Bystolic
Nebivolol
Nebivolol (ne BIV oh lole) is a generic medication prescribed for high blood pressure in adults. Nebivolol belongs to a group of drugs called beta-blockers.
Nebivolol (ne BIV oh lole) is a generic medication prescribed for high blood pressure in adults. Nebivolol belongs to a group of drugs called beta-blockers.
- Generic
- • Tablet
- • 5mg
- • 90 Tablets
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Introduction
Written by Patricia Weiser, PharmD
Medically reviewed by Rosanna Sutherby, PharmD on May 21, 2023
This article describes nebivolol’s use, side effects, and more. Below you’ll also find some coupon options to help save on the cost of nebivolol.
Side effects of nebivolol
Nebivolol may cause mild or serious side effects. More common mild side effects of nebivolol and its serious side effects are listed below. This article doesn’t include all possible side effects of the drug. Side effects can vary based on your age, overall health, and any other medications you take.
To learn more about nebivolol’s side effects, ask your doctor or pharmacist. You can also read the prescribing information* for nebivolol.
* To view nebivolol’s prescribing information, see the “Article resources” section below.
Mild side effects
More common mild side effects of nebivolol are listed below. This article doesn’t include all possible mild side effects of the drug. To learn more about nebivolol’s side effects, see the drug’s prescribing information.*
With many drugs, mild side effects may go away within a few days or a couple of weeks. If the side effects are bothersome, tell your doctor or pharmacist. They may be able to suggest ways to manage them.
Nebivolol oral tablet’s mild side effects include:
- headache
- fatigue (low energy)
- dizziness
- nausea
- mild allergic reaction†
* To view nebivolol’s prescribing information, see the “Article resources” section below.
† For details about this side effect, see the “Interactions and warnings for nebivolol” section below.
Serious side effects
Serious side effects of nebivolol are listed below. This article doesn’t include all possible serious side effects of the drug. To learn more about nebivolol’s side effects, see the drug’s prescribing information.*
With many drugs, serious side effects are possible but not common. If you have serious side effects from this drug, call your doctor right away. If you’re having severe symptoms or a medical emergency, call 911 or a local emergency number.
In general, nebivolol’s serious side effects include:
- chest pain
- slow heart rate
- shortness of breath
- severe allergic reaction†
* To view nebivolol’s prescribing information, see the “Article resources” section below.
† For details about this side effect, see the “Interactions and warnings for nebivolol” section below.
Common questions about nebivolol
Below you’ll find answers to a few commonly asked questions about nebivolol.
Am I able to convert my dose of nebivolol to metoprolol?
No, you cannot convert your dose of nebivolol to metoprolol. Both drugs are used to treat high blood pressure, but they have different dosages.
If you and your doctor decide to switch your blood pressure medication, they’ll recommend the dosage that’s right for you. This depends on several factors, such as your health history and any other medications you take. It may also depend on the severity of your condition.
Is nebivolol a beta-blocker?
Yes, nebivolol belongs to a drug class called beta-blockers. Specifically, nebivolol is a third-generation beta-blocker. This group of beta-blockers selectively targets heart cells and helps relax blood vessels. Other third-generation beta-blockers include carvedilol and labetalol.
Beta-blockers are a type of blood pressure medication. Besides lowering blood pressure, some beta-blockers have other uses, too. Examples include treating certain types of chest pain, heart failure, and helping to prevent migraine episodes.
If you have more questions about beta-blockers, talk with your doctor or pharmacist.
Can nebivolol be used for anxiety?
Possibly. Anxiety is an off-label use of nebivolol. With off-label use, a drug is prescribed for a purpose other than its approved ones. Nebivolol is approved by the Food and Drug Administration (FDA) to treat high blood pressure in adults.
For more information about treating anxiety with nebivolol, talk with your doctor.
What brand names are available for nebivolol?
The brand-name version of nebivolol is Bystolic. Nebivolol is a generic drug. Generic drugs usually cost less than brand-name drugs. Both nebivolol and Bystolic are available by prescription.
Talk with your doctor or pharmacist if you have questions about how these drugs compare.
Does nebivolol 10 mg cause more side effects than the drug’s other strengths?
It’s possible that the 10-milligram (mg) strength of nebivolol causes more side effects than lower strengths. In general, the risk or severity of a drug’s side effects increases with higher strengths compared to lower strengths. This is because higher strengths have more active drug. Nebivolol oral tablets come in four strengths: 2.5 mg, 5 mg, 10 mg, and 20 mg.
To help prevent or lower the risk or severity of side effects, doctors will usually prescribe a lower strength of nebivolol to start. They may adjust your dosage over time until they reach the amount that manages your blood pressure well.
For more information about your nebivolol dosage or the drug’s side effects, talk with your doctor. You can also refer to the “Side effects of nebivolol” section above.
How does nebivolol work? And how long does it take to start working?
Nebivolol works in two main ways to treat high blood pressure. The drug blocks specific receptors* in the body, which slows your heart rate. Nebivolol also causes blood vessels to relax. These effects of nebivolol decrease your blood pressure.
Nebivolol starts working within 2 weeks to lower your blood pressure. But it may take more or less time, depending on how your body responds to the drug. You and your doctor will monitor your blood pressure during nebivolol treatment. They’ll likely ask you to check your blood pressure at home. With regular monitoring, your doctor can see how well the drug is working for you.
If you have questions about how nebivolol works to treat your condition, talk with your doctor or pharmacist.
* Receptors are proteins on the outside of cells that bind to other proteins or chemicals.
Nebivolol coupon
You may be able to save money on your prescription for nebivolol by using our Perks discount coupons. They can be found at the end of this article.
If you have questions about how to pay for nebivolol, talk with your doctor or pharmacist.
Note: Optum Perks coupons cannot be used with insurance copays or benefits.
Uses of nebivolol
The Food and Drug Administration (FDA) approves prescription drugs such as nebivolol for certain conditions. Approved uses for nebivolol are described below.
Use for lowering blood pressure
Doctors may prescribe nebivolol oral tablet for treating high blood pressure. It’s used for this purpose in adults. It’s usually prescribed as a long-term treatment.
Blood pressure is a measure of the amount of force your blood puts on your blood vessel walls. Doctors usually consider blood pressure to be within a normal range if it’s less than 120 over 80 millimeters of mercury (mm Hg). This is written as 120/80 mm Hg. With high blood pressure, your blood pressure is consistently 130/80 mm Hg or higher.
High blood pressure doesn’t usually cause symptoms. But without treatment, it can lead to serious health problems. Examples include heart failure, heart attack, stroke, and chronic kidney disease.
Doctors may prescribe nebivolol alone or together with other blood pressure medications.
Dosage of nebivolol
The dosage of nebivolol your doctor prescribes may vary based on your condition and certain other factors. Talk with your doctor about the dosage you should take.
Taking nebivolol
Nebivolol oral tablet is swallowed with or without food.
Your doctor will talk with you about how to take nebivolol. They’ll explain how much to take and how often. Always follow your doctor’s recommendation.
Overdose of nebivolol
You should not take more nebivolol than your doctor prescribes. For some drugs, doing so may lead to serious side effects or overdose.
If you think you’ve taken too much nebivolol, call your doctor or pharmacist right away. Or you could call 800-222-1222 to speak with someone at America’s Poison Centers. You can also use its online resource. If you have concerning symptoms, call 911 or a local emergency number immediately. You can also go to the closest emergency room.
Interactions and warnings for nebivolol
Below, you’ll find information about nebivolol’s possible interactions and warnings.
Interactions of nebivolol
Certain things may affect how a drug works. These include getting vaccines, consuming alcohol or certain foods, or taking the drug with other medications. This effect is called a drug interaction.
Before you take nebivolol, ask your doctor to check for possible interactions. Be sure to tell them about any of the following you take or use:
- prescription medications
- over-the-counter medications
- vitamins, herbs, or supplements
To learn about drug-condition interactions, see the “Warnings for nebivolol” section below.
Warnings for nebivolol
Some people should not take nebivolol and others should take it cautiously.
Nebivolol could cause harm to people with certain health conditions. This effect is called a drug-condition interaction. Other factors can also affect whether nebivolol is a safe option for you.
Ask your doctor about specific warnings for nebivolol, and be sure to tell your doctor about your:
- current health, including any allergies to medications
- past health conditions or surgeries
Allergic reaction
Nebivolol can cause an allergic reaction in some people. Severe allergic reactions are rare but possible.
If you’ve had an allergic reaction to nebivolol or any of its ingredients, your doctor will likely not prescribe nebivolol. They can tell you about medications that are safer options for you.
A mild allergic reaction may cause the following symptoms:
A severe allergic reaction may cause the following symptoms:
- swelling under your skin, usually in your hands, feet, eyelids, or lips
- swelling of your mouth, throat, or tongue, which can cause breathing problems
If you have an allergic reaction to nebivolol, call your doctor right away. If you have severe symptoms, call 911 or a local emergency number.
Pregnancy or breastfeeding and nebivolol
Information about nebivolol and pregnancy and breastfeeding is described below.
Nebivolol and pregnancy
There are risks to taking nebivolol during pregnancy, especially during the third trimester. But there are also risks with having untreated high blood pressure while pregnant. (Keep in mind that nebivolol is used for treating high blood pressure.)
If you’re planning a pregnancy or can become pregnant, talk with your doctor about high blood pressure treatment options during pregnancy. Together, you can discuss the risks and benefits of your treatment options. Your doctor can help determine whether you should take nebivolol during pregnancy.
Nebivolol and breastfeeding
It’s not known whether nebivolol should be taken while breastfeeding. If you’re currently breastfeeding or planning to do so, talk with your doctor before taking this medication.
What to ask your doctor
This article describes nebivolol’s uses and dosage, ways to save on cost, and more. Let your doctor know if you have questions about nebivolol or would like more details about it.
Here’s a list of some possible questions you may want to ask your doctor:
- Should I continue taking my other medications with nebivolol?
- How often should I check my blood pressure at home while taking nebivolol?
- What are my options if I have concerns about the cost of nebivolol?
Article resources
- Bystolic (nebivolol) tablets, for oral use. (2019). https://www.rxabbvie.com/pdf/bystolic_pi.pdf
- Ferri C. (2021). The role of nebivolol in the management of hypertensive patients: From pharmacological profile to treatment guidelines. https://www.futuremedicine.com/doi/10.2217/fca-2021-0048
- Food and Drug Administration. (2023). Orange Book: Approved drug products with therapeutic equivalence evaluations. https://www.accessdata.fda.gov/scripts/cder/ob/index.cfm
- Nebivolol tablets, for oral use. (2023). https://nctr-crs.fda.gov/fdalabel/services/spl/set-ids/ef3b8ec9-0cec-40d4-824f-fc2b6cafd39a/spl-doc
- Rubenfire M. (2018). 2017 Guideline for high blood pressure in adults. https://www.acc.org/latest-in-cardiology/ten-points-to-remember/2017/11/09/11/41/2017-guideline-for-high-blood-pressure-in-adults
Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
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