Dexlansoprazole
Generic Dexilant
Dexlansoprazole (deks lan SOE pra zole) is a generic medication prescribed for certain conditions related to high levels of stomach acid. Dexlansoprazole belongs to a group of drugs called proton pump inhibitors (PPIs).
Dexlansoprazole (deks lan SOE pra zole) is a generic medication prescribed for certain conditions related to high levels of stomach acid. Dexlansoprazole belongs to a group of drugs called proton pump inhibitors (PPIs).
- Generic
- • Capsule Delayed Release
- • 60mg
- • 30 Capsules
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Intro
Introduction
Written by Alex Brewer, PharmD, MBA
Medically reviewed by Victor Nguyen, PharmD, MBA
Updated on July 24, 2023
Dexlansoprazole (deks lan SOE pra zole) is a generic medication prescribed for certain conditions related to high levels of stomach acid. Dexlansoprazole belongs to a group of drugs called proton pump inhibitors (PPIs).
The Food and Drug Administration (FDA) has approved dexlansoprazole for treating heartburn and some related conditions.
Side effects
Side effects of dexlansoprazole
Dexlansoprazole may cause mild or serious side effects. More common mild side effects of dexlansoprazole and its serious side effects are listed below. This article doesn’t include all possible side effects of the drug. Side effects can vary based on your age, overall health, and any other medications you take.
To learn more about dexlansoprazole’s side effects, ask your doctor or pharmacist. You can also refer to the prescribing information for dexlansoprazole listed in the “Article resources” section.
Mild side effects
More common mild side effects reported with dexlansoprazole are listed below.
This article doesn’t include all possible mild side effects of the drug. To learn more about dexlansoprazole’s side effects, refer to the prescribing information for dexlansoprazole listed in the “Article resources” section.
With many drugs, mild side effects may go away within a few days or a couple of weeks. If the side effects are bothersome, tell your doctor or pharmacist. They may be able to suggest ways to manage them.
Dexlansoprazole delayed-release oral capsule’s mild side effects include:
- diarrhea
- pain in your abdomen
- nausea
- vomiting
- mild allergic reaction*
* For details about this side effect, see the “Interactions and warnings for dexlansoprazole” section.
Serious side effects
Serious side effects of dexlansoprazole are listed below.
This article doesn’t include all possible serious side effects of the drug. To learn more about dexlansoprazole’s side effects, refer to the prescribing information for dexlansoprazole listed in the “Article resources” section.
With many drugs, serious side effects are possible but not common. If you have serious side effects from this drug, call your doctor right away. If you’re having severe symptoms or a medical emergency, call 911 or a local emergency number.
In general, dexlansoprazole’s serious side effects include:
- Clostridioides difficile (C. diff) infection and severe diarrhea
- intestinal polyps (small growths of tissue in the colon)
- bone fractures
- sudden tubulointerstitial nephritis (a kidney condition)
- low vitamin B12 levels
- lupus (an autoimmune condition)
- low blood magnesium level
- severe allergic reaction*
* For details about this side effect, see the “Interactions and warnings for dexlansoprazole” section.
FAQs
Common questions about dexlansoprazole
Below you’ll find answers to a few commonly asked questions about dexlansoprazole.
What brand names are available for dexlansoprazole?
Dexlansoprazole is available as the brand-name drug Dexilant.
A generic medication is an identical copy of the active drug in a brand-name medication. (An active drug is the ingredient that makes a medication work.) Generics usually cost less than brand-name drugs. And they’re thought to be as safe and effective as the brand-name versions.
Talk with your pharmacist or doctor if you’d like to learn more about using the brand-name drug Dexilant rather than the generic drug dexlansoprazole.
Is dexlansoprazole similar to omeprazole?
Yes, dexlansoprazole and omeprazole are similar. Both are proton pump inhibitor (PPI) drugs prescribed to treat certain conditions related to high levels of stomach acid.
Dexlansoprazole and omeprazole cause similar side effects. Examples include low blood levels of vitamin B12, low blood magnesium, and increased risk of bone fractures.
Talk with your doctor or pharmacist if you’d like to learn more about how dexlansoprazole and omeprazole compare.
How does dexlansoprazole work? And how long does it take to start working?
Dexlansoprazole is a type of PPI drug. It works by blocking stomach acid production. This lowers the amount of acid in your stomach. It also helps to keep stomach acid from entering your esophagus.
If you’d like to know more about how dexlansoprazole works, talk with your doctor or pharmacist.
Uses
Uses of dexlansoprazole
The Food and Drug Administration (FDA) approves prescription drugs such as dexlansoprazole for certain conditions. Approved uses for dexlansoprazole are described below.
Use for certain digestive conditions
Doctors may prescribe dexlansoprazole for treating certain digestive conditions related to high levels of stomach acid. Specifically, the FDA has approved dexlansoprazole to:
- treat and heal erosive esophagitis (inflammation in the esophagus with erosions) and relieve heartburn related to this condition
- treat heartburn and other symptoms caused by gastroesophageal reflux disease (GERD)
It’s used for these purposes in adults and children ages 12 years and older. It’s usually prescribed as a short-term treatment.
With high levels of stomach acid, the lining of your stomach, small intestine, and esophagus can become irritated. This irritation can lead to ulcers. Ulcers are painful sores in the lining of your esophagus, stomach, and intestines. High levels of stomach acid can also cause heartburn, upset stomach, bloating, and loss of appetite.
Interactions and warnings
Interactions and warnings for dexlansoprazole
Below, you’ll find information about dexlansoprazole’s possible interactions and warnings.
Interactions of dexlansoprazole
Certain things may affect how a drug works. These include getting vaccines, consuming alcohol or certain foods, or taking the drug with other medications. This effect is called a drug interaction.
Before you take dexlansoprazole, ask your doctor to check for possible interactions. Be sure to tell them about any of the following you take or use:
- prescription or over-the-counter drugs
- vitamins, herbs, or supplements
To learn about drug-condition interactions, see the “Warnings for dexlansoprazole” section below.
Warnings for dexlansoprazole
Some people should not take dexlansoprazole, and others should use it cautiously.
Dexlansoprazole could cause harm to people with certain health conditions. This effect is called a drug-condition interaction. Other factors can also affect whether dexlansoprazole is a safe option for you.
Ask your doctor about specific warnings for dexlansoprazole, and be sure to tell your doctor about your:
- current health, including any allergies to medications
- past health conditions or surgeries
Allergic reaction
Dexlansoprazole can cause an allergic reaction in some people. Severe allergic reactions are rare but possible.
If you’ve had an allergic reaction to dexlansoprazole or any of its ingredients, your doctor will likely not prescribe dexlansoprazole. They can tell you about medications that are safer options for you.
A mild allergic reaction may cause the following symptoms:
A severe allergic reaction may cause the following symptoms:
- severe skin reactions, which may blister or peel
- swelling under your skin, usually in your hands, feet, eyelids, or lips
- swelling of your mouth, throat, or tongue, which can cause breathing problems
If you have an allergic reaction to dexlansoprazole, call your doctor right away. If you have severe symptoms, call 911 or a local emergency number.
Overdose of dexlansoprazole
If you take dexlansoprazole by mouth, you should not take more dexlansoprazole than your doctor prescribes. For some drugs, doing so may lead to harmful effects or overdose.
If you think you’ve taken too much dexlansoprazole, call your doctor or pharmacist right away. Or you could call 800-222-1222 to speak with someone at America’s Poison Centers. You can also use its online resource. If you have concerning symptoms, call 911 or a local emergency number immediately. You can also go to the closest emergency room.
Pregnancy or breastfeeding and dexlansoprazole
Information about dexlansoprazole and pregnancy and breastfeeding is described below.
Dexlansoprazole and pregnancy
It’s not known whether dexlansoprazole should be taken during pregnancy. If you’re planning a pregnancy or can become pregnant, talk with your doctor before taking this medication.
Dexlansoprazole and breastfeeding
It’s not known whether dexlansoprazole should be taken while breastfeeding. If you’re breastfeeding or planning to do so, talk with your doctor before taking this medication.
Ask your doctor
What to ask your doctor
Let your doctor know if you have questions about dexlansoprazole or would like more details about it.
Here’s a list of some possible questions you may want to ask your doctor:
- How does dexlansoprazole compare with other treatments for my condition?
- Is dexlansoprazole similar to over-the-counter Nexium?
- Does my health history raise my risk of side effects with dexlansoprazole?
- How long does my condition require treatment with dexlansoprazole?
Resources
Resources
- Dexlansoprazole delayed-release capsules, for oral use. (2023). https://nctr-crs.fda.gov/fdalabel/services/spl/set-ids/4f44e84f-6219-4445-a67d-df37d18b014d/spl-doc
- Food and Drug Administration. (2023). Orange Book: Approved drug products with therapeutic equivalence evaluations. https://www.accessdata.fda.gov/scripts/cder/ob/index.cfm
Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
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