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Hydromorphone, Dilaudid

Hydromorphone ER, Hydromorphone Hydrochlorideer

Hydromorphone (hye droe MOR fone) is a generic medication prescribed for severe pain that isn’t managed by other treatments. It’s prescribed for adults. Hydromorphone belongs to a group of drugs called opioids.

  • Generic
  • Tablet Extended Release 24 HR
  • 32mg
  • 30 Tablets

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Introduction

Written by Ashley Wong, PharmD
Medically reviewed by Christina Bookwalter PharmD, MS MEd, BCPS, BCACP 
Updated on October 25, 2023

Hydromorphone (hye droe MOR fone) is a generic medication prescribed for severe pain that isn’t managed by other treatments. It’s prescribed for adults. Hydromorphone belongs to a group of drugs called opioids.

This article doesn’t provide coupons for all forms of hydromorphone. To find coupons for some forms of hydromorphone, see these articles:

Note: The Food and Drug Administration (FDA) has not approved hydromorphone rectal suppository. This is because the drug was available before the FDA began its drug approval process. If you have questions about this, talk with your doctor or pharmacist.

Boxed warnings

Hydromorphone has boxed warnings about certain risks. Boxed warnings are the most serious warnings from the Food and Drug Administration (FDA). These warnings are:

  • risk of medication errors with hydromorphone injection and oral solution
  • risk of addiction and misuse* with hydromorphone oral tablet, extended-release (ER) oral tablet,† injection, oral solution, and rectal suppository
  • risk of serious respiratory depression with hydromorphone oral tablet, ER oral tablet,† injection, oral solution, and rectal suppository
  • risk of accidental ingestion or exposure with hydromorphone oral tablet, ER oral tablet,† oral solution, and rectal suppository
  • risk of neonatal withdrawal syndrome with hydromorphone oral tablet, ER oral tablet,† injection, oral solution, and rectal suppository
  • risk of serious harm if certain other drugs are used along with hydromorphone oral tablet, ER oral tablet,† injection, oral solution, and rectal suppository

For details, see the “Interactions and warnings for hydromorphone” section.

* Addiction means a drug is used even if it’s causing harm. Misuse means a drug is taken in a way other than how it’s prescribed. You may hear doctors refer to addiction and misuse as substance use disorder.
“Extended release” means the drug is released into your body slowly over a long period of time.