogen with 5 mg medroxyprogesterone

Dosage of Prempro

This article describes the recommended dosages for Prempro oral tablet. The drugmaker provides these dosages.

If your doctor prescribes this medication, you should follow the dosage they prescribe. Your doctor will determine the dosage that best meets your needs. Do not change your dosage of Prempro oral tablet without your doctor’s recommendation.

Usual recommended dosages of Prempro in adults

Usually, doctors start by prescribing a low dosage of Prempro oral tablet. Then, they’ll adjust it over time until the right dosage is reached. Ultimately, your doctor will prescribe the smallest dosage of Prempro oral tablet that gives the desired outcome.

Prempro oral tablet can be used to treat certain symptoms due to menopause. These include hot flashes, night sweats, and certain vaginal symptoms, like dryness and irritation. It can also be used to prevent osteoporosis in postmenopausal women. Regardless of why you are prescribed Prempro oral tablet, you will still take 1 tablet daily.

• Dose: 1 tablet
• Frequency: daily

Your doctor will increase the strength you take based on how you respond to your current dose.

Dosage adjustments for Prempro

Your doctor will prescribe a dosage of Prempro oral tablet based on several factors. These include:

• the specific condition being treated and how severe it is
• your age
• other health conditions you may have

Missed dose of Prempro

Talk with your doctor or pharmacist right away if you realize you forgot to take a dose of Prempro oral tablet. They may advise you to take the missed dose. Or they may advise you to skip it and take your next dose as scheduled.

For tips on how to plan your doses of Prempro oral tablet and avoid missing a dose, read this article. You could also try:

• downloading a reminder app on your phone
• setting an alarm
• putting a note where you’ll see it, such as on your calendar, bathroom mirror, or bedside table

Frequently asked questions

Below are answers to some commonly asked questions about Prempro oral tablet and its dosage.

Should I take my dose of Prempro in the morning or at night?

You can take Prempro oral tablet in the morning or at night. But to best manage your symptoms, you should take it at the same time every day. So take it at a time that is easiest and most convenient for you.

If you have questions about when to take Prempro oral tablet for your specific condition, speak with your doctor or pharmacist.

Can I take Prempro every other day?

Prempro oral tablet is not approved to be taken every other day. For treatment, it should be taken every day around the same time. But if you’re looking to stop taking Prempro, your doctor may recommend taking it every other day for a short period of time. This is to help prevent uncomfortable symptoms that could happen with a sudden decrease in hormones.

Speak with your doctor if you have questions about your Prempro oral tablet dosage.

What are the highest and lowest recommended doses of Prempro?

You should only take 1 tablet of Prempro daily. So the lowest recommended dose is 0.3 mg conjugated estrogen with 1.5 mg medroxyprogesterone, which is the lowest available tablet strength. The highest recommended dose is 0.625 mg conjugated estrogen with 5 mg medroxyprogesterone, which is the highest available tablet strength.

Speak with your doctor to learn more about the dosage of Prempro oral tablet.

Is Prempro taken long term?

Yes, doctors typically prescribe Prempro oral tablet as a long-term treatment. If you and your doctor determine that it’s safe and effective for your condition, you’ll likely take it long term.

But your doctor will most likely evaluate you periodically to make sure you still need it. If you no longer need Prempro oral tablet, it should be stopped.

If you have questions about how long you should take Prempro oral tablet, talk with your doctor.

How Prempro is taken

You’ll swallow Prempro oral tablet once per day.

Your doctor may advise that you take this medication around the same time each day. This helps keep a consistent amount of the drug in your body. And that can help the drug work more effectively.

If it’s hard for you to swallow tablets, view this article. It provides suggestions on how to swallow medications that come in pill form.

Also, be sure to talk with your doctor or pharmacist if you’re having difficulty taking your medication. They can offer recommendations about taking it.

Prempro coupon

Visit this page to access Optum Perks coupons and get price estimates for Prempro oral tablet when you use the coupons. These coupons can provide significant savings on your prescription costs. 

Note: Optum Perks coupons cannot be used with insurance copays or benefits.

Download the free Optum Perks Discount Card to save up to 80% on some prescription medications.

Overdose of Prempro

It’s important that you do not take more Prempro oral tablet than your doctor prescribes. Doing so can lead to harmful effects.

Symptoms of Prempro overdose

Symptoms of an overdose can include:

• nausea
• vomiting
• breast tenderness
• abdominal pain
• drowsiness and fatigue
• withdrawal bleeding

What to do if you take too much Prempro

If you think you’ve taken too much Prempro, call your doctor or pharmacist right away. Or you could call 800-222-1222 to speak with someone at America’s Poison Centers. You can also use its online resource. If you have severe symptoms, call 911 or a local emergency number immediately. You can also go to the closest emergency room.

What to ask your doctor

This article describes the usual recommended dosages for Prempro oral tablet. If your doctor prescribes this medication, they’ll determine the dosage that’s best for you.

Do not change your dosage of Prempro oral tablet without your doctor’s recommendation. You should take Prempro oral tablet exactly as your doctor prescribes it. Let your doctor know if you have concerns or questions about your treatment plan.

Here’s a list of some possible questions you may want to ask your doctor:

• Will you be changing my dosage of Prempro if my current dose isn’t working for me?
• Will Prempro interact with any of my current prescribed medications?
• How will I know if my dosage of Prempro is working for me?

Boxed warnings for Prempro

Prempro oral tablet has boxed warnings about the risk of dementia and breast cancer. It also has a boxed warning about the risk of serious heart and blood vessel problems. A boxed warning is the most serious warning from the FDA.

Serious heart and blood vessel problems: Estrogen plus progestin therapy, like Prempro, should not be used to prevent cardiovascular disease. Some studies have shown an increased risk of blood clots. These clots could go to your limbs or lungs. They could also cause a stroke or heart attack. Seek medical attention if you have pain or swelling in your arm or leg, difficulty breathing, or weakness on one side of your body. Speak with your doctor to learn more about the signs and symptoms of these cardiovascular events.

Probable dementia: Estrogen plus progestin therapy, like Prempro, should not be used to prevent dementia. Some studies have shown an increased risk of developing probable dementia in postmenopausal women ages 65 years or older. The risk of developing probable dementia in women younger than ages 65 years is still unknown. Speak with your doctor if you have concerns about your memory or cognition.

Breast cancer: Estrogen plus progestin therapy, like Prempro, has shown to increase your risk of invasive breast cancer. Because of this, Prempro should be prescribed at the lowest effective dose and for the shortest duration possible. Speak with your doctor to learn more about your risk of breast cancer with Prempro and what you should monitor while taking it.

For details, see the “Dosage of Prempro” section above. You can also talk with your doctor to learn more.

Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.