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Diclofenac oral tablets dosage: A detailed guide

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Forms and strengthsDosageFAQHow it's takenCouponOverdoseAsk your doctorBoxed warnings
Doctors prescribe diclofenac oral tablets for adults to treat pain from certain medical conditions. You take it by mouth up to four times per day, depending on the form that’s prescribed.
Medically reviewed by Purva Singla, PharmD
Updated on

This article describes diclofenac oral tablets dosages and strengths and gives details on how to take them. You’ll also find information on cost savings and coupon options for diclofenac. If you want to know more about diclofenac oral tablets, see this overview article. It covers details about the drug’s uses, side effects, and more.

Diclofenac oral tablet is a generic version of the brand-name drug Lofena. Diclofenac delayed-release oral tablet and diclofenac extended-release oral tablet* are generic medications. Theyre not available in brand-name versions.

Diclofenac also comes in an eye drop, oral solution, oral capsule, and topical forms for the skin. Those forms aren’t described in this article, but you can learn more about them from your doctor.

* “Delayed release” means the drug releases into your body after a certain amount of time has passed. “Extended release” means the drug is released into your body slowly over a long period of time.

Boxed warnings

This drug has boxed warnings about the risk of serious heart and blood vessel problems and serious digestive problems. A boxed warning is the most serious warning from the Food and Drug Administration (FDA).

See the end of this article for more information about these boxed warnings.

Forms and strengths of diclofenac

Diclofenac comes in these forms and strengths:

FormHow to takeStrengths
oral tablettake by swallowing• 25 milligrams (mg)
• 50 mg
delayed-release oral tablettake by swallowing• 25 mg
• 50 mg
• 75 mg
extended-release oral tablettake by swallowing• 100 mg

With the oral tablet form, diclofenac starts working as soon as you swallow the tablet. “Delayed release” means the drug releases into your body after a certain amount of time has passed. “Extended release” means the drug is released into your body slowly over a long period of time.

Dosage of diclofenac

This article describes the recommended dosages for diclofenac oral tablets. The drugmaker provides these dosages.

If your doctor prescribes this medication, you should follow the dosage they prescribe. Your doctor will determine the dosage that best meets your needs. Do not change your dosage of diclofenac oral tablets without your doctor’s recommendation.

Usual recommended dosages of diclofenac in adults

Doctors prescribe diclofenac oral tablets to treat pain from certain medical conditions in adults. The content below notes the approved conditions for each of the tablet forms.

Usually, doctors start by prescribing a low dosage of diclofenac oral tablets. Then, they’ll adjust it over time until the right dosage is reached. Ultimately, your doctor will prescribe the smallest dosage of diclofenac oral tablets that gives the desired outcome.

Dosages of diclofenac oral tablet

Diclofenac oral tablet is approved to treat pain from certain medical conditions. The table below lists these conditions and the recommended dosages for treating them in milligrams (mg).

PurposeRecommended dosage
treat mild to moderate pain50 mg, to be taken 3 times per day
treat menstrual cramps50 mg, to be taken 3 times per day
relieve symptoms of osteoarthritis50 mg, to be taken 2–3 times per day
relieve symptoms of rheumatoid arthritis50 mg, to be taken 3–4 times per day

Dosages of diclofenac delayed-release (DR) oral tablet

Diclofenac DR oral tablet is approved to treat pain from certain medical conditions. The table below lists these conditions and the recommended dosages for treating them in mg.

PurposeRecommended dosage
relieve symptoms of osteoarthritis• 50 mg, to be taken 2–3 times per day
• 75 mg, to be taken 2 times per day
relieve symptoms of rheumatoid arthritis• 50 mg, to be taken 3–4 times per day
• 75 mg, to be taken 2 times per day
relieve symptoms of ankylosing spondylitis• 25 mg, to be taken 4 times per day

Dosages of diclofenac extended-release (ER) oral tablet

Diclofenac ER oral tablet is approved to treat pain from certain medical conditions. The table below lists these conditions and the recommended dosages for treating them in mg.

PurposeRecommended dosage
relieve symptoms of osteoarthritis100 mg, to be taken once per day
relieve symptoms of rheumatoid arthritis100 mg, to be taken once per day

Dosage adjustments for diclofenac

Your doctor will prescribe a dosage of diclofenac oral tablets based on several factors. These include:

  • the specific condition being treated and how severe it is
  • your age
  • other medications you take

Missed dose of diclofenac

Talk with your doctor or pharmacist right away if you realize you forgot to take a dose of diclofenac oral tablet. They may advise you to take the missed dose. Or they may advise you to skip it and take your next dose as scheduled.

For tips on how to plan your doses of diclofenac oral tablet and avoid missing a dose, read this article. You could also try:

  • downloading a reminder app on your phone
  • setting an alarm
  • putting a note where you’ll see it, such as on your calendar, bathroom mirror, or bedside table

Frequently asked questions

Below are answers to some commonly asked questions about diclofenac oral tablets and their dosages.

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Do older adults require a lower dose of diclofenac?

Yes, older adults (ages 65 years and above) may need a lower dose of diclofenac. Older adults have a higher risk of serious digestive, heart, blood vessel, and kidney problems during diclofenac treatment. Due to this risk, doctors may prescribe diclofenac in this group only if the benefits outweigh the risks. In this case, they’ll typically prescribe a dose that‘s lower than the recommended dose.

If you have more questions concerning your age and your dose of diclofenac, talk with your doctor.

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Is diclofenac taken long term?

Yes, it might be. Doctors may prescribe diclofenac oral tablets as a short-term or long-term treatment. If you and your doctor determine that it’s safe and effective for your condition, you may take it long term.

If you have questions about how long you should take diclofenac oral tablets, talk with your doctor.

How diclofenac is taken

You’ll swallow diclofenac oral tablet by mouth up to four times per day, as your doctor prescribes. You can take it with or without food. But you may lower the risk of an upset stomach by taking it with food.

Your doctor may advise that you take this medication around the same time each day. Doing so helps keep a consistent amount of the drug in your body. And that can help the drug work more effectively.

Do not crush, split, or chew any form of diclofenac oral tablet. Doing so can interfere with the way the medication works. If it’s hard for you to swallow tablets, view this article. It provides suggestions on how to swallow medications that come in pill form.

Also, be sure to talk with your doctor or pharmacist if you’re having difficulty taking your medication. They can offer recommendations about taking it.

Diclofenac coupon

Visit these pages to access Optum Perks coupons and get price estimates for diclofenac when you use the coupons.

These coupons can provide significant savings on your prescription costs.

Note: Optum Perks coupons cannot be used with insurance copays or benefits.

Overdose of diclofenac

It’s important that you do not take more diclofenac oral tablets than your doctor prescribes. Doing so can lead to harmful effects.

Symptoms of diclofenac overdose

Symptoms of an overdose can include:

What to do if you take too much diclofenac

If you think you’ve taken too much diclofenac, call your doctor or pharmacist right away. Or you could call 800-222-1222 to speak with someone at America’s Poison Centers. You can also use its online resource. If you have severe symptoms, call 911 or a local emergency number immediately. You can also go to the closest emergency room.

What to ask your doctor

This article describes the usual recommended dosages for diclofenac oral tablet. If your doctor prescribes this medication, they’ll determine the dosage that’s best for you.

Do not change your dosage of diclofenac oral tablet without your doctor’s recommendation. You should take whatever form of diclofenac oral tablet your doctor prescribes exactly as directed. Let your doctor know if you have concerns or questions about your treatment plan.

Here’s a list of some questions you may want to ask your doctor:

  • Will a higher dosage of diclofenac oral tablet increase my risk of side effects?
  • Which form is best for my condition: Diclofenac oral tablet, diclofenac delayed-release oral tablet, or diclofenac extended-release oral tablet?
  • How often will my dosage of diclofenac oral tablet change?

Boxed warnings for diclofenac

This drug has boxed warnings about the risk of serious heart and blood vessel problems and serious digestive problems. A boxed warning is the most serious warning from the Food and Drug Administration (FDA).

Risk of serious heart and blood vessel problems. Diclofenac oral tablets can cause serious heart and blood vessel problems, such as a stroke or heart attack. If you’ve recently had coronary artery bypass graft (CABG) surgery, this risk is higher. These problems can occur early during treatment. And the longer you take diclofenac, the risk is higher.

Due to this risk, your doctor may decide to prescribe you a different pain reliever.

During diclofenac treatment, seek emergency medical help right away if you experience symptoms of heart or blood vessel problems. These can include:

  • chest pain
  • shortness of breath
  • dizziness
  • weakness on one side of your body
  • trouble speaking

Do not take diclofenac oral tablets if you’ve had heart bypass surgery recently.

Risk of serious digestive problems. Diclofenac oral tablets can cause life threatening digestive problems. These include ulcers (sores), bleeding, and tears in your intestines or stomach. These side effects can occur at any time during treatment and without any warning signs. The risk is higher in some people. This includes older adults (ages 65 years and above) and people with a history of stomach problems.

Due to this risk, your doctor may decide to prescribe you a different pain reliever.

During diclofenac treatment, get medical help right away if you have any digestive problems. These can include:

  • black or tar-like stools
  • blood in your vomit
  • vomit that looks like coffee grounds

Talk with your doctor to learn more about these boxed warnings.

Disclaimer: Optum Perks has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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