This article describes Praluent injection’s dosages and strengths and gives details on how to take it. You’ll also find information on cost savings and coupon options for Praluent. If you want to know more about Praluent, see this overview article. It covers details about the drug’s uses, side effects, and more.
Praluent is a brand-name medication that comes as an injection given under the skin. This article describes dosages of Praluent.
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Form and strengths of Praluent
Praluent injection comes as follows:
- Form: single-dose, prefilled pen with a solution for injection under the skin
- Strengths: 75 milligrams per milliliter (mg/mL), 150 mg/mL
Dosage of Praluent
This article describes the recommended dosages for Praluent injection. The drugmaker provides these dosages.
If your doctor prescribes this medication, you should follow the dosage they prescribe. Your doctor will determine the dosage that best meets your needs. Do not change your dosage of Praluent injection without your doctor’s recommendation.
Usual recommended dosages of Praluent in adults
Your doctor will prescribe a dosage of Praluent injection based on the condition you’re taking Praluent for. Praluent injection can be used once every 2 weeks or once every 4 weeks.
The following table shows the recommended starting dosages of Praluent for adults in milligrams. Note that the starting dosage for all conditions aside from homozygous familial hypercholesterolemia can be increased to 150 mg every 2 weeks as maintenance dosage if cholesterol needs to be lowered further.
| Condition or purpose | Recommended starting dosage |
|---|---|
| reduce the risk of heart attack, stroke, or chest pain in adults with cardiovascular disease | 75 mg once every 2 weeks or 300 mg once every 4 weeks |
| primary hyperlipidemia (a type of high cholesterol) | 75 mg once every 2 weeks or 300 mg once every 4 weeks |
| heterozygous familial hypercholesterolemia (HeFH) | 75 mg once every 2 weeks or 300 mg once every 4 weeks |
| homozygous familial hypercholesterolemia (HoFH) or HeFH in people receiving cholesterol apheresis (a procedure to lower cholesterol by removing blood from the body) | 150 mg once every 2 weeks |
Dosage of Praluent in children
Praluent injection is used to lower low-density lipoprotein (LDL) cholesterol in children ages 8 years and older with heterozygous familial hypercholesterolemia (HeFH). It’s used along with a balanced diet and other cholesterol medications.
Your child’s doctor will prescribe a dosage of Praluent injection based on their body weight. The following table shows the recommended dosages of Praluent injection for children in milligrams.
| Body weight | Recommended dosage |
| less than 50 kilograms (kg) | Starting dosage: 150 mg once every 4 weeks Dosage can be increased to 75 mg every 2 weeks if cholesterol needs to be lowered further. |
| 50 kg or more | Starting dosage: 300 mg once every 4 weeks Dosage can be increased to 150 mg every 2 weeks if cholesterol needs to be lowered further. |
Dosage adjustments for Praluent
Your doctor will prescribe a dosage of Praluent injection based on several factors. These include:
- the specific condition being treated and how severe it is
- your age
- your body weight
Missed dose of Praluent
Talk with your doctor or pharmacist right away if you realize you forgot to take a dose of Praluent injection. They may advise you to take the missed dose. Or they may advise you to skip it and take your next dose as scheduled.
For tips on how to plan your doses of Praluent injection and avoid missing a dose, read this article. You could also try:
- downloading a reminder app on your phone
- setting an alarm
- putting a note where you’ll see it, such as on your calendar, bathroom mirror, or bedside table
Frequently asked questions
Below are answers to some commonly asked questions about Praluent injection and its dosage.
When is the best time of day to take my Praluent dose?
The drugmaker hasn’t specified the best time of day to take your Praluent dose. When to take Praluent injection is a personal decision, and the time of day it’s taken doesn’t make a difference.
If you have more questions about this, talk with your doctor.
Is Praluent used long term?
Yes, doctors typically prescribe Praluent injection as a long-term treatment. If you and your doctor determine that it’s safe and effective for your condition, you’ll likely use it long term.
If you have questions about how long you should use Praluent injection, talk with your doctor.
How Praluent is used
Your healthcare professional will train you on how to administer your Praluent injection.
You’ll inject Praluent once every 2 weeks or once every 4 weeks. It should be injected under the skin of your thighs, stomach, or upper arms. But avoid injecting it in any area within 2 inches of your belly button or any areas that are tender, bruised, hard, red, or discolored. Also avoid injecting into areas where you can see veins, scars, or stretch marks. Your doctor will likely recommend that you change injection sites, or inject your dosage in a different place than the last injection.
Your doctor may advise that you take this medication around the same time each day you take a dose. This helps keep a consistent amount of the drug in your body. And that can help the drug work more effectively.
Also, be sure to talk with your doctor or pharmacist if you’re having difficulty taking your medication. They can offer recommendations about taking it.
Praluent coupon
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