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Latanoprost eye drops side effects: A detailed guide

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More common side effectsMild side effectsSerious side effectsFAQsCouponSide effects in detailWarningsAsk your doctor
Latanoprost eye drops are prescribed for lowering pressure in the eye. It’s a prostaglandin analog drug that may cause mild or serious side effects, including blurred vision and changes in eyelashes.
Medically reviewed by Dana Kim, PharmD
Updated on June 9, 2023

Specifically, latanoprost eye drops are approved to lower pressure in the eye when it’s increased due to glaucoma or ocular hypertension.

This article describes possible side effects of latanoprost eye drops. You’ll also find information on cost savings and coupon options for latanoprost. You can explore this overview article to learn more about latanoprost eye drops, including the drug’s uses, dosage, and more.

Latanoprost eye drops are a generic version of the brand-name drugs Xalatan. Latanoprost only comes as eye drops. It’s not available in another form.

More common side effects of latanoprost

Latanoprost eye drops may cause mild or serious side effects. Below are some of the more common side effects of this medication.

Commonly reported side effects of latanoprost eye drops include:

  • blurred vision*
  • itching, burning, and stinging of the eye
  • darkening skin of the eyelid

* To learn more about this side effect, see the “Side effects of latanoprost in detail” section below.

Mild side effects of latanoprost

Latanoprost may cause certain mild side effects. Usually, mild side effects are temporary and can be easily managed. Tell your doctor or pharmacist if you have side effects that don’t go away or become bothersome.

Mild side effects of latanoprost eye drops that occurred in studies include:

Latanoprost eye drops may cause more mild side effects than those listed above. For details, see the drug’s prescribing information.

* To learn more about this side effect, see the “Side effects of latanoprost in detail” section below.

Serious side effects of latanoprost

Latanoprost may cause certain serious side effects. If you have any serious side effects from latanoprost eye drops, call your doctor right away. But if you think you’re having a medical emergency or your side effects feel life threatening, take immediate action. Call 911, or a local emergency number, or go to the nearest emergency room.

After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. Visit MedWatch’s website if you’d like to notify the FDA about a side effect you’ve had with latanoprost eye drops.

Serious side effects reported with latanoprost eye drops include:

* To learn more about this side effect, see the “Side effects of latanoprost in detail” section below.

Common questions about side effects of latanoprost

Here are answers to some common questions about side effects of latanoprost eye drops. If you have other questions, talk with your doctor or pharmacist.

Does latanoprost cause long-term side effects?

Yes, in some cases, latanoprost eye drops may cause long-term side effects. These can last for a while or be permanent after you’ve stopped using the drug.

Examples of long-term side effects include:

  • changes in eye color
  • darkening of the eyelid
  • changes in eyelashes*
  • macular edema*

Talk with your doctor to learn more about these side effects and how to best manage them. Ask your doctor for more information about how long these side effects of latanoprost eye drops may last.

* To learn more about this side effect, see the “Side effects of latanoprost in detail” section below.

Why should I use latanoprost at night? If I use it during the day, will I have certain side effects?

Doctors usually recommend using latanoprost eye drops at night because the drops can cause irritated eyes and blurred vision.* However, the risk of side effects is the same regardless of whether you use latanoprost eye drops at night or during the day.

If you would like to use latanoprost eye drops at a different time of the day, talk with your doctor.

* To learn more about this side effect, see the “Side effects of latanoprost in detail” section below.

Can latanoprost cause changes in blood pressure?

No, latanoprost will not cause changes in blood pressure. That said, it will affect your intraocular pressure (IOP). This is the pressure inside of your eye.

Certain conditions can raise IOP, too. These include glaucoma and ocular hypertension. If it’s not treated, increased pressure in the eye can cause lasting vision damage.

If you’d like to know more about this, talk with your doctor or pharmacist.

Coupon for latanoprost

Visit this page to access Optum Perks coupons and get price estimates for latanoprost when you use the coupons. These coupons can provide significant savings on your prescription costs.

Note: Optum Perks coupons cannot be used with insurance copays or benefits.

Side effects of latanoprost in detail

Below you’ll find details on some of the side effects of latanoprost eye drops.

Changes in eyelashes

Changes in eyelashes were reported with latanoprost eye drops after the drug was approved for use. They did not occur in the drug’s studies. This side effect is usually mild.

Changes in eyelashes may include:

  • increased length
  • increased thickness
  • changes in the color

Ways to manage

If you notice changes in your eyelashes with latanoprost eye drops, tell your doctor. They can evaluate your symptoms and help you determine whether you need to stop treatment. Eyelashes usually return to their usual state after stopping treatment with latanoprost eye drops.

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Blurred vision

In studies, blurred vision was common in people using latanoprost eye drops. This side effect is usually mild.

With blurred vision, you have changes in vision that may make things appear less clear, dim, or clouded. It can also affect your peripheral (side) vision.

Ways to manage

If you have symptoms of blurred vision, tell your doctor right away. They’ll likely recommend other eye drops to use in addition to latanoprost. This can help relieve blurred vision.

Macular edema

Macular edema did not occur in studies of latanoprost eye drops. But it has been reported since the drug was approved for use. This side effect may be serious.

Macular edema is a buildup of fluid in the eye’s macula (the center of the retina). This swelling can affect vision. The condition is usually painless, and symptoms may include:

  • having blurred or wavy vision
  • seeing colors that appear faded or dull
  • having difficulty reading

Certain factors can increase the risk of macular edema during treatment with latanoprost eye drops. These include certain health conditions such as diabetes and a history of macular edema.

Ways to manage

If you have symptoms of macular edema, tell your doctor right away. They’ll likely recommend treating the swelling in your eye.

Allergic reaction

For some people, latanoprost eye drops can cause an allergic reaction.

Symptoms can be mild or serious, and they may include:

  • itchiness
  • skin rash
  • swelling under the skin, usually affecting eyelids, lips, hands, or feet
  • swelling of the mouth, tongue, or throat, which can make it hard to breathe
  • flushing (temporary warmth, redness, or deepening of skin color)

Ways to manage

For mild allergic reaction symptoms, such as a mild rash, call your doctor right away. They may recommend treatments to help manage your symptoms. They’ll also let you know whether you should keep taking the medication.

For severe allergic reaction symptoms, such as swelling or trouble breathing, call 911 or your local emergency number right away. These symptoms require immediate medical care because they can become life threatening. If you’ve had a serious allergic reaction to latanoprost eye drops, your doctor may recommend a different medication instead.

Warnings for latanoprost

Below are some factors you may want to discuss with your doctor before using latanoprost eye drops.

Warnings

It may not be safe for you to use latanoprost eye drops if you have specific health conditions. These are sometimes called drug-condition interactions. Other things may also affect whether latanoprost eye drops is a safe treatment option for you.

Before using latanoprost eye drops, tell your doctor about your health and medications you take. Things to consider include:

Also, if you wear contact lenses, you should remove them from your eyes before using latanoprost eye drops. Then wait at least 15 minutes after using the eye drops before you put your contacts in your eyes.

Latanoprost and pregnancy

It’s not known whether latanoprost eye drops should be used during pregnancy. If you’re pregnant, planning a pregnancy, or can become pregnant, talk with your doctor before using this medication.

Latanoprost and breastfeeding

It’s not known whether latanoprost eye drops should be used while breastfeeding. If you’re currently breastfeeding or planning to do so, talk with your doctor before using this medication.

Latanoprost and alcohol

Latanoprost eye drops are not known to interact with alcohol.

If you drink alcohol, talk with your doctor about whether it’s safe to consume it during your treatment with latanoprost eye drops.

What to ask your doctor

This article describes common and serious side effects of latanoprost eye drops. If your doctor prescribes this medication, they can discuss possible side effects with you. Let your doctor know if you have concerns or questions about treatment with this medication.

Here’s a list of some possible questions you may want to ask your doctor:

  • If I have side effects, does that mean latanoprost is working for me?
  • Does my health history increase my risk of side effects from latanoprost eye drops?
  • If I have side effects from latanoprost eye drops, should I try a lower dosage?

Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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