This article describes possible interactions with fluticasone nasal spray. Interactions can cause a drug to have a different effect on the body than expected. Interactions can occur due to medications, alcohol, or certain health conditions.
Fluticasone comes as topical forms you apply to the skin and inhaler forms that you inhale. Interactions of fluticasone may vary depending on the form of fluticasone you’re prescribed.
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Other drugs and fluticasone
The drugs in the list below may interact with fluticasone nasal spray. This article doesn’t include all drugs that may interact with fluticasone.
Drug classes or drugs that may interact with fluticasone nasal spray include:
- certain antibiotics:
- certain antifungals:
- drug examples: ketoconazole and itraconazole (Sporanox, Tolsura)
- what might happen: can increase the risk of side effects of fluticasone
- certain antiretroviral drugs:
- drug examples: ritonavir (Norvir) and nelfinavir (Viracept)
- what might happen: can increase the risk of side effects of fluticasone
- small molecule inhibitors or “nib” drugs:
- drug examples: ceritinib (Zykadia) and idelalisib (Zydelig)
- what might happen: can increase the risk of side effects of fluticasone
- conivaptan (Vaprisol):
- what might happen: can increase the risk of side effects of fluticasone
- nefazodone:
- what might happen: can increase the risk of side effects of fluticasone
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When to avoid fluticasone
Certain health conditions or other factors could increase some risks with fluticasone nasal spray. Because of this, doctors may not prescribe fluticasone in these cases. These health conditions or other factors are called contraindications.
The only contraindication for fluticasone nasal spray listed in the drug’s prescribing information is a past allergic reaction to fluticasone. If you’ve ever had an allergic reaction to fluticasone nasal spray, using it again may cause a life threatening allergic reaction.
Before you start using fluticasone, tell your doctor about any history of allergies that you have. They can recommend whether you should use fluticasone.
Other interactions and fluticasone
Interactions can occur with supplements, foods, vaccines, and some lab tests. Below you can learn whether fluticasone nasal spray has these interactions.
The information below doesn’t include all other possible interactions with fluticasone.
Fluticasone and food
Fluticasone nasal spray isn’t known to interact with foods. But this doesn’t mean interactions with foods can’t happen or won’t be identified later.
Because of this, talk with your doctor or pharmacist about what foods you should avoid while using fluticasone nasal spray.
Fluticasone and supplements
Before using fluticasone nasal spray, tell your doctor and pharmacist about any herbs you take, as well as vitamins and supplements. Doing so may help you avoid interactions.
If you have questions about interactions that may affect you, talk with your doctor or pharmacist.
Fluticasone interactions with herbs
Fluticasone nasal spray isn’t known to interact with any herbs. But this doesn’t mean interactions with herbs can’t happen or won’t be identified later.
Because of this, ask your doctor or pharmacist before taking any herbs or herbal products while using fluticasone nasal spray.
Fluticasone interactions with vitamins
Fluticasone nasal spray isn’t known to interact with any vitamins. But this doesn’t mean interactions with vitamins can’t happen or won’t be identified later.
Because of this, ask your doctor or pharmacist before taking any vitamins while using fluticasone nasal spray.
Fluticasone and vaccines
Fluticasone nasal spray isn’t known to interact with any vaccines. But this doesn’t mean interactions with vaccines can’t happen or won’t be identified later.
Because of this, talk with your doctor or pharmacist before receiving any vaccines while using fluticasone nasal spray.
Fluticasone and lab tests
Fluticasone nasal spray isn’t known to interact with lab tests. But this doesn’t mean interactions with lab tests can’t happen or won’t be identified later.
Because of this, talk with your doctor or pharmacist before having any lab tests performed while using fluticasone nasal spray.
Fluticasone and cannabis or CBD
Fluticasone nasal spray isn’t known to interact with cannabis (commonly called marijuana) or cannabis products such as cannabidiol (CBD). But this doesn’t mean interactions can’t happen or won’t be identified later.
As with any drug or supplement, tell your doctor before taking cannabis with fluticasone.
Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees.
Alcohol and fluticasone
Fluticasone nasal spray is not known to interact with alcohol.
If you drink alcohol, talk with your doctor about whether it’s safe to consume it while using fluticasone nasal spray.
Health factors and fluticasone
Certain medical conditions or other health factors may increase the risk of interactions with fluticasone nasal spray. Keep in mind that interactions could lead to side effects or affect how well the drug works. Before using fluticasone, tell your doctor about your health history. They’ll determine whether fluticasone is right for you.
These health conditions or other factors might interact with fluticasone nasal spray:
Preventing fluticasone interactions
You may be able to help avoid certain interactions with fluticasone nasal spray. Before using this drug, you may want to discuss possible interactions with your doctor and pharmacist.
Things to consider include:
- Whether you drink alcohol or use cannabis.
- Other medications and herbs you take, as well as vitamins and supplements. Your doctor or pharmacist can help you fill out a medication list.
- What to do if you are prescribed a new drug while using fluticasone nasal spray.
Using fluticasone exactly as prescribed can also help prevent interactions.
What to ask your doctor
If you have questions about fluticasone and possible interactions, talk with your doctor.
Questions you may want to ask your doctor include:
- Do other drugs that could be used to treat my condition have similar interactions?
- Does my risk of interactions depend on my dosage of fluticasone nasal spray?
- Should I tell you if I start taking another medication or supplement during my fluticasone nasal spray treatment?
Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
