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Foods to avoid when taking Trulicity

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Foods to avoid Foods to try Trulicity and alternativesSummary
Trulicity is a medication that helps regulate blood sugar levels. While taking it, it’s best to avoid certain foods and drinks, such as white bread, alcohol, and fatty foods.
Medically reviewed by Alyssa Walton, PharmD
Written by Suan Pineda
Updated on

Trulicity is a brand-name prescription medication that helps manage blood sugar levels in people with type 2 diabetes. The generic version is called dulaglutide. A generic medication is a copy of the active ingredient in a brand-name drug.

Trulicity comes in liquid form that you’ll inject under the skin in your stomach, upper arm, or thigh. You’ll administer it once per week, ideally on the same day and at the same time. 

When you’re undergoing treatment with dulaglutide, you may consider avoiding specific things, including certain foods, that may cause negative interactions. These interactions can lead to uncomfortable symptoms like nausea and serious effects like kidney problems.

Foods to avoid 

A family cooking a vegetable dish together in a kitchen.
Photography by Counter/Getty Images

Medications like Trulicity are part of the treatment for type 2 diabetes. But your diet and lifestyle measures are equally important aspects of your treatment regimen.

When you have diabetes, you should consider limiting certain foods, such as very sugary or high fat foods. This can help prevent an increase in your blood sugar levels. And when you’re using Trulicity, you should pay special attention to certain foods so they don’t interact with the medication or worsen its side effects. 

Trulicity is a drug called a GLP-1 receptor agonist. It works by increasing the production of insulin, lowering the amount of sugar the liver releases, and slowing digestion. So, when you’re on Trulicity, you should try to avoid consuming foods and drinks that can interfere with these processes.

Some foods and drinks to avoid when you’re on Trulicity include:

Alcohol

Drinking alcohol can affect your blood sugar levels by lowering blood sugar, which can lead to hypoglycemia. This depends on how often and how much you drink. 

In general, the American Diabetes Association (ADA) recommends that people with diabetes limit drinking alcohol because it can interfere with how your liver works. When you have a drink, your liver will choose to metabolize alcohol over maintaining your blood sugar levels, according to ADA. 

Because dulaglutide already lowers how much sugar the liver releases, drinking while on Trulicity can lead to a dysregulation of blood sugar levels and cause hypoglycemia (low blood sugar). 

Yet there is no evidence that Trulicity and alcohol have any interactions or adverse effects themselves. Consider being cautious and speaking with a doctor if you have any concerns.

Refined grains

Foods made from refined grains, such as white rice, corn grits, and white bread, can increase blood sugar levels. Refined grains are high in carbohydrates, which spike sugar levels, and are easy to digest.

Some research from 2017 links refined grains with the development of type 2 diabetes, and experts generally recommend you avoid them.

While there is no established risk of administering Trulicity while eating refined grains, it may be counterintuitive to take the medication alongside foods that will spike your blood sugar since it can reduce the effectiveness of the drug.

Fried and fatty foods

Trulicity can slow digestion. So, eating fried and fatty foods, which take a long time to digest, can lead to discomfort and side effects like nausea and vomiting. 

Like refined grains, fried and fatty foods spike your blood sugar. That’s why eating these foods can counteract the effectiveness of Trulicity and make your liver work harder.

Added sugar

Having type 2 diabetes doesn’t mean you can never eat sweets. However, you should limit your intake of sugary foods and foods with added sugars, like molasses and high fructose corn syrups. 

Eating foods with added sugars — such as cookies, packaged juices, and sodas — can not only spike your sugar levels, they can also counteract the effects of dulaglutide.

If you need help covering the cost of medications, the free Optum Perks Discount Card could help you save up to 80% on prescription drugs. Follow the links on drug names for savings on that medication, or search for a specific drug here.

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Foods to try 

Dulaglutide may cause some discomfort when you start the medication. Because it slows digestion and affects the quantity of sugar your liver releases, you may experience nausea and vomiting as side effects.

When you start treatment with Trulicity, you can try eating bland foods to ease into it and reduce the risk of experiencing stomach-related side effects.

As you continue with the medication, you can favor certain foods to help you manage your blood sugar levels and promote overall health. These foods include:

  • leafy green vegetables
  • whole grains
  • beans and legumes
  • lean proteins, like fish and chicken
  • eggs
  • citrus fruits
  • berries
  • nuts

Certain types of diets and eating plans can also help people with diabetes manage sugar levels. The Centers for Disease Control and Prevention (CDC) recommends following the plate method, which consists of filling half your plate with vegetables, one quarter with lean protein, and the other quarter with carbohydrates.

Another recommended diet for people with diabetes is the Mediterranean diet.

Research from 2020 found that the Mediterranean diet not only prevented people from developing type 2 diabetes, it also decreased levels of HbA1c, a measurement of your blood sugar levels. 

Trulicity and alternatives

As a GLP-1 receptor agonist, Trulicity acts as the hormone that regulates blood sugar levels. Trulicity increases insulin production, slows digestion, and decreases how much sugar the liver releases. 

In some people, this can lead to certain side effects, such as:

  • nausea
  • diarrhea
  • heartburn
  • decreased appetite
  • feeling tired

Some serious side effects include difficulty breathing, hives and a rash, fast heartbeat, and changes in vision. If you experience any of these, reach out to a healthcare professional right away. 

Your healthcare professional may determine that Trulicity isn’t the right medication for managing your blood sugar levels, and they may prescribe other medications. Some alternatives to Trulicity include:

If you need help covering the cost of medications, the free Optum Perks Discount Card could help you save up to 80% on prescription drugs. Follow the links on drug names for savings on that medication, or search for a specific drug here.

Summary

Trulicity is a medication prescribed to regulate blood sugar in people with type 2 diabetes. It may be one part of your treatment plan for the condition, which often also includes diet and lifestyle measures.

During treatment with Trulicity, it’s best to avoid certain foods and drinks, such as alcohol, refined grains, and added sugars. This is because these foods and drinks can spike blood sugar levels and impair the effect of the medication. 

Download the free Optum Perks Discount Card to save up to 80% on some prescription medications.

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